Consumer Medicine Information
PLEASE READ THIS INFORMATION CAREFULLY
What is in this leaflet
This leaflet answers some common questions about BRUFEN. It does not contain all the
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
BRUFEN against the benefits they expect it will have for you.
If you have any concerns about this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What BRUFEN is used for
BRUFEN relieves pain and reduces inflammation (swelling, redness or soreness) that
in different types of arthritis including rheumatoid arthritis, osteoarthritis and
juvenile rheumatoid arthritis
in muscle and bone injuries such as sprains, strains, lower back pain (lumbago), rheumatism,
and tendonitis, such as tennis elbow
from swelling and pain after setting broken or dislocated bones
menstrual cramps (period pain)
due to dental pain
BRUFEN also relieves fever (high temperature).
Although BRUFEN can relieve the symptoms of pain and inflammation, it will not cure
BRUFEN belongs to a group of medicines called non-steroidal anti-inflammatory drugs
Ask your doctor if you have any questions about why BRUFEN has been prescribed for
Your doctor may have prescribed BRUFEN for another reason.
This medicine is available only with a doctor's prescription.
BRUFEN is not addictive.
Before you take BRUFEN
When you must not take it
Do not take BRUFEN if you have an allergy to:
any product containing ibuprofen
any of the ingredients listed at the end of this leaflet
aspirin or any other NSAID medicine
Some of the symptoms of an allergic reaction may include:
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
hives, itching or skin rash
stomach ache, fever, chills, nausea and vomiting.
Many medicines used to treat headache, period pain and other aches and pains contain
aspirin or NSAID medicines. If you are not sure if you are taking any of these medicines,
ask your doctor or pharmacist.
If you are allergic to aspirin or any other NSAID medicines and take BRUFEN, these
symptoms may be severe.
Do not take BRUFEN if:
1. you are pregnant or intend to become pregnant.
BRUFEN may affect your developing baby if you take it during pregnancy.
2. you are breast-feeding or intend to breast-feed.
BRUFEN passes into breast milk and may affect your baby.
3. you have (or have previously) vomited blood or material that looks like coffee grounds.
4. you are (or have previously) bleeding from the rectum (back passage), have black sticky
bowel motions (stools) or bloody diarrhoea.
5. you have a condition resulting in an increased tendency to bleed.
6. you have a peptic ulcer (i.e. stomach or duodenal ulcer), a recent history of one,
or have had peptic ulcers before.
7. you have, or have a history of, Ulcerative Colitis or Crohn's Disease
8. you have severe heart failure
9. you have severe liver disease
10. you have severe kidney disease
Do not take this medicine/it after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if:
1. you have any allergies to:
any other substances, such as medicines, foods, preservatives or dyes
2. you are pregnant or intend to become pregnant.
Like most NSAID medicines, BRUFEN is not recommended to be used during pregnancy.
It may also impair female fertility.
3. you are breast-feeding or plan to breast-feed.
Like most NSAID medicines, BRUFEN is not recommended while you are breast-feeding.
4. you have or have had any medical conditions, especially the following:
heart disease or high blood pressure
heartburn, indigestion, stomach ulcer or any other stomach problems
vomiting blood or bleeding from the back passage
severe skin reactions such as Stevens-Johnson syndrome
liver or kidney disease
tendency to bleed or other blood problems
bowel or intestinal problems such as ulcerative colitis or Crohn's Disease
swelling of the ankles or feet
5. you currently have an infection
If you take BRUFEN while you have an infection, it may hide some of the signs and
symptoms of an infection. This may make you think, mistakenly, that you are better
or that it is not serious.
6. you plan to have surgery
If you have not told your doctor about any of the above, tell them before you start
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you buy without a prescription from your pharmacy, supermarket or health food
Some medicines and BRUFEN may interfere with each other. These include:
aspirin, salicylates or other NSAID medicines
warfarin, medicines used to stop blood clots
lithium, a medicine used to treat some types of depression
SSRIs such as sertraline, medicines used to treat depression
various medicines used to treat high blood pressure or other heart conditions
medicines used to treat heart failure such as digoxin
diuretics, also called fluid tablets
methotrexate, a medicine used to treat arthritis and some types of cancer
corticosteroids, such as prednisone, cortisone
ciclosporin or tacrolimus, medicines used to treat certain problems with the immune
system or to help prevent organ transplant rejection
aminoglycosides, medicines used to treat certain infections
Gingko biloba, an herbal medicine used to thin the blood
quinolone antibiotics, medicines used to treat certain infections
zidovudine, a medicine used to treat HIV
colestyramine, a medicine used to treat high cholesterol
sulfonylureas, medicines to treat diabetes
voriconazole or fluconazole, medicines to treat certain fungal infections
mifepristone (RU-486), a medicine used to end a pregnancy
These medicines may be affected by BRUFEN or may affect how well it works. You may
need to take different amounts of your medicine, or you may need to take different
Your doctor or pharmacist have more information on medicines to be careful with or
avoid while taking this medicine.
