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Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this “starvation response” is triggered, and what can inhibit it.

15 Dec 2022

Researchers unravel the molecular mechanisms of steatosis-to-NASH progression

The global prevalence of nonalcoholic fatty liver disease (NAFLD) is estimated to be > 25% and will continue to rise.

15 Dec 2022

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Researchers from the Neurobiology of miRNA team coordinated by Davide De Pietri Tonelli at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) has discovered the correlation between a class of small RNA molecules, piRNAs, and brain inflammation.

15 Dec 2022

Study discovers four genes linked to increased risk of suicidal thoughts and behaviors

A large study of military members led by researchers at Duke Health and the Durham VA identified four genes that are linked to an increased risk of suicidal thoughts and behaviors.

15 Dec 2022

Researchers discover how segmentation clock genes instruct the tempo of spine formation

One of the most dramatic phases of fetal development occurs as previously unstructured collections of rapidly dividing precursor cells begin forming the embryo's spine.

15 Dec 2022

Radical project aims to develop a new method for commercial production of anti-microbial peptides

THE COVID pandemic has revealed just how delicate our public health is in terms of overcoming infectious diseases and antimicrobial resistance.

15 Dec 2022

Edible plant-based ink could reduce the cost of cultured meat production

Cultured meat (also known as cell-based or lab-grown meat) is a promising, more environmentally friendly alternative to meat produced from traditional livestock farming.

15 Dec 2022

Novel experimental system traces the development and longevity of plasma cells

Just as a fire department mobilizes in response to a reported fire, specialized immune cells in the body mobilize in response to the introduction of foreign substances known as antigens.

15 Dec 2022

Scientists uncover how FoxH1 factor binds to specific points in the genome

Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes.

15 Dec 2022

Extraordinary plasticity of the glucocorticoid receptor revealed

Glucocorticoids —such as cortisone— are among the most widely used anti-inflammatory drugs, and are used to treat asthma, psoriasis, organ transplantation and even COVID-19.

15 Dec 2022

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

WNT messenger proteins are crucial for a variety of cellular functions. A specific WNT messenger can increase muscle mass and improve regeneration in skeletal muscle.

14 Dec 2022

Study reveals limited effects of longevity treatments on the aging process

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

14 Dec 2022

Severity of COVID-19 in men may be due to the loss of Y chromosome

Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells.

14 Dec 2022

Research maps the evolution and natural selection of E. coli bacteria

Antibiotic resistance, when infection-causing bacteria evolve so they are no longer affected by typical antibiotics, is a global concern.

14 Dec 2022

Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

Researchers have characterised prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease – from its beginning to the point of androgen independence, where the tumour no longer responds to hormone deprivation therapy.

14 Dec 2022

NIH's All of Us Research Program begins returning personalized health-related DNA results to participants

The National Institutes of Health's All of Us Research Program has begun returning personalized health-related DNA results to more than 155,000 participants, with reports detailing whether participants have an increased risk for specific health conditions and how their body might process certain medications.

13 Dec 2022

Specific bacteria in the bladder may indicate who is more prone to recurrent UTIs

Researchers at The University of Texas at Dallas have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found that estrogen may play a role in reducing that susceptibility.

13 Dec 2022

Life Science News

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Researchers unravel the molecular mechanisms of steatosis-to-NASH progression

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Study discovers four genes linked to increased risk of suicidal thoughts and behaviors

Researchers discover how segmentation clock genes instruct the tempo of spine formation

Radical project aims to develop a new method for commercial production of anti-microbial peptides

Edible plant-based ink could reduce the cost of cultured meat production

Novel experimental system traces the development and longevity of plasma cells

Scientists uncover how FoxH1 factor binds to specific points in the genome

Extraordinary plasticity of the glucocorticoid receptor revealed

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

Study reveals limited effects of longevity treatments on the aging process

Severity of COVID-19 in men may be due to the loss of Y chromosome

Research maps the evolution and natural selection of E. coli bacteria

Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

NIH's All of Us Research Program begins returning personalized health-related DNA results to participants

Specific bacteria in the bladder may indicate who is more prone to recurrent UTIs

'Cellular glue' opens the door to building tissues and organs

Scientists identify molecules in mucus that can block cholera infection

Report makes recommendations clarifying the ethics and oversight of chimeric research

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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