HT, B.Braun partner to launch Adenocaine Hiberplegia syringe pump delivery system

Hibernation Therapeutics USA, LLC (HT) has partnered with B. Braun Medical Inc. (B.Braun) to introduce an innovative, low-cost syringe pump delivery system for the administration of its patented Adenocaine^® Hiberplegia™ solution, the world's first non-depolarizing cardioplegia.

“and we are collecting additional data to better understand the clinical benefit of the Adenocaine® cardioplegia.”

For the first time, cardiac surgeons at The University of Kansas Hospital (KUMED), Kansas City, KS, USA successfully administered Adenocaine^® Hiberplegia™ solution using the B.Braun Perfusor^® Space syringe pump to aid in the arrest and protection of the heart during open heart surgery. "In our initial clinical cases, we have observed improved cardioprotection in some very difficult cases," stated Gregory F. Muehlebach, MD at KUMED, "and we are collecting additional data to better understand the clinical benefit of the Adenocaine^® cardioplegia."

Adenocaine^®'s polarizing patented formulation has shown superior myocardial protection and improved outcomes in preclinical studies and physicians are observing similar results during clinical use, in comparison to standard high potassium depolarizing cardioplegia. According to HT's CSO and James Cook University Professor Geoffrey P. Dobson: "The Adenocaine^® technology places the heart in a more 'natural' state of suspended animation similar to that of a hibernating animal, making cardiac surgery safer for the patient, more predictable for the surgeon and economically compelling for hospitals and other purchasers of health care."

"By incorporating the B.Braun Perfusor^® Space pump with its custom Adenocaine^® drug library, clinicians can easily integrate the delivery of Adenocaine^® into any existing cardioplegia delivery system and at any blood:cardioplegia ratio the perfusionist prefers," said David C. Field, CEO for HT. "This user-friendly, cost-effective syringe pump delivery system now makes the Adenocaine^® solution available and affordable to any hospital."