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ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

The European Laboratory Research & Innovation Group UK and the British Pharmacological Society, announced today that they have formed a strategic alliance.

17 Dec 2019

The Acoustics of the Brain: Random-access 3D Microscopy in Neuroscience

Máté Marosi and Zsolt Iván discuss the use of acousto-optic microscopes to study neural networks in the brain, from cell bodies to dendrites, to tiny spines.

From Femtonics Ltd. 17 Dec 2019

Research finds key reason why brain connectivity goes awry in rare neurodevelopmental conditions

Axons are the long thread-like extensions of neurons that send electrical signals to other brain cells. Thanks to axonal connectivity, our brains and bodies can do all necessary tasks.

16 Dec 2019

Penn researchers track defective sperm epigenome linked to male infertility

One out of eight couples has trouble conceiving, with nearly a quarter of those cases caused by unexplained male infertility. For the past decade, research has linked that infertility to defective sperm that fail to "evict" proteins called histones from DNA during development.

16 Dec 2019

Scientists modify approved cancer drug to develop new antibiotic

Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich and the Helmholtz Center for Infection Research in Braunschweig have now modified an approved cancer drug to develop an active agent against multidrug-resistant pathogens.

16 Dec 2019

Super-resolution localization photoacoustic microscopy can find blocked or burst blood vessels

200 years ago, a doctor from France used a stethoscope for the first time and countless efforts to observe human body have been made since then. Up to now, the best tool that provides anatomical, functional, and molecular information of human and animal is the photoacoustic microscopy.

16 Dec 2019

New concepts for efficient, reliable risk assessment of nanomaterials

From dyes to construction materials, and from cosmetic products to electronics and medicine, nanomaterials are found in many different applications. But what are these materials? "Nanomaterials are defined purely by their size," explains Dr Kristin Schubert from the Department of Molecular Systems Biology at UFZ.

16 Dec 2019

New Method of Creating Synthetic DNA Nanopores

A team has created a synthetic DNA nanopore that can translocate protein-sized macromolecules across lipid bilayers selectively.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Salk researchers uncover new function of mitochondria

Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off molecular alarms when cells are exposed to stress or chemicals that can damage DNA, such as chemotherapy.

15 Dec 2019

Biologists discover that Savannah monitor lizards have hybrid lung structures

Take a deep breath in. Slowly let it out.

15 Dec 2019

New structure for HIV-1 viral shell proposed

The matrix shell of the HIV-1 virus may have a different shape than previously thought, and a newly proposed model has significant implications for understanding how the virus functions, according to a new study by University of Alberta scientists.

14 Dec 2019

New techniques could help neuroscientists track brain computations

Since the 1950s at least, researchers have speculated that the brain is a kind of computer in which neurons make up complex circuits that perform untold numbers of calculations every second. Decades later, neuroscientists know that these brain circuits exist, yet technical limitations have kept most details of their computations out of reach.

14 Dec 2019

Using new high-resolution imaging to track titin in real time

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into muscle development as well as treating damaged muscles and heart disease.

14 Dec 2019

New study improves understanding of widespread diseases

When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process.

14 Dec 2019

International project to preserve genetic resources of birds

The support is provided by the Russian Foundation for Basic Research and the Science and Innovation in East Asia Consortium. Kazan Federal University's partners are Mahidol University and Kumamoto University.

14 Dec 2019

Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range.

From Revvity 13 Dec 2019

CSIRO researchers find simple way to estimate lifespan of animals

Researchers at CSIRO, Australia’s national science agency, have discovered a simple way to estimate how long a species lives.

13 Dec 2019

GEDmatch joins with forensic genomics firm Verogen

GEDmatch, a pioneer in consumer genealogy, today announced that it has joined with forensic genomics firm Verogen, Inc. in a move that allows the company to ensure ongoing privacy protections and enhance the customer experience for users of its website.

From Verogen, Inc. 13 Dec 2019

Human genetics evidence predictive of drug development success, study shows

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts.

From PLOS ONE 13 Dec 2019