Study compares effects of weight loss induced by gastric bypass and banding on metabolic response

Obesity is associated with insulin resistance and type 2 diabetes, both of which can be significantly improved by weight loss. Gastric bypass and adjustable gastric banding are two bariatric surgery techniques that are frequently used to effect weight loss in obese patients, but it is unclear if the two procedures produce different outcomes.

In this issue of the Journal of Clinical Investigation, researchers led by Samuel Klein at the University of Washington School of Medicine in St. Louis compared the effects of 20% weight loss induced by either gastric bypass or adjustable gastric banding on metabolic response. They found that patients had different metabolic responses after eating, but both procedures equally improved insulin sensitivity and glucose tolerance. The researchers concluded that weight loss itself is primarily responsible for the therapeutic effects of gastric bypass and adjustable gastric banding in non-diabetic obese adults.



  1. Vince Vince United States says:

    Samuel Klein is at Washington University in St. Louis, not the University of Washington, which is in Seattle.

  2. Mikki0806 Mikki0806 United States says:

    Gastric bypass cost prevents me from undergoing the surgery. It is very expensive and I am considering a safer and inexpensive solution which is better than gastric bypass surgery: Roca Labs costs only $640 compared to $12,000 gastric bypass surgery cost. Anyway, gastric bypass NO surgery sound better. But, I am not sure how good Roca Labs is....

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