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Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

University of Liverpool signs option agreement with BARD1 for type 3C diabetes test

The University of Liverpool has signed a two year option agreement with the Australian diagnostics company, BARD1 Life Sciences Ltd (ASX: BD1), for a type 3c diabetes (T3cDM) blood test. The test uses patented technology developed by researchers in the University of Liverpool's Institute of Systems, Molecular and Integrative Biology.

7 Jul 2021

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

7 Jul 2021

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

What if the COVID-19 virus could be used against itself? Researchers at Penn State have designed a proof-of-concept therapeutic that may be able to do just that. The team designed a synthetic defective SARS-CoV-2 virus that is innocuous but interferes with the real virus's growth, potentially causing the extinction of both the disease-causing virus and the synthetic virus.

7 Jul 2021

NYUAD researchers unlock an epigenetic code that allows liver regeneration

NYU Abu Dhabi researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate.

6 Jul 2021

Scientists unravel how cell death is initiated on a molecular level

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors.

6 Jul 2021

Scientists construct nano-scale borate bioactive glass with improved wound healing effects

Recently, with the help of a steady-state strong magnetic field experimental device, scientists constructed nano-scale borate bioactive glass (Nano-HCA@BG), which can effectively reduce the biological toxicity of borate bioglass, improve the biocompatibility of the glass, and promote the effect of borate bioglass on skin repair.

6 Jul 2021

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

Researchers from Skoltech and the Mental Health Research Center have found 22 lipids in the blood plasma of people with schizophrenia that were associated with lower symptom improvement over time during treatment.

6 Jul 2021

Comprehensive genetic study provides new insights on cleft lip and palate

Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected.

6 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Scientists discover pathway that sheds new light on brain damage-induced cell division

Most human cells are able to repair damage by dividing at wounds.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Brain cells snap DNA strands in numerous locations to make memories

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

6 Jul 2021

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Plant-based meat substitutes taste and chew remarkably similar to real beef, and the 13 items listed on their nutrition labels - vitamins, fats and protein -- make them seem essentially equivalent.

6 Jul 2021

Study provides a reliable early prognostic biomarker for COVID-19 severity

In a retrospective, multi-centre cohort study conducted by researchers from Nanjing University, Huazhong University of Science and Technology, Jinling Hospital and the Second Hospital of Nanjing, a microRNA-like small RNA encoded by SARS-CoV-2 was identified in the serum of COVID-19 patients, which can be developed as a non-invasive biomarker for stratification of severe patients from mild/moderate ones and for identification of high-risk individuals before clinical manifestation of severe symptoms.

6 Jul 2021

Laboratory manufactured protein spikes mimic key features of SARS-CoV-2 virus

A new international study has found that the key properties of the spikes of SARS-CoV-2 virus which causes COVID-19 are consistent with those of several laboratory-developed protein spikes, designed to mimic the infectious virus.

6 Jul 2021

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.

6 Jul 2021

New method expands view into activity of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

6 Jul 2021

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

Three mutations in the Epsilon coronavirus spike protein dampen the neutralizing potency of antibodies induced by current vaccines or past COVID infections.

6 Jul 2021

Life Science News

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Study unravels the link between chromosomal instability and cellular senescence

University of Liverpool signs option agreement with BARD1 for type 3C diabetes test

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Scientists unravel how cell death is initiated on a molecular level

Scientists construct nano-scale borate bioactive glass with improved wound healing effects

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

Comprehensive genetic study provides new insights on cleft lip and palate

A new method for generating metabolic profiles of single cells

Scientists discover pathway that sheds new light on brain damage-induced cell division

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Brain cells snap DNA strands in numerous locations to make memories

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Study provides a reliable early prognostic biomarker for COVID-19 severity

Laboratory manufactured protein spikes mimic key features of SARS-CoV-2 virus

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

New method expands view into activity of single cells

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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