Pharmacology News and Research

Latest Pharmacology News and Research

Potential drug offers hope for therapy-resistant breast cancer patients

UT Southwestern Simmons Cancer Center researchers have shown that a first-in-class molecule can prevent breast cancer growth when traditional therapies stop working.

8 Aug 2017

Scientists stop formation of protein clumps linked to ALS and frontotemporal dementia

Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

8 Aug 2017

Researchers find clues to how chemotherapy drug fuels cancer spread from the breast to lungs

The very same treatment that thwarts breast cancer has a dark side – it can fuel the spread of the disease to the lungs.

8 Aug 2017

Proton pump inhibitor use not linked to increased risk of Alzheimer's disease

The use of proton pump inhibitors does not increase the risk of Alzheimer's disease, shows a recent study from the University of Eastern Finland.

7 Aug 2017

Compound derived from cannabis may alter blood levels of antiepileptic drugs

New research published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), suggests that an investigational neurological treatment derived from cannabis may alter the blood levels of commonly used antiepileptic drugs.

7 Aug 2017

UVA researchers identify connection between dopamine neurons and brain’s circadian center

Neurons in the brain that produce the pleasure-signaling neurotransmitter dopamine also directly control the brain's circadian center, or "body clock" - the area that regulates eating cycles, metabolism and waking/resting cycles - a key link that possibly affects the body's ability to adapt to jet lag and rotating shift work, a new University of Virginia study has demonstrated.

3 Aug 2017

Biologic substance APOSEC shows promise for healing dermal wounds

APOSEC is a substance obtained from white blood corpuscles and was developed by a research group led by thoracic surgeon Hendrik Jan Ankersmit, Head of the Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration at MedUni Vienna.

3 Aug 2017

New drug may limit disease progression, provide better symptom relief to Parkinson's patients

Researchers at Binghamton University have developed a new drug that may limit the progression of Parkinson's disease while providing better symptom relief to potentially hundreds of thousands of people with the disease.

31 Jul 2017

Newly discovered physical biomarkers could help pinpoint stage-specific prognosis of Alzheimer’s

Diagnosing Alzheimer's disease and determining a patient's prognosis is an inexact business, and that stands in the way of better personalized care and advances in treatment.

28 Jul 2017

Inappropriate medication use linked to increased hospitalization risk in elderly people

Potentially inappropriate medication use was linked with a 16% increased risk of hospitalization in a population-based study of elderly individuals.

27 Jul 2017

Stem cells in the brain found to regulate aging

Scientists at Albert Einstein College of Medicine have found that stem cells in the brain's hypothalamus govern how fast aging occurs in the body.

26 Jul 2017

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it.

26 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

Alzheimer’s drug may be promising treatment for traumatic brain injury

Traumatic brain injury (TBI) is a major cause of disability and death globally, but medications have generally failed to benefit patients. A new study found that memantine, a drug that is used to treat dementia associated with Alzheimer's disease, may be a promising therapy.

21 Jul 2017

Engineered macrophages invade and engulf tumor cells in mouse models

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones.

19 Jul 2017

Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Study finds inappropriate prescription of antiplatelet drugs in older patients

A study has found that antiplatelet drugs, such as aspirin, are often inappropriately prescribed in acutely hospitalized older people.

19 Jul 2017

New study finds link between certain antibiotics during pregnancy and risk for birth defects

A new study has found links between certain antibiotics during pregnancy and major congenital malformations in newborns.

19 Jul 2017

Pharmacology News and Research

Latest Pharmacology News and Research

Potential drug offers hope for therapy-resistant breast cancer patients

Scientists stop formation of protein clumps linked to ALS and frontotemporal dementia

Researchers find clues to how chemotherapy drug fuels cancer spread from the breast to lungs

Proton pump inhibitor use not linked to increased risk of Alzheimer's disease

Compound derived from cannabis may alter blood levels of antiepileptic drugs

UVA researchers identify connection between dopamine neurons and brain’s circadian center

Biologic substance APOSEC shows promise for healing dermal wounds

New drug may limit disease progression, provide better symptom relief to Parkinson's patients

Newly discovered physical biomarkers could help pinpoint stage-specific prognosis of Alzheimer’s

Inappropriate medication use linked to increased hospitalization risk in elderly people

Stem cells in the brain found to regulate aging

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

New compound takes positive step toward creating drug for melanoma

Alzheimer’s drug may be promising treatment for traumatic brain injury

Engineered macrophages invade and engulf tumor cells in mouse models

Two cell types partner to protect pancreatic tumors from immune attack

Scientists manage to permeate living cells with small antibodies

Study finds inappropriate prescription of antiplatelet drugs in older patients

New study finds link between certain antibiotics during pregnancy and risk for birth defects

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