Testosterone

Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands

Testosterone Physiological Effects

Testosterone is the principle male sex hormone and is responsible for reproductive growth and development in male vertebrates.

Testosterone Mechanism

Testosterone Treatments

Testosterone Replacement Therapy for Men: Risks and Benefits

What is Testosterone?

Testosterone Biochemistry

Latest Testosterone News and Research

New research positions the placenta at the center of human neurodevelopment and evolution

In a Genomic Press Interview published today in Brain Medicine, Dr. Alex Tsompanidis highlights an exciting new idea that positions the placenta at the center of human neurodevelopment and evolution, challenging conventional wisdom about the origins of autism and human cognition.

16 Sep 2025

Study highlights menopause-related vocal changes in women

A new University of South Florida study published in Menopause highlights a largely overlooked health issue: voice changes that many women experience during menopause, often triggered by falling levels of estrogen and progesterone.

10 Sep 2025

Adding progesterone to gender-affirming hormone therapy improves breast growth for transgender people

The addition of the hormone progesterone to gender-affirming hormone therapy leads to increased breast growth for transgender people following feminising hormone therapy.

5 Sep 2025

Clinical trial finds pork meals enhance recovery and mood in military cadets

A newly published clinical trial in Nutrients highlights pork's role in military nutrition, showing that meals containing lean pork support better recovery, mood and anabolic status in cadets performing intense tactical fitness exercises compared to plant-based meals.

4 Sep 2025

Androgen deprivation therapy lowers satisfaction after penile prosthesis surgery

Prostate cancer is the most common malignancy among men, with over 160,000 new cases diagnosed annually in the United States.

1 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Review maps Toxoplasma hotspots: Half in Eastern Europe infected by age 44

Researchers systematically reviewed and modeled Toxoplasma gondii seroprevalence across 25 European countries. The study found striking regional differences, with highest infection levels in eastern and western Europe and lowest in the UK and northern regions.

1 Sep 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Male and female bovine embryos show distinct development paths

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

29 Aug 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Ultra-processed foods harm reproductive and metabolic health

Over the past 50 years, rates of obesity and type-2 diabetes have soared, while sperm quality has plummeted. Driving these changes could be the increasing popularity of ultra-processed foods, which have been linked to a range of poor health outcomes.

28 Aug 2025

Molecular profiling identifies prostate cancer patients who benefit most from chemotherapy

Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

28 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

Study reveals how SARS-CoV-2 hijacks testicular lipid metabolism to replicate

The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate.

21 Aug 2025

Understanding sex-based differences in immune system function

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older.

7 Aug 2025

Creatine in your diet may benefit your digestive system

Findings suggest dietary creatine from meat may alleviate chronic constipation, with stronger effects observed in men and those without certain health issues.

4 Aug 2025

Study debunks "No Nut November" claims: Abstinence shows no health benefits or harms

A new study in The Journal of Sexual Medicine found that participating in “No Nut November”, a month-long abstinence challenge, had no measurable effect on sexual well-being. The only significant difference was that participants reported higher sexual flexibility, likely reflecting a pre-existing trait.

29 Jul 2025

Promising new male birth control pill could be taken every three days

YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.

28 Jul 2025

Shared brain circuit drives opposite mating behaviors in male and female mice

In animals with social structures, the drive to reproduce is a complex process; governed by the brain, it's influenced by both internal cues such as hormones and external factors such as interactions with potential mates.

16 Jul 2025

Weight loss drugs can boost testosterone in men with obesity or diabetes

Anti-obesity medications can significantly raise testosterone levels and improve health outcomes for men with obesity or type 2 diabetes, according to a new study being presented Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

14 Jul 2025