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New antibody delivery system boosts Alzheimer's treatment in mice

A newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer's disease, researchers report.

7 Aug 2025

Personalizing endometrial cancer prevention through diet and lifestyle

This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.

7 Aug 2025

Mechanical stretching boosts stem cell therapy for diabetic wounds

Chronic wounds, especially those caused by diabetes, are notoriously difficult to heal. These wounds are characterized by prolonged inflammation, impaired collagen production, and poor tissue regeneration.

7 Aug 2025

Copper oxide scaffolds show promise in treating traumatic brain injury

Traumatic brain injury (TBI) remains one of the leading causes of disability worldwide. Recent research has developed a novel electrospun scaffold loaded with copper oxide (CuO@PG), which aims to restore copper homeostasis and modulate inflammation in TBI.

7 Aug 2025

Multifunctional hydrogel offers new hope for diabetic wound healing

Diabetes is a global epidemic, and its complications—particularly chronic wounds—are both debilitating and costly.

7 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

Genetic markers could help prevent age-related frailty

Novel genetic insights into frailty highlight potential early predictors, aiding in the prevention of age-related decline and improving health outcomes.

7 Aug 2025

KAIST researchers link placental inflammation to childhood allergies

It is already well-known that when a mother experiences inflammation during pregnancy, her child is more likely to develop allergic diseases.

7 Aug 2025

Sugarcoating hides cellular RNA from the immune system

To our immune system, naked RNA is a sign of a viral or bacterial invasion and must be attacked. But our own cells also have RNA.

6 Aug 2025

Mediterranean diet delivers gut health benefits for expectant mothers

A Mediterranean diet during pregnancy significantly alters the maternal gut microbiome, increasing beneficial bacteria, while a mindfulness-based stress reduction program shows more limited effects. Neither intervention affected the vaginal microbiome, and the clinical significance of these changes requires further study.

6 Aug 2025

Immune aging drives the progression of type 2 diabetes

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.

6 Aug 2025

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

As a chronic condition, rheumatoid arthritis (RA) can't be cured, so treatment focuses on managing the disease and controlling its progression. Although current treatments help control RA symptoms in most people, they cannot prevent the onset of RA or painful flare-ups.

6 Aug 2025

Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but emerging evidence positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.

6 Aug 2025

New tool offers a more precise way to assess stroke risk in people with atrial fibrillation

Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a leading cause of stroke.

6 Aug 2025

Smart wound patch detects healing progress and infection risk

RMIT's Bluetooth-enabled flexible sensor patch monitors wound healing, detecting biomarkers and vital signs without dressing removal for improved patient care.

6 Aug 2025

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

Metabolite patterns reveal potential for COPD population screening

The possibility of having a tool that facilitates population screening for Chronic Obstructive Pulmonary Disease (COPD) is getting closer.

5 Aug 2025

Early immunotherapy shows promise for treating anti-IgLON5 disease

Researchers ask physicians to consider anti-IgLON5 disease if certain symptoms are present, as the only promising approach is early treatment.

5 Aug 2025

Spear Bio announces strategic partnership with Bio-Techne to accelerate the deployment of its next-generation immunoassay technology

Spear Bio, a biotechnology company pioneering homogeneous ultrasensitive immunoassay technology, is pleased to announce a strategic distribution partnership with Bio-Techne Corporation, a global leading provider of innovative reagents, instruments, and solutions for life-science research and clinical diagnostics.

From Spear Bio 5 Aug 2025

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes.

4 Aug 2025