T Cell News and Research

Latest T Cell News and Research

Study shows how new antibiotic resistance genes arise from random DNA sequences

An important and still unanswered question is how new genes that cause antibiotic resistance arise. In a new study, Swedish and American researchers have shown how new genes that produce resistance can arise from completely random DNA sequences. The results have been published in the journal PLOS Genetics.

8 Jan 2021

Researchers investigate prognostic role of diversity of chromatin compartments in gynecological cancers

A novel marker might contribute to selecting high-risk stage I ovarian carcinoma patients for adjuvant chemotherapy and low-risk endometrial carcinoma patients for less extensive surgery.

8 Jan 2021

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Bruker Corporation and Evosep today announced major progress in high-sensitivity, quantitative true single-cell proteomics, using a modified timsTOF Pro mass spectrometer connected to an Evosep One low-flow chromatography system.

From Bruker Life Sciences Mass Spectrometry 8 Jan 2021

Researchers demonstrate lab tool that simplifies simulations of the human intestine

Rice University and Baylor College of Medicine researchers have found a way to mimic conditions in intestines, giving them a mechanical model for the real-time growth of bacterial infections.

8 Jan 2021

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Now, an intriguing recent study appeared on the bioRxiv * preprint server describes the use of in vitro evolution to elicit affinity maturation of the viral receptor-binding domain (RBD) of the spike protein to bind the host cell angiotensin-converting enzyme 2 (ACE2) with greater affinity.

7 Jan 2021

Glycylation essential to keep sperm swimming in a straight line, shows study

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells.

7 Jan 2021

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer.

7 Jan 2021

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center published promising findings today in the New England Journal of Medicine on preventing a common complication to lifesaving blood stem cell transplantation in leukemia.

7 Jan 2021

Chemicals in e-cigarettes disrupt the gut barrier and trigger inflammation

Touted by makers as a "healthy" alternative to traditional nicotine cigarettes, new research indicates the chemicals found in e-cigarettes disrupt the gut barrier and trigger inflammation in the body, potentially leading to a variety of health concerns.

7 Jan 2021

Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Cancer cells hibernate to survive harsh environment created by chemotherapy

Tapping into an ancient evolutionary survival mechanism, cancer cells enter into a sluggish, slow-dividing state to survive the harsh environment created by chemotherapy or other targeted agents.

7 Jan 2021

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

A recent study, currently available on the medRxiv* preprint server, is among the first to reveal the presence of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in colostrum and to demonstrate elevated cytokine levels in colostrum from women exposed to the virus.

7 Jan 2021

Potential treatment approach to new COVID-19 variant

Researchers in the United States have demonstrated a potential new approach to treating infection with the new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

7 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Researchers at the University of Gothenburg now suggest a possible cure for children with hard-to-treat forms of neuroblastoma using a new combination of drugs.

7 Jan 2021

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

A team of scientists from the University of Valencia and INCLIVA Health Research Institute, Spain, has recently investigated the durability of immune responses specifically developed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

7 Jan 2021

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

The University of Texas MD Anderson Cancer Center and Xencor, Inc. today announced a strategic research collaboration and commercialization agreement to develop novel CD3 bispecific antibody therapeutics for the potential treatment of patients with cancer.

7 Jan 2021

Repurposed drug can treat hearing loss in humans

According to the World Health Organization, around 466 million people worldwide have disabling hearing loss, a number the organization projects will double by 2050 to affect 1 in 10 people.

7 Jan 2021

Study reveals molecular machinery that regulates membrane association of Arf proteins

The small GTPases of the ADP-ribosylation factor (Arf) family are key initiators of various physiological processes including secretion, endocytosis, phagocytosis, and signal transduction. Arf family proteins function to mediate the recruitment of cytosolic effectors to specific subcellular compartments.

7 Jan 2021

T Cell News and Research

Latest T Cell News and Research

Study shows how new antibiotic resistance genes arise from random DNA sequences

Researchers investigate prognostic role of diversity of chromatin compartments in gynecological cancers

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Researchers demonstrate lab tool that simplifies simulations of the human intestine

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Glycylation essential to keep sperm swimming in a straight line, shows study

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Chemicals in e-cigarettes disrupt the gut barrier and trigger inflammation

Potential role of chitinase 3-like-1 in severity of COVID-19

Cancer cells hibernate to survive harsh environment created by chemotherapy

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

Potential treatment approach to new COVID-19 variant

Researchers provide comprehensive molecular characterization of head and neck cancers

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

Repurposed drug can treat hearing loss in humans

Study reveals molecular machinery that regulates membrane association of Arf proteins

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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