Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Psychological traits may uncover why Alzheimer’s biology differs between patients

In 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex. Neuroticism and loneliness were associated with molecular progression, while purpose in life showed subtype-specific inverse associations, suggesting psychological traits may align with Alzheimer’s biology beyond conventional neuropathology.

22 Jun 2026

Engineered CAR-T cells offer potential rheumatoid arthritis cure

For the 18 million people living with rheumatoid arthritis, disease management currently means a lifetime of injections-a reality that new research from Tsinghua University may soon begin to change.

22 Jun 2026

Study links genes and sleep habits to Alzheimer's risk

New research from Edith Cowan University (ECU) has discovered an important link between our genes and sleep habits, suggesting they work together to influence early brain and cognitive changes associated with Alzheimer's Disease, long before symptoms appear.

22 Jun 2026

AI discovers hidden antibiotic candidates inside disease-causing prions

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

19 Jun 2026

Poll reveals gaps in brain health awareness among older adults

Nearly all Michiganders age 50 and over say it's very important to keep their brains healthy as they grow older, a new poll finds.

18 Jun 2026

Key Alzheimer's protein actively protects neurons from nuclear damage

Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD).

17 Jun 2026

USC study reveals nuanced Alzheimer's genetic risk in Hispanic populations

Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC analyzed brain imaging and clinical data from more than 17,000 participants across five major aging and Alzheimer's disease studies.

17 Jun 2026

Blood proteins reveal which aging cells may raise disease risk

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16 Jun 2026

Retinal photographs may reveal early Alzheimer's disease risk

Often called "the window to the soul," the eyes may also offer clues about something less poetic but just as important: the health of the brain.

16 Jun 2026

Study investigates whether obesity accelerates brain aging

Scientists have long known that being obese increases the risk of dementia and Alzheimer's disease. What remains unclear is how that risk develops in the brain.

15 Jun 2026

Blood-based indicator assesses organ age to predict disease risk

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

15 Jun 2026

Lab trials prove copper therapy enhances cognitive function and spatial learning

Monash University researchers have found in laboratory experiments that a drug which delivers copper to the brain significantly reduces toxic Alzheimer's proteins and improves long-term spatial memory.

15 Jun 2026

The cerebellum may help aging brains stay sharper

A large MRI study of more than 47,000 adults found that cerebellar aging is uneven, with posterior association regions and some motor-related areas showing steeper age-related changes. Larger cerebellar volumes were linked to better cognitive performance, supporting a threshold-reserve model in which the cerebellum may help sustain cognition before Alzheimer’s pathology becomes widespread.

11 Jun 2026

A hidden immune pathway may help explain why Alzheimer’s inflammation persists

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.

11 Jun 2026

Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration

The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, neuronal stress, blood-brain barrier integrity, and type I interferon signaling. The review highlights why selective, context-dependent modulation of cGAS-STING could help treat neurodegenerative diseases, while preserving its essential roles in antiviral defense and tumor surveillance.

10 Jun 2026

Low blood pressure shows strongest link to Alzheimer's disease

Numerous types of cardiovascular disease and CVD risk factors were linked to a higher risk of Alzheimer's disease, with low blood pressure showing the strongest connection, according to a new analysis published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Jun 2026

Common joint supplement may accelerate Alzheimer's disease progression

New research has found an association between taking glucosamine, a popular over-the-counter supplement used for joint pain, and a higher likelihood of progressing from mild cognitive impairment to Alzheimer's disease.

9 Jun 2026

Protein repair defects linked to hidden heart failure

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed in patients with idiopathic dilated cardiomyopathy (IDCM ).

9 Jun 2026

Brazil launches genetic screening project for prospective parents

In the coming weeks, the Human Genome and Stem Cell Research Center (HUG-CELL) will begin recruiting participants for the "Our Genes" project.

8 Jun 2026

Blocking immune pathway slows Huntington disease in mouse models

Huntington disease is a rare, inherited brain disorder that progressively destroys nerve cells, leading to worsening movement, cognitive and psychiatric symptoms.

8 Jun 2026