T Cell News and Research

Latest T Cell News and Research

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

Study uncovers why cancer patients with liver metastases have poor outcomes

Michael Green, M.D., Ph.D., noticed that when his patients had cancer that spread to the liver, they fared poorly – more so than when cancer spread to other parts of the body. Not only that, but transformative immunotherapy treatments had little impact for these patients.

4 Jan 2021

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues.

4 Jan 2021

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

One of the most promising areas of human cancer research is the study of signal transduction, or cell signaling.

4 Jan 2021

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Preliminary data from the non-powered U.S. Phase 2 study of 40 hospitalized patients shows that orally-administered opaganib was safe, with no material safety differences between opaganib and control arms.

4 Jan 2021

New cell therapy can boost immunotherapy against breast cancer

Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can be done by adding a small molecule to a treatment procedure called chimeric antigen receptor-T (CAR-T) cell therapy, according to a study by researchers at the UNC Lineberger Comprehensive Cancer Center.

4 Jan 2021

Scientists design experimental gut-brain system in a lab dish

Research into what is known as the gut-brain axis continues to reveal how the brain and gut influence each other's health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.

4 Jan 2021

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity.

4 Jan 2021

Researchers discover novel therapeutic strategy for ischemic stroke using experimental model

Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that a combination of an LSU Health-patented drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug. The findings are published in Brain Circulation, available here.

4 Jan 2021

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

29 Dec 2020

Protein employs twist‐and‐squeeze mechanism to expel chemotherapeutics from cancer cells

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences, discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years.

29 Dec 2020

Sustained immune dysregulation due to COVID-19 in non-hospitalized patients

COVID-19, which has killed 1.7 million people worldwide, does not follow a uniform path.

29 Dec 2020

UOC researchers to study the effects of intermittent fasting on aging in postmenopausal women

Although many treatments are offered for slowing down the impact of aging on health and physical appearance, there are no serious studies that prove their effectiveness on the biological effects of aging.

29 Dec 2020

Large transporter protein dysfunction associated with schizophrenia

Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.

29 Dec 2020

Gut cells alert the body to danger during parasite invasion

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder.

28 Dec 2020

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

The Phase 3 trial of another investigational coronavirus disease 2019 (COVID-19) vaccine has begun enrolling adult volunteers.

28 Dec 2020

Researchers develop new drug discovery method targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

28 Dec 2020

Self-learning algorithms can help analyze biological image data

Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience.

28 Dec 2020

Protein encourages similar developing cells to clump together

Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development.

24 Dec 2020

T Cell News and Research

Latest T Cell News and Research

Tissue healing after brain injury could spur tumor growth

Study uncovers why cancer patients with liver metastases have poor outcomes

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

P2 COVID-19 study shows no material safety differences between opaganib and control arms

New cell therapy can boost immunotherapy against breast cancer

Scientists design experimental gut-brain system in a lab dish

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

Researchers discover novel therapeutic strategy for ischemic stroke using experimental model

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Protein employs twist‐and‐squeeze mechanism to expel chemotherapeutics from cancer cells

Sustained immune dysregulation due to COVID-19 in non-hospitalized patients

UOC researchers to study the effects of intermittent fasting on aging in postmenopausal women

Large transporter protein dysfunction associated with schizophrenia

Gut cells alert the body to danger during parasite invasion

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

Researchers develop new drug discovery method targeting membrane proteins on live cells

Self-learning algorithms can help analyze biological image data

Protein encourages similar developing cells to clump together

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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