Testosterone

Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands

Testosterone Physiological Effects

Testosterone is the principle male sex hormone and is responsible for reproductive growth and development in male vertebrates.

Testosterone Biochemistry

Testosterone Replacement Therapy for Men: Risks and Benefits

Testosterone Mechanism

What is Testosterone?

Testosterone Treatments

Latest Testosterone News and Research

Machine learning detects early brain changes linked to Alzheimer's disease

Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy.

5 Mar 2026

Combination therapy may help overcome barrier in early-stage prostate cancer treatment

A multi-institutional study led by Mayo Clinic and published in Cell Reports Medicine reports that pairing a next-generation immunotherapy with standard hormone therapy before surgery may help overcome a long-standing barrier in early-stage prostate cancer treatment.

26 Feb 2026

Social media muscle content raises steroid use intentions in young men

A study links muscle-focused social media content to increased intentions to use anabolic steroids among young men, highlighting risks of body comparison.

25 Feb 2026

Hormone-driven immune cells may explain sex differences in chronic pain

Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called monocytes, may help explain why.

22 Feb 2026

Sustained high progesterone during pregnancy can improve menstrual cyclicity in PCOS patients

Polycystic ovary syndrome (PCOS) affects 6%−20% of reproductive-aged women, and is commonly accompanied by irregular menstrual cycles and anovulatory infertility.

11 Feb 2026

Barriers to testosterone therapy drive men toward underground sources

Some men are resorting to obtaining testosterone replacement therapy (TRT) from underground sources due to significant barriers to accessing the therapy through formal medical channels, according to new Griffith University research.

9 Feb 2026

Public health workers are quitting over assignments to Guantánamo

Rebekah Stewart, a nurse at the U.S. Public Health Service, got a call last April that brought her to tears. She had been selected for deployment to the Trump administration's new immigration detention operation at Guantánamo Bay, Cuba.

9 Feb 2026

New meta-analysis challenges claims of athletic advantage for transgender women

A meta-analysis of 52 studies reveals insights into body composition and fitness in transgender athletes, challenging assumptions about competitive advantage.

6 Feb 2026

Why “low testosterone” has become a profitable masculinity crisis online

Social media's portrayal of low testosterone transforms masculinity into a marketable issue, linking health interventions to male identity and performance.

6 Feb 2026

Which hair loss supplements actually work?

Researchers compare the effectiveness and safety of multiple dietary supplements for hair loss.

4 Feb 2026

MRI scans reveal human brain growth from pregnancy through birth

Analyzing brain growth across pregnancy and early life, this study offers new insights into sex-specific development and its implications for neurodevelopment.

3 Feb 2026

Oxybutynin shows promise in managing hot flashes for prostate cancer patients

A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer.

2 Feb 2026

Study explores link between sex hormones and heart disease risk in type 2 diabetes

People with type 2 diabetes face a higher risk of heart attacks, strokes and other cardiovascular problems, according to the National Institutes of Health.

27 Jan 2026

Midlife insulin levels influence timing and duration of menopausal vasomotor symptoms

A woman's insulin levels in midlife are linked to the timing and duration of menopausal hot flashes, night sweats and cold sweats, according to new research from the University of Victoria (UVic).

27 Jan 2026

Ashwagandha aids recovery without blunting training stress in athletes

Six weeks of Ashwagandha root extract supplementation in semi-professional team-sport athletes was associated with sex-specific effects during pre-season training. Females showed improved perceived recovery with stable cortisol, while males demonstrated gains in lower-body power with stable cortisone levels.

18 Jan 2026

Can ketogenic diets help PCOS? New analysis points to weight and insulin gains

A systematic review and meta-analysis of 15 studies found that ketogenic diets were associated with short-term reductions in body weight, waist circumference, insulin resistance, and some reproductive hormones in women with polycystic ovary syndrome, primarily among those with overweight or obesity. However, substantial heterogeneity, low certainty of evidence, limited safety reporting, and short follow-up periods mean the clinical effectiveness and long-term sustainability of ketogenic diets in PCOS remain uncertain.

5 Jan 2026

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Scientists create light-controlled versions of cholesterol

High levels of cholesterol are linked to heart disease, stroke, and many other health problems. However, this complex and vital fatty, water insoluble molecule-a lipid-is found in every cell of the body and is not all bad news. It also regulates crucial processes that science has yet to map.

15 Dec 2025

Indiana University physician joins FDA panel on male hormone therapy

Helen Bernie, DO, MPH, assistant professor of urology at Indiana University School of Medicine, will participate in an expert panel on testosterone replacement therapy and men's health to be held Wednesday, Dec. 10, by the U.S. Food and Drug Administration. Bernie's role on the panel is that of a clinical expert on men's reproductive health, which is the focus of both her practice and academic research.

12 Dec 2025

Shorter hormone therapy may be enough for many men with prostate cancer

A study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that most of the benefits of androgen deprivation therapy (ADT) for prostate cancer occur within the first 9 to 12 months.

25 Nov 2025