How to take BRUFEN
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist
How much to take
Your doctor will tell you how many BRUFEN tablets to take each day and when to take
Take the exact amount your doctor tells you to, no more or less.
Adults and Children Over 12 Years of Age
The usual daily dose of BRUFEN is one tablet taken three or four times a day.
In acute conditions, your doctor may prescribe two tablets three times a day.
Do not take more than six tablets in one day.
It is usual for elderly patients to be prescribed a smaller dose of BRUFEN.
The usual dose of BRUFEN is one to two tablets at the first sign of pain or menstrual
bleeding. Then take one tablet every 4 to 6 hours as necessary.
Do not take more than four tablets in one day.
How to take it
Take BRUFEN with or straight after food with a full glass of water.
This may help reduce the possibility of an upset stomach.
How long to take it
Do not take BRUFEN for longer than your doctor tells you to.
Depending on your condition, you may need BRUFEN for a few days, a few weeks or for
As with other NSAID medicines, if you are taking BRUFEN for arthritis, it will not
cure your condition, but it should help to control pain, swelling and stiffness.
BRUFEN usually begins to work within a few hours but several weeks may pass before
you feel the full effects of the medicine.
If you have arthritis, BRUFEN should be taken every day for as long as your doctor
For period pain, BRUFEN should be taken for a few days until the pain goes away.
If you are not sure how long to take BRUFEN for, talk to your doctor or pharmacist.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your tablets
as you would normally.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering when to take your medicine, ask your pharmacist for
If you take too much (overdose)
Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26)
or go to Accident and Emergency at your nearest hospital if you think that you or
anyone else may have taken too much BRUFEN. Do this even if there are no signs of
discomfort or poisoning.
You may need urgent medical attention.
If you take too much BRUFEN you may experience the following:
feel sick or vomit
have stomach pain
feel tired, drowsy or lack energy
feel dizzy or even become unconscious
have a headache or ringing in the ears
unusual eye movements, shivering, confusion, interrupted or breathing difficulties
low blood pressure, low or rapid heart beat
While you are using BRUFEN
Things you must do
If you are about to be started on any new medicine, remind your doctor and pharmacist
that you are taking BRUFEN.
Tell any other doctors, dentists and pharmacists that are treating you that you are
taking this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking
NSAID medicines can slow down blood clotting.
If you become pregnant while taking this medicine, tell your doctor immediately.
If you get an infection while taking this medicine, tell your doctor.
BRUFEN may hide some of the signs of an infection and may make you think mistakenly,
that you are better or that it is not serious. Signs of an infection may include fever,
pain, swelling and redness.
Tell your doctor if you get any visual disturbances such as blurred vision.
You may need to have an eye examination to make sure BRUFEN is not causing any side
Tell your doctor if, for any reason, you have not taken your medicine exactly as prescribed.
Otherwise your doctor may think that it was not effective and change your treatment
Tell your doctor if you feel the medicine is not helping your condition.
This will help your doctor to determine the best treatment for you.
Keep all of your doctor's appointments so that your progress can be checked.
Your doctor may want to take some blood tests from time to time. This helps to prevent
unwanted side effects.
Things you must not do
Do not take any other medicines to relieve pain and reduce inflammation while you
are taking BRUFEN without first telling your doctor.
aspirin (also called acetylsalicylic acid)
other medicines containing ibuprofen, the active ingredient in BRUFEN
any other NSAID medicine
Do not take BRUFEN to treat any other complaints unless your doctor tells you to.
Do not give BRUFEN to anyone else, even if they have the same condition as you.
Do not stop taking your medicine or lower the dosage without checking with your doctor.
Things to be careful of:
Be careful driving or operating machinery until you know how BRUFEN affects you.
