Toxicology News and Research

Latest Toxicology News and Research

Plastics now commonly found in human stools

Nearly eight billion metric tons of plastic finds its way into the oceans each year. This huge amount of plastic either washes ashore or breaks down into tiny pieces that are less than 5 millimeters in diameter and are called microplastics.

22 Oct 2018

Environment impact of microplastics remains unclear

Scientists say there is not yet enough evidence to conclude that microplastics do or do not cause harm to the environment, following a review of more than 300 global studies.

17 Oct 2018

Researchers develop two-pronged approach for targeting Ebola virus

In a new study researchers have developed a two-pronged approach for targeting Ebola virus infection using linked nucleic acid (LNA) antisense oligonucleotides (ASOs)designed to interfere both genes essential for translation of Ebola virus genes and to block production of an intracellular human protein needed for the virus to enter cells.

12 Oct 2018

Study shows how fingerprint-based drug screening works on the living and deceased

New research published in the Journal of Analytical Toxicology shows how fingerprint-based drug screening can not only screen for the presence, or absence, of four classes of drugs of abuse, but that the technology also works when used by UK coroners to detect drugs in the sweat of fingerprint samples gathered from deceased individuals.

9 Oct 2018

New EU project aims to learn more about hormone-disrupting chemicals

Hormone-disrupting chemicals in our environment can affect early neurodevelopment in children, but little is known about the exact mechanisms for this interference. A new EU funded research project, coordinated from Karolinska Institutet, now aims to learn more and to develop better screening and testing tools.

26 Sep 2018

FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

Myelo Therapeutics GmbH announced today that the US Food and Drug Administration has granted an Orphan Drug Designation to its orally applied new chemical entity Myelo001 for the treatment of Acute Radiation Syndrome.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

New research suggests link between PFAS chemicals and hyperthyroidism in pet cats

New research suggests that there may be a link between higher levels of per- and polyfluoroalkyl substances in the environment and higher levels of hyperthyroidism in pet cats as they age. The findings are published in

20 Sep 2018

Purifying Proteins from Mammalian Cell Culture

In many cases mammalian cells are the only option to produce recombinant proteins with correct post-translational modifications, e.g. glycosylation, which are required for proper function of the therapeutic protein.

From Sartorius 18 Sep 2018

Researchers analyze how exposure to silver nanoparticles affects zebrafish

Silver nanoparticles are increasingly being used in consumer products, such as clothing and personal care products, in the medical and pharmaceutical industry, and in the food industry.

18 Sep 2018

LSTM led partnership receives funding to develop drug for treating two neglected tropical diseases

An LSTM led partnership has been awarded nearly £1.5 million from the Medical Research Council for the pre-clinical development of a candidate drug to treat onchocerciasis and lymphatic filariasis, by targeting the bacterial symbiont Wolbachia.

14 Sep 2018

Study reveals impact of Deepwater Horizon oil spill on oysters

Oysters likely suffered toxic effects from the oil dispersant Corexit® 9500 when it was used to clean up the 2010 Deepwater Horizon oil spill, said Morris Animal Foundation-funded researchers at the University of Connecticut.

14 Sep 2018

ADHD patients have increased risk of developing Parkinson's and other similar diseases

While about 11 percent of children (4-17 years old) nationwide have been diagnosed with attention-deficit hyperactivity disorder, the long-term health effects of having ADHD and of common ADHD medications remains understudied.

12 Sep 2018

BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

BioIVT, a leading provider of research models and services for drug development, today announced its research into the mechanisms involved in cholestatic drug-induced liver injury has been published in Applied In Vitro Toxicology.

10 Sep 2018

Low doses of common pesticide impact vertebrate neurodevelopment

New research published in Environmental Toxicology & Chemistry reveals that low doses of a commonly used pesticide potentially harm the Northern Leopard frog by inhibiting their brain development.

6 Sep 2018

New method may speed up development of novel drugs

Researchers of the University of Würzburg have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.

6 Sep 2018

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

A $2 million phase 2 Small Business Technology Transfer grant to optimize a promising new compound that has shown efficacy in preclinical studies against treatment-resistant multiple myeloma has been awarded to a Medical University of South Carolina startup company, Leukogene Therapeutics, Inc., in collaboration with MUSC researcher and company founder, Nathan G. Dolloff, Ph.D. Dolloff is an assistant professor in the Department of Cell and Molecular Pharmacology & Experimental Therapeutics at MUSC and a member of MUSC Hollings Cancer Center.

31 Aug 2018

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Hesperos, Inc., announced today the receipt of a NIH Phase I Small Business Innovation Research grant from the National Institutes of Health National Institute on Aging to help create a new multi-organ "human-on-a-chip" model that can realistically mimic the biology of Alzheimer's Disease and the effects of potential new therapies under realistic human physiological conditions.

29 Aug 2018

Widely-used artificial sweetener produces previously unidentified metabolites, study finds

Sucralose, a widely used artificial sweetener sold under the trade name Splenda®, is metabolized in the gut, producing at least two fat-soluble compounds, according to a recent study using rats.

27 Aug 2018

Illicit drug use is higher during celebratory events, may be worse than previously thought

America's drug problem may be even worse than officials realize. And illicit drugs are consumed at a higher rate during celebratory events. Those are just two of the conclusions scientists have drawn from recent studies of drug residues in sewage.

20 Aug 2018

Toxicology News and Research

Latest Toxicology News and Research

Plastics now commonly found in human stools

Environment impact of microplastics remains unclear

Researchers develop two-pronged approach for targeting Ebola virus

Study shows how fingerprint-based drug screening works on the living and deceased

New EU project aims to learn more about hormone-disrupting chemicals

FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

New research suggests link between PFAS chemicals and hyperthyroidism in pet cats

Purifying Proteins from Mammalian Cell Culture

Researchers analyze how exposure to silver nanoparticles affects zebrafish

LSTM led partnership receives funding to develop drug for treating two neglected tropical diseases

Study reveals impact of Deepwater Horizon oil spill on oysters

ADHD patients have increased risk of developing Parkinson's and other similar diseases

BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

Low doses of common pesticide impact vertebrate neurodevelopment

New method may speed up development of novel drugs

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Widely-used artificial sweetener produces previously unidentified metabolites, study finds

Illicit drug use is higher during celebratory events, may be worse than previously thought

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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