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Deletion of long non-coding RNA linked to rare neurodevelopmental disorder

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a rare and severe neurodevelopmental disorder that renders them wheelchair-bound, nonverbal and with profound intellectual delays.

24 Oct 2024

How dancing can supercharge your health after 55: Discover why ballroom beats the gym!

Dance programs improve older adults' physical and mental well-being, with ballroom and folk dance showing the most consistent benefits. More inclusive, theory-driven studies are needed to optimize outcomes.

24 Oct 2024

High-sensitivity wastewater surveillance correlates with COVID-19 infections

Wastewater surveillance has gained attention as an effective method for monitoring regional infection trends. In July 2024, the National Action Plan for Novel Influenza, etc. included the regular implementation of wastewater surveillance during normal times, with results to be published periodically in Japan.

24 Oct 2024

Tibetan women’s high-altitude adaptations drive greater reproductive success

Researchers uncover how specific genetic and cardiovascular traits give Tibetan women an edge in surviving and thriving at high altitudes, linking better oxygen delivery to more successful pregnancies.

23 Oct 2024

Deforestation drives a surge in malaria cases in the Amazon

Deforestation in the Brazilian Amazon is linked to a rise in malaria cases, with a 1% increase in deforestation leading to a 6.3% spike in cases the following month. This relationship is strongest in highly forested and indigenous areas.

23 Oct 2024

Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

myeloMATCH program opens enrollment for acute myeloid leukemia and MDS

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to myeloMATCH, a unique portfolio of clinical trials to test precision medicine treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

23 Oct 2024

HER2-postive breast cancer drugs show promise for bile duct cancer treatment

Drugs designed to target HER2-postive breast cancer could also benefit some patients with bile duct cancer, according to results of a patient trial to be presented on Thursday at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain.

23 Oct 2024

3D-printed model created to mimic cancer metastasis

Scientists have created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells.

23 Oct 2024

New guidance released for communities at risk of wildfire health impacts

Chemical Insights Research Institute (CIRI) of UL Research Institutes has joined with UL Standards and Engagement to release new guidance for communities at risk for fires in wildland-urban interface (WUI) areas.

23 Oct 2024

Researchers create mini-brains to study autism and test new treatments

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

23 Oct 2024

Parental leave availability influences young adults' norms on childcare

In research published in the British Journal of Social Psychology, investigators examined the relationship between countries' parental leave policies and young adults' perceptions of social norms for the division of childcare duties between mothers and fathers.

23 Oct 2024

New position statement advocates for permanent standard time in the UK

The British Sleep Society has released a position statement in the Journal of Sleep Research advocating for the abolition of the twice-yearly clock changes in the UK and the restoration of permanent Standard Time (Greenwich Mean Time).

23 Oct 2024

Novel device may rescue people from overdose without bystander help

The opioid epidemic claims more 70,000 lives each year in the U.S., and lifesaving interventions are urgently needed.

23 Oct 2024

Healthy habits in middle age may protect against neurological conditions

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a study published in the October 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Oct 2024

Poor sleep quality linked to increased brain aging in middle age

People in early middle age who have poor sleep quality, including having difficulty falling or staying asleep, have more signs of poor brain health in late middle age, according to a study published in the October 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Oct 2024

Study reveals innovative treatment for narcolepsy-related nightmares

A new Northwestern Medicine study has demonstrated a new way to treat narcolepsy-related nightmares.

23 Oct 2024

Urine RNA analysis shows promise for detecting genitourinary diseases

Early detection is critical when it comes to curing diseases like cancer, but not everyone has easy access to screening tools.

23 Oct 2024

Multiple courses of penicillin antibiotics linked to lower risk of Parkinson's disease

A Rutgers Health study has found that people who took multiple courses of penicillin antibiotics had a modestly lower risk of developing Parkinson's disease, a surprising finding that researchers say highlights the complex relationship between bacteria in the digestive tract and brain health.

23 Oct 2024