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Johnson & Johnson seeks first approval of nipocalimab to treat broadest population living with antibody positive generalized myasthenia gravis

The BLA submission for nipocalimab marks a significant advancement in treating generalized myasthenia gravis, showing improved MG-ADL scores in clinical trials.

From Johnson & Johnson 24 Sep 2024

New insights into the mechanism of autophagy activation

An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged components.

24 Sep 2024

Family physicians in rural hospitals and their impact on cesarean delivery rates

The U.S. is experiencing a maternal health crisis, particularly in rural areas. This issue is compounded by rising rates of severe maternal morbidity and mortality.

24 Sep 2024

"Not just a phase": Fussy eating is mainly influenced by genes and is a stable trait

This research highlights the genetic basis of food fussiness in children, with over 70% of influence from genes, informing strategies for dietary interventions.

24 Sep 2024

Incidence and risk factors of an invasive fungal lung infection among COVID-19 patients

Study reveals 0.4%-2.7% incidence of COVID-19-associated pulmonary aspergillosis in severe patients, highlighting significant mortality risks and risk factors.

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

Extreme temperature deaths expected to surge in US by 2065 due to rising emissions

Severe temperature-related mortality in the US is projected to rise significantly by 2065, necessitating focused interventions for at-risk populations.

24 Sep 2024

Known genes account for most undiagnosed cases of developmental disorders

Scientists have conducted the largest and most diverse study to date on how recessive genetic changes contribute to developmental disorders. They found that most undiagnosed cases that are due to recessive causes are linked to genes we already know about, and suggest a shift in research focus could improve diagnosis rates.

24 Sep 2024

Study reveals how inflammatory immune cells enhance prostate cancer resistance

There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully understood.

24 Sep 2024

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

The Henry Royce Institute has published the Materials for Bioelectronics in Healthcare Strategy and Action Plan a comprehensive report that aims to help future-proof the UK’s bioelectronics for healthcare sector through materials innovation.

24 Sep 2024

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Launching today, Landmark is a groundbreaking three-year research programme that aims to understand Parkinson’s in unprecedented detail. The project brings together Parkinson’s UK, Imperial College London, GSK, Novartis, Roche and UCB for the first time, and has been made possible by a founding gift of £4 million from the Gatsby charitable foundation.

24 Sep 2024

FIRS urges global leaders to combat air pollution and lung disease

Seven million deaths annually are attributed to air pollution-related illnesses like COPD, lung cancer and respiratory infections. The Forum of International Respiratory Societies (FIRS), calls on global leaders to intensify efforts to combat air pollution, a leading cause of lung disease and death worldwide.

24 Sep 2024

New AI approach enhances cardiovascular risk assessment

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial.

24 Sep 2024

Lack of awareness contributes to under-reporting of adverse drug reactions

Around 75% of Australians have experienced a bad reaction to a medication, but fewer than half have reported it to a doctor or the Therapeutic Goods Administration (TGA), a new survey has found.

24 Sep 2024

Inadequate staffing in surgical wards linked to adverse outcomes

A new paper in the British Journal of Surgery, published by Oxford University Press, shows that nursing shortages result in longer hospital stays and worse patient outcomes, including higher mortality.

24 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

Age-related differences in financial decision-making and social influence

Older people are more likely to be influenced by the impulsive financial preferences of others than their younger counterparts, according to a new study.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Simple intervention can prevent lifelong disability in premature babies

Giving women at risk of premature birth a simple magnesium sulphate infusion (or 'drip') can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

24 Sep 2024

Wastewater surveillance detects influenza and H5 viruses from human and animal sources

Wastewater surveillance reveals influenza A and H5 subtype detections, providing critical insights into public health risks from both human and animal sources during the ongoing HPAI A(H5N1) outbreak.

24 Sep 2024

Medical News

Johnson & Johnson seeks first approval of nipocalimab to treat broadest population living with antibody positive generalized myasthenia gravis

New insights into the mechanism of autophagy activation

Family physicians in rural hospitals and their impact on cesarean delivery rates

"Not just a phase": Fussy eating is mainly influenced by genes and is a stable trait

Incidence and risk factors of an invasive fungal lung infection among COVID-19 patients

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Extreme temperature deaths expected to surge in US by 2065 due to rising emissions

Known genes account for most undiagnosed cases of developmental disorders

Study reveals how inflammatory immune cells enhance prostate cancer resistance

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

Groundbreaking project seeks to illuminate the complexities of Parkinson's

FIRS urges global leaders to combat air pollution and lung disease

New AI approach enhances cardiovascular risk assessment

Lack of awareness contributes to under-reporting of adverse drug reactions

Inadequate staffing in surgical wards linked to adverse outcomes

New drug combo shows promise for deeper remission in chronic leukemia

Age-related differences in financial decision-making and social influence

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Simple intervention can prevent lifelong disability in premature babies

Wastewater surveillance detects influenza and H5 viruses from human and animal sources

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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