Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Diflucan IV. It does not contain
all the available information. It does not take the place of talking to your doctor
All medicines have risks and benefits. Your doctor has weighed the risks of you being
given Diflucan IV against the benefits they expect it will have for you.
If you have any concerns about being given this medicine, ask your doctor or pharmacist.
Keep this leaflet.
You may need to read it again.
What Diflucan IV is used for
Diflucan IV is used to treat certain fungal and yeast infections.
It belongs to a group of medicines called azole antibiotics.
It works by preventing the growth of the fungal and yeast organisms causing your infection.
Ask your doctor if you have any questions about why Diflucan IV has been prescribed
Your doctor may have prescribed it for another reason.
Diflucan IV is available only with a doctor's prescription.
This medicine is not addictive.
When it must not be given
Diflucan IV should not be given if you have an allergy to:
any medicine containing fluconazole
medicines related to fluconazole such as miconazole, ketoconazole or clotrimazole
any of the ingredients listed at the end of this leaflet.
Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty
breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching
or hives on the skin.
If you are receiving doses of 400 mg or more a day of Diflucan IV, terfenadine (a
medicine used to treat allergies) should not be given.
Diflucan IV should not be given if you are taking cisapride (a medicine used to treat
Before you are given it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have any other health problems, including:
any liver problems
any heart problems
any kidney problems.
Tell your doctor if you are pregnant or if you plan to become pregnant or are breastfeeding.
Your doctor can discuss with you the risks and benefits involved.
If you have not told your doctor about any of the above, tell them before you are
given Diflucan IV.
Tell your doctor or pharmacist if you are taking any other medicines, including any
you get without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and Diflucan IV may interfere with each other. These include:
some medicines used to treat allergies
some medicines for diabetes such as glipizide, tolbutamide or glibenclamide
some antibiotics, antiviral and antifungal drugs such as rifampicin, rifabutin, zidovudine,
amphotericin B, erythromycin or voriconazole
some drugs used for heart problems, such as quinidine or verapamil
some drugs used in problems with the immune system, such as cyclosporin, tacrolimus,
sirolimus or tofacitinib
cyclophosphamide (used to treat certain types of cancers)
warfarin (used to stop blood clots)
phenytoin (used to treat epilepsy)
theophylline (used to treat asthma)
some benzodiazepines such as midazolam
hydrochlorothiazide (used for treating fluid problems)
the contraceptive pill (birth control pill)
carbamazepine (used in the treatment of epilepsy and bipolar disorder)
NSAIDS such as naproxen, diclofenac and celecoxib
Opioid pain killers such as alfentanil, fentanyl and methadone
losartan (used for treating high blood pressure)
antidepressants such as amitriptyline and nortriptyline.
These medicines and some others may be affected by Diflucan IV or may affect how well
it works. You may need different amounts of your medicines, or you may need to use
Talk to your doctor about the need for an additional method of contraception while
being given Diflucan IV.
Diflucan IV may decrease the effectiveness of some birth control pills.
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while taking Diflucan IV.
Receiving Diflucan IV
Diflucan IV can only be given by a doctor or nurse.
It is usually infused slowly into a vein.
The amount of Diflucan IV you receive, and the length of your treatment, will depend
on your body weight and kidney function. It will also depend on how quickly the infection
is brought under control.
After a while, the injection may be stopped and you may begin to receive Diflucan
capsules or oral suspension by mouth.
If you are given too much (overdose)
Because Diflucan IV is given to you by a health professional, overdose is unlikely
While you are receiving it
Things to be careful of
If you suffer from HIV or have a weakened immune system and develop a rash while being
given Diflucan IV, tell your doctor immediately.
If this rash worsens, Diflucan IV may need to be stopped.
Be careful when driving vehicles or operating machinery as it should be taken into
account that occasionally dizziness or seizures may occur.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are being given Diflucan IV.
This medicine helps most people with fungal and yeast infections, but it may have
a few unwanted effects in some people. All medicines can have side effects. Sometimes
they are serious, most of the time they are not. You may need medical attention if
you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Do not be alarmed by the following list of side effects. You may not experience any
Tell your doctor or pharmacist if you notice any of the following and they worry you:
nausea or feeling sick, vomiting
stomach pain, indigestion, diarrhoea
The above list includes the more common side effects of your medicine. They are usually
mild and short-lived.
Tell your doctor as soon as possible if you notice any of the following:
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
asthma, wheezing, shortness of breath
sudden or severe itching, skin rash, hives
fainting, seizures or fits
flaking of the skin
yellowing of the skin or eyes, also called jaundice
bleeding or bruising more easily than normal, reddish or purplish blotches under the
signs of frequent or worrying infections such as fever, severe chills, sore throat
or mouth ulcers
fast or irregular heart beat
These side effects are usually rare but can be serious and need urgent medical attention.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
This is not a complete list of all possible side effects. Others may also occur in
some people and there may be some side effects not yet known.
After using Diflucan IV
Diflucan IV should be kept in a dry place where the temperature stays below 30°C.
Your hospital pharmacy will store the Diflucan IV.
What it looks like
Diflucan IV is a clear, colourless solution and comes in clear glass vials of 50 mL
and 100 mL # .
# Not Available in New Zealand
Diflucan IV 50 mL and 100 mL vials contain fluconazole 2 mg/mL.
Sodium chloride 0.9% solution
Diflucan IV is supplied in Australia by:
Pfizer Australia Pty Ltd
Toll Free Number: 1800 675 229
Diflucan IV is supplied in New Zealand by:
Pfizer New Zealand Ltd
PO Box 3998
Toll Free Number: 0800 736 363
Australian Registration Numbers:
Diflucan IV (50 mL):
AUST R 47461
Diflucan IV (100 mL):
AUST R 47462
This leaflet was prepared in
® = Registered Trademark
© Pfizer Australia Pty Ltd