As with other NSAID medicines, BRUFEN may cause dizziness or light-headedness, drowsiness
or blurred vision in some people.
If you have any of these symptoms, do not drive, operate machinery or do anything
else that could be dangerous.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking BRUFEN.
This medicine helps most people, but it may have unwanted side effects in a few people.
All medicines can have side effects. Sometimes they are serious, most of the time
they are not. You may need medical attention if you get some of the side effects.
If you are over 65 years of age, you may have an increased chance of getting side
Do not be alarmed by the following list of side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
nausea or vomiting
loss of appetite
heartburn or pain in the upper part of your stomach
cramps, wind, constipation or diarrhoea
buzzing or ringing in the ears or other trouble hearing
changes in mood, for example feeling anxious, depression, confusion, nervousness
These side effects are usually mild.
Tell your doctor immediately if you notice any of the following:
severe pain or tenderness in the stomach
eye problems such as blurred vision, sore red eyes, itching
signs of frequent or worrying infections such as fever, severe chills, sore throat
or mouth ulcers
bleeding or bruising more easily than normal, reddish or purplish blotches under the
signs of anaemia, such as tiredness, headaches, being short of breath, and looking
yellowing of the skin and/or eyes, also called jaundice
unusual weight gain, swelling of ankles or legs
tingling of the hands and feet
symptoms of sunburn (such as redness, itching, swelling, blistering) which may occur
more quickly than normal
severe or persistent headache
fast or irregular heartbeats, also called palpitations
These may be serious side effects of BRUFEN. You may need urgent medical attention.
Serious side effects are rare.
If any of the following happen, stop taking BRUFEN and tell your doctor immediately
or go to Accident and Emergency at your nearest hospital:
vomiting blood or material that looks like coffee grounds
bleeding from the back passage, black sticky bowel motions (stools) or bloody diarrhoea
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
asthma, wheezing, shortness of breath
sudden or severe itching, skin rash, hives
severe blisters and bleeding in the lips, eyes, mouth, nose and genitals (Stevens
fever, generally feeling unwell, nausea, stomach ache, headache and stiff neck
hearing difficulties, ringing in the ears
BRUFEN may be associated with a small increased risk of heart attack (myocardial infarction).
Blood disorders and kidney problems may occur with BRUFEN.
The above list includes very serious side effects. You may need urgent medical attention
or hospitalisation. These side effects are very rare.
Tell your doctor if you notice anything that is making your feel unwell.
Other side effects not listed above may occur in some patients.
After using BRUFEN
Keep your tablets in the pack until it is time to take them.
If you take the tablets out of the pack, they may not keep well.
Keep the tablets in a cool dry place where the temperature stays below 25°C.
Do not store BRUFEN or any other medicine in the bathroom or near a sink. Do not leave
it in the car or on window sills.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed,
ask your pharmacist what to do with any medicine that is left over.
What BRUFEN looks like
BRUFEN tablets are white, pillow shaped film-coated tablets.
The tablets are available in a blister pack containing 30 tablets.
BRUFEN contains 400 mg of ibuprofen as the active ingredient.
The inactive ingredients are:
colloidal anhydrous silica
sodium lauryl sulfate
BRUFEN does not contain gluten, tartrazine or any other azo dyes.
BRUFEN is supplied in Australia by:
Mylan Health Pty Ltd
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point, NSW 2000
For Medical Information Phone: 1800 314 527
AUST R 80659
Things that would be helpful for your arthritis
Some self-help measures suggested below may help your condition.
Talk to your doctor, physiotherapist, or pharmacist about these measures and for more
Your doctor may suggest losing some weight to reduce the stress on your joints.
May be recommended by your doctor or physiotherapist to help keep or improve movement
and strengthen muscles.
Ask a physiotherapist for an exercise plan suited to your condition.
As a general rule if any exercise hurts then do not do it.
Is important and is usually balanced with exercise and activity. Rest is needed when
joints are hot, swollen or painful.
Hot showers or baths may help to ease the pain and relax the muscles that can become
tense with arthritis. Your physiotherapist or doctor can prescribe other forms of
Are available to help with daily household tasks. For example, there are gadgets and
aids to help turn on taps, remove screw tops, pick up objects and handles that can
be fitted in bathrooms. Ask your doctor for more information.
This leaflet was prepared in February 2020.