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Lifestyle changes can greatly reduce heart disease risk in people with high genetic risk

Study highlights the significant impact of genetic risk and lifestyle on early- and late-onset cardiovascular diseases, showing that lifestyle improvements can notably reduce CVD risk, especially in high genetic risk individuals.

14 Jul 2024

New 3D model sheds light on amyloid-beta's impact

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have unveiled a pioneering study shedding light on the intricate mechanisms underlying Alzheimer's disease (AD). The study, titled "Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype," represents a significant leap forward in understanding the interplay between amyloid-like structures and neuronal cells.

13 Jul 2024

Antibody-drug conjugate shows preclinical efficacy

A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer."

13 Jul 2024

Study reveals how inflammation weakens muscles during illness

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the brain to the muscles and causes a loss of muscle function.

13 Jul 2024

Common therapies contain different cell types, study finds

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current "one-cell-cures-all" paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients.

13 Jul 2024

New tech aims to create marbling in plant-based meat

One of the challenges of creating realistic-looking and delectable plant-based meat is mimicking the marbled effect of animal fat that many carnivores expect and enjoy.

13 Jul 2024

Study links OCD improvement to brain activity shift

A recent study from Baylor College of Medicine and Texas Children's Hospital has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS), a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, led by led by Drs. Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, Sandy Reddy, and Anthony Allam, was published in Nature Medicine.

13 Jul 2024

Mice experiment mimicking foster care raises ethical concerns

Tom Green County District Court Judge Barbara L. Walther ruled Thursday, July 11, 2024, that Angelo State University must release public records relating to an experiment conducted on dozens of mice that resulted in the animals' unnecessary suffering and death, reportedly to study the impact of the foster care system on human children.

13 Jul 2024

Gene editing silences mutant microRNA, restores hearing in adult mice

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people.

13 Jul 2024

OHStat guidelines emphasize clinically meaningful data in oral health research

The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have announced the publication of revised guidelines for adequately reporting findings from oral health research. Overviews and explanations of the new guidelines, called the "OHStat Guidelines," will be published in an upcoming issue of Journal of Dental Research as part of a collaborative effort with The Angle Orthodontics, Journal of Endodontics, Journal of the American Dental Association, and Journal of Oral Maxillofacial Surgery. Additionally, a companion paper will be published in an upcoming issue of JDR Clinical & Translational Research.

13 Jul 2024

Testing the effectiveness of youth activism as a mental health intervention

Three hundred Black and Latinx teens in Chicago will be recruited to participate in the first clinical trial to measure the potential health benefits of youth-driven racial justice activism. The five-year study, funded by a $3.8 million grant from the National Institute on Minority Health and Health Disparities, will assess whether activism can lower depression symptoms in minoritized teens, as well as alter physiological factors known to be increased with exposure to racism, such as blood pressure and markers of stress and inflammation in the blood.

13 Jul 2024

Revolutionary AI model improves early dementia diagnosis

Cambridge scientists have developed an artificially-intelligent tool capable of predicting in four cases out of five whether people with early signs of dementia will remain stable or develop Alzheimer’s disease.

13 Jul 2024

Groundbreaking mRNA vaccine administered to captive elephant to fight EEHV

Colossal, the de-extinction company, announces that the mRNA vaccine it helped to provide research support and acceleration funding for has been administered to the first elephant in captivity.

13 Jul 2024

Innovative AI diabetes training module gets national recognition

The development of a new artificial intelligence-based tool that supports health professionals caring for people with diabetes has led to national recognition for a Northumbria University researcher and her team.

13 Jul 2024

Mainz Biomed seeks FDA’s Breakthrough Devices Designation for advanced colorectal cancer test

Mainz Biomed N.V., a molecular genetics diagnostic company specializing in the early detection of cancer, announced that it has submitted its application to the U.S. Food and Drug Administration (FDA) requesting Breakthrough Device Designation for its non-invasive Next Generation colorectal cancer (CRC) product including the Company’s novel portfolio of mRNA biomarkers. Subject to the FDA’s review, a Breakthrough Device Designation could significantly accelerate approval.

13 Jul 2024

Almirall's Ebglyss recommended by NICE for NHS atopic dermatitis patients

Almirall S.A., a global biopharmaceutical company dedicated to medical dermatology, announced today that the National Institute for Health and Care Excellence (NICE) has recommended Ebglyss (lebrikizumab) for use in moderate to severe Atopic Dermatitis in the NHS England.

13 Jul 2024

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

A newly defined threshold for the concentration of the cytokine CXCL13 may improve the diagnosis of neuroborreliosis.

13 Jul 2024

Simple measures can help address malnutrition in elderly care

As many as half of all patients admitted to hospital and other healthcare facilities are malnourished. This has serious consequences for the individual in terms of unnecessary suffering, poorer quality of life and mortality.

12 Jul 2024

Priority pathogens selected for wastewater surveillance during Paris 2024 Olympic and Paralympic Games

The study by researchers from the French national public health institute aimed to identify priority pathogens that could be suitable for wastewater surveillance (WWS) during the Paris 2024 Olympic and Paralympic Games taking place from 26 July to 11 August and 28 August to 8 September, respectively.

12 Jul 2024