Multiple study data on Agendia's MammaPrint, BluePrint, and ColoPrint assays to be presented at 2010 ASCO

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Agendia, a world leader in molecular cancer diagnostics, today announced that researchers from Agendia and leading academic centers in the U.S. and Europe will present data from multiple studies concerning Agendia's assays MammaPrint(R), BluePrint(TM), and ColoPrint(TM) at the American Society of Clinical Oncology Annual Meeting, June 4 - 8, 2010, at McCormick Place in Chicago. MammaPrint, the company's lead product, is the only FDA-cleared breast cancer recurrence test. FDA clearance requires clinical and analytical validation and full transparency to ensure patient safety issues are addressed. The company anticipates launching its prognostic colon cancer test ColoPrint in late 2010.

The study results underpin the broad predictive and prognostic power of MammaPrint and highlight prospective and independently validated data on ColoPrint. Visitors can meet the Agendia team in booth #18018 and study results will be discussed at the following sessions:

Breast Cancer

Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract #10615 Substratification of 70-gene high-risk breast cancers with a validated 80-gene molecular subtyping profile F. de Snoo, B. Chan, P. Roepman, R. A. Bender, A. Glas Time: 8:00 AM - 12:00 PM Location: S Hall A2

Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract # 540 Gene signatures as predictors of response to neoadjuvant chemotherapy (NCT) with docetaxel, doxorubicin, cyclophosphamide (TAC), or AC and nab-paclitaxel (nab-P) and carboplatin plus or minus trastuzumab in patients (pts) with stage II-III and inflammatory breast cancer (IBC) G. Somlo, P. H. Frankel, L. Vora, S. Lau, T. H. Luu, L. Kruper, J. Yim, Y. Yen, F. de Snoo, R. A. Bender Time: 2:00 PM - 6:00 PM Location: S Hall A2

Date: Saturday, June 5, 2010 POSTER PRESENTATION - Abstract # 561 Evaluation of the 70-gene prognosis MammaPrint signature for the prediction of prognosis of breast cancer independently from histologic grade M. Knauer, E. J. Rutgers, S. Mook, J. Wesseling, L. J. van 't Veer Time: 2:00 PM - 6:00 PM Location: S Hall A2

Date: Monday, June 7, 2010 POSTER DISCUSSION - Abstract # 1520 Effect of screening on the detection of good and poor prognosis breast cancers Y. Shieh, L. Esserman, E. J. Rutgers, M. Knauer, V. Retel, S. Mook, A. Glas, S. C. Linn, F. E. van Leeuwen, L. van't Veer Time: 2:00 PM - 6:00 PM / 5:00 PM - 6:00 PM (discussion in E451b) Location: E450b Colon Cancer

Date: Monday, June 7, 2010 POSTER PRESENTATION - Abstract # TPS199 The PARSC trial, a prospective study for the assessment of recurrence risk in stage II colon cancer (CC) patients using ColoPrint R. Salazar, J. Marshall, L. Stork-Sloots, I. Simon, M. Lutke Holzik, J. Tabernero, J. J. Van Der Hoeven, F. Bibeau, R. Rosenberg Time: 8:00 AM - 12:00 PM Location: S Hall A2

Date: Tuesday, June 8, 2010 POSTER DISCUSSION - Abstract # 3513 Independent validation of a prognostic genomic profile (ColoPrint) for stage II colon cancer (CC) patients R. Rosenberg, M. Maak, U. Nitsche, T. Schuster, B. Kuenzli, M. Snel, I. Simon, K. Janssen, H. Friess Time: 11:00 AM - 12:00 PM Location: S 406 (Vista Room)

SOURCE Agendia B.V.

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