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New experiments reveal how viruses initiate translation of genetic material into proteins

Infectious viruses come in many shapes and sizes and use slightly different attack mechanisms to make humans and animals sick.

25 Sep 2020

Researchers develop 'Trojan horse' approach to destroy cancer cells

Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found.

23 Sep 2020

ALS and FTLD result from reduced transportation of messenger RNA

The lack of protein TDP-43 in two neurodegenerative diseases is shown to prevent neuron growth via failed transport of RNA and subsequent absence of protein synthesis in axons

23 Sep 2020

Light therapy is safe and can benefit patients with TBI, shows study

Light therapy is safe and has measurable effects in the brain, according to a pioneering study by researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH).

23 Sep 2020

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an interdisciplinary research group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have been awarded Intra-CREATE grants from the National Research Foundation Singapore to help support research on retinal biometrics for glaucoma progression and neural cell implantation therapy for spinal cord injuries.

22 Sep 2020

NIH expands clinical trials to evaluate convalescent plasma as a treatment for COVID-19

Two randomized, placebo-controlled clinical trials funded by the National Institutes of Health (NIH) are expanding enrollment to further evaluate convalescent plasma as a treatment for patients hospitalized with COVID-19.

22 Sep 2020

Discovering a molecule that could interfere with SARS-CoV-2 replication

In this interview, News-Medical speaks to Stepan Nersisyan about his discovery of a molecule that could replicate SARS-CoV-2.

22 Sep 2020

Social contacts increase again despite coronavirus

At the beginning of the month, 60 percent still restricted themselves in this regard. At the same time, the proportion of people concerned about the impact of the virus on their social relationships fell to 15 percent.

22 Sep 2020

New national research and training hub at UW-Madison could transform medicine

A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.

22 Sep 2020

A cost-effective scalable production of SARS-CoV-2 RBD in yeast

A new study by the Argentinian AntiCovid Consortium and published in the preprint server bioRxiv* in September 2020 reports on the successful characterization of the conformation and stability of the SARS-CoV-2 spike protein receptor-binding domain (RBD) in two different cell systems. This may help to accelerate the development of vaccines and neutralizing antibodies.

21 Sep 2020

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

A recent study reveals how the non-structural protein 1 (NSP1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a crucial role in inhibiting the host cell protein synthesis but simultaneously facilitating the viral protein synthesis.

21 Sep 2020

Researchers identify a compound that inhibits growth of schwannomas

Schwannomas are tumors of the peripheral nervous system, which often occur in the genetic disease neurofibromatosis type 2. The research group of Prof. Dr. Helen Morrison at the Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, identified a compound that inhibits the growth of such tumors and improves nerve function.

21 Sep 2020

Study identifies new regions of positive selection in SARS-CoV-2

Based on structural modeling of ribonucleic acid (RNA) and proteins, the researchers from Duke University argue that newly identified regions of positive selection in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely affect species-specific RNA instead of protein function – improving our understanding of the molecular mechanisms responsible for highly unique biological properties of this virus.

20 Sep 2020

NIA awards $4.6 million to establish USC-Buck Nathan Shock Center

The University of Southern California Leonard Davis School of Gerontology and the Buck Institute for Research on Aging have received a five year, $4.6 million National Institute on Aging award to jointly establish a Nathan Shock Center of Excellence in the Basic Biology of Aging.

18 Sep 2020

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity.

17 Sep 2020

Study uncovers new markers present on melanoma tumors

A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.

16 Sep 2020

Study identifies a cell-cleaning system that is key to keeping a healthy heart

Researchers of the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a cell-cleaning system that is key to keeping a healthy heart.

15 Sep 2020

African swine fever does not pose health risks to humans

The ASF pathogen is a virus which infects domestic pigs and wild boar and which leads to a severe, often lethal, disease in these animals. It is transferred via direct contact or with excretions from infected animals, or through ticks.

15 Sep 2020

CERN and CHUV team up to develop conceptual design of innovative radiotherapy facility

Geneva and Lausanne. CERN and the Lausanne University Hospital, in Switzerland, are collaborating to develop the conceptual design of an innovative radiotherapy facility, used for cancer treatment.

15 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020