Study evaluates the effect of smoking status on disease outcomes in ulcerative colitis

Because smokers are less likely to develop ulcerative colitis (UC), a type of inflammatory bowel disease, patients with UC may be tempted to start smoking to lessen their symptoms. Researchers found no beneficial effects of smoking, however, in a nationwide study that included 6,754 patients with UC.

In the Alimentary Pharmacology & Therapeutics study, smokers and never-smokers with UC had similar outcomes with respect to flares, medication use, hospitalizations, and colon surgery. Also, smoking cessation did not worsen the course of disease in patients.

We did not find any benefits of smoking in ulcerative colitis. We hope our study will give people with ulcerative colitis the confidence to avoid smoking and thereby improve their health in general," said

Lead author Jonathan Blackwell, BMBS, St. George's Healthcare NHS Trust and St. George's University, in London

Source:
Journal reference:

Blackwell, J. et al. (2019) The impact of smoking and smoking cessation on disease outcomes in ulcerative colitis: a nationwide population‐based study. Alimentary Pharmacology & Therapeutics. doi.org/10.1111/apt.15390.

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