Testosterone

Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands

Testosterone Physiological Effects

Testosterone is the principle male sex hormone and is responsible for reproductive growth and development in male vertebrates.

Testosterone Biochemistry

Testosterone Treatments

What is Testosterone?

Testosterone Mechanism

Testosterone Replacement Therapy for Men: Risks and Benefits

Latest Testosterone News and Research

Paternal postpartum depression affects more fathers than widely recognized

Postpartum depression in mothers is a widely recognized condition that affects 1 in 7 women. But less known is that 1 in 10 new fathers also experience depression.

8 Jul 2026

Review highlights pregnancy and miscarriage rates among transmasculine people

A recent review of published research provides some evidence that a small but noteworthy minority of transmasculine people (trans, nonbinary, and other gender expansive people who were assigned female at birth) have pregnancies (6%–9%) and children (4%–9%), including after transition.

8 Jul 2026

Sleep apnea and erectile dysfunction share a stronger link than expected

A systematic review and meta-analysis of 8 observational studies found that greater obstructive sleep apnea severity was associated with poorer erectile function, with higher AHI linked to lower IIEF scores and higher minimum oxygen saturation linked to higher IIEF scores. The authors caution that the evidence remains observational, heterogeneous, and low certainty, so the findings support targeted screening rather than proving causality.

8 Jul 2026

Blood hormone signature could transform endometriosis diagnosis

People with endometriosis have a distinct pattern of hormones which could be identified by a blood test, with the potential to revolutionise diagnosis of the condition, research suggests.

6 Jul 2026

ReproNovo announces first participant dosed in EU Phase 2 trial of RPN-002 for embryo implantation

ReproNovo, a clinical-stage biopharmaceutical company committed to addressing critical gaps in male and female fertility as well as women’s health, today announced that the first participant has been dosed in the Company’s EU Phase 2 clinical trial of RPN-002, entitled Nolasiban Optimized Regimen Dosing for Inhibition of Uterine Contractility (NORDIC).

6 Jul 2026

Some statins may increase erectile dysfunction risk

Research indicates that certain statins, particularly atorvastatin and simvastatin, may elevate the risk of erectile dysfunction, impacting men's health.

6 Jul 2026

Imaging scans detect prostate cancer progression despite stable PSA levels

Patients with advanced prostate cancer may need periodic imaging scans to catch tumor growth even with stable levels of prostate-specific antigen (PSA), a protein in the blood that doctors routinely monitor for cancer progression, according to an analysis led by researchers at Weill Cornell Medicine and Duke University.

1 Jul 2026

Blood biomarker may predict Alzheimer's progression differently in men

A blood test does not lie, exactly. It reports a number. The question raised by a new mini-review in Brain Medicine, which gathers and weighs a decade of scattered findings, is whether clinicians have been reading the same number in two different ways without realizing it.

30 Jun 2026

Could your birth characteristics influence colorectal cancer risk?

A California study links birth and parental factors to early-onset colorectal cancer risk, highlighting male sex and Hispanic ethnicity as key contributors.

26 Jun 2026

PMOS rethink reframes a common hormone disorder as a whole-body disease

A new review reframes PCOS, now proposed as PMOS, as a systemic endocrine and metabolic disorder shaped by genetic, epigenetic, ovarian, metabolic, and neuroendocrine pathways. It highlights why inconsistent diagnosis and symptom-focused care have limited progress, while targeted therapies, biomarkers, machine learning, and organ-on-chip models may support more personalized treatment.

18 Jun 2026

GLP-1s may improve testosterone levels and sperm quality in men with obesity

GLP‑1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2026

Common plasticizer may trigger lifelong anxiety-related behavioral changes

Male rats that were exposed to the widely used plasticizer di-(2-ethylhexyl) phthalate (DEHP) during early development exhibited increased anxiety behavior as adults, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Study finds gaps in guideline-based testosterone prescribing practices

Only a small number of men who were prescribed testosterone therapy received appropriate, guideline-concordant diagnostic testing, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill, by Sophia Sinha, M.D., clinical assistant professor at the University of Michigan in Ann Arbor, Mich.

14 Jun 2026

Testosterone benefits older men with T2D risk when combined with lifestyle changes

Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Researchers identify neural hub for accurate sensory predictions

In the split second after you hear a noise, your brain is already making a potentially life-or-death deduction: Did I do that, or did something else? Our nervous systems answer this question using something called corollary discharge, a copy of a motor command that tells sensory areas what to expect from our own actions.

12 Jun 2026

Injectable semaglutide may improve fertility outcomes in PMOS

Researchers at the University of Colorado Anschutz have published a proof-of-concept study in Fertility and Sterility demonstrating that injectable semaglutide may offer meaningful reproductive benefits for women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS).

9 Jun 2026

Advancing Human Muscle Models for Drug Development and Preclinical Testing

Transforming drug development, Myomaker Bio's lab-grown muscle platforms offer human-relevant models for effective preclinical testing and risk reduction.

From Myomaker Bio 2 Jun 2026

Research challenges long standing beliefs about cannabis and male hormones

The effects of cannabis on the hormonal system and male fertility remain controversial within the scientific community. A study conducted by the University of Geneva (UNIGE), in collaboration with the Swiss Center for Applied Human Toxicology (SCAHT), provides a new answer by showing that cannabis use does not reduce testosterone levels in young men and may even increase its testicular synthesis.

28 May 2026

Why blood pressure rises faster in women after midlife

This review examines how sex-specific blood pressure trajectories are shaped by genetics, hormones, metabolic risk factors, lifestyle exposures, environmental stressors, and medical treatments. It highlights that women generally have lower blood pressure earlier in life but may experience steeper increases with aging, especially around and after menopause, with exogenous stressors appearing to have a greater impact in women than in men.

27 May 2026

Study links ceramide levels to prostate cancer drug response differences

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

26 May 2026