Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

Researchers designed nanoparticles representing RBDs of the S protein of animal sarbecoviruses and SARS-CoV-2 to evaluate their potential as a pan-sarbecovirus vaccine candidate.

31 Mar 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Study models the airborne transmission of COVID-19 in a hospital outpatient examination room

A recent work assessed infection control strategies for SARS-CoV-2 in hospital consultation rooms.

31 Mar 2022

Association between polyunsaturated fatty acid levels and COVID-19 prognosis

Researchers conducted a systematic review to assess the impact of polyunsaturated fatty acid levels on COVID-19-related hospitalization and mortality.

31 Mar 2022

Prevalence of breastmilk feeding among people with SARS-CoV-2 infection during pregnancy

Researchers evaluated the association between breastmilk feeding and the time of maternal SARS-CoV-2 infection during pregnancy and the rooming-in status during the hospitalization for delivery.

31 Mar 2022

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

An exciting study recently published in the PNAS underscores the role of a well-established cytokine IL-13 in protecting our cells against SARS-CoV-2.

31 Mar 2022

Study sheds light on the conformational dynamics of SARS-CoV-1 and SARS-CoV-2 spike proteins

New computational simulations of the behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins prior to fusion with human cell receptors show that SARS-CoV-2, the virus that causes COVID-19, is more stable and slower changing than the earlier version that caused the SARS epidemic in 2003.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Inconsistency in disease severity across SARS-CoV-2 variants

Researchers determine how the severity of successively dominant SARS-CoV-2 variants has changed since the beginning of the pandemic.

30 Mar 2022

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Researchers demonstrated the inhalation of an ACE2 decoy receptor, sACE22.v2.4-IgG1, increases survival and ameliorates lung injury in K18-hACE2 transgenic mice.

30 Mar 2022

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers proposed an optimal system to generate SARS-CoV-2 virus-like particles for examining viral assembly and entry into target host cells.

30 Mar 2022

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

30 Mar 2022

Study examines pediatric emergency department attendance trends during the first COVID-19 wave in Europe

Researchers investigated the impact of SARS-CoV-2 infection and the adoption of preventive measures in pediatric emergency department attendances in Europe.

30 Mar 2022

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Study models the airborne transmission of COVID-19 in a hospital outpatient examination room

Association between polyunsaturated fatty acid levels and COVID-19 prognosis

Prevalence of breastmilk feeding among people with SARS-CoV-2 infection during pregnancy

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

Study sheds light on the conformational dynamics of SARS-CoV-1 and SARS-CoV-2 spike proteins

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Inconsistency in disease severity across SARS-CoV-2 variants

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

SARS-CoV-2 and pandemic chilblains

A summary of SARS-CoV-2 RNA-protein interactome studies

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Study examines pediatric emergency department attendance trends during the first COVID-19 wave in Europe

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

Antiviral functions of interferon regulatory factors during human coronavirus infection

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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