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Researchers identify potential new drug target for treating Barth syndrome

In a Nature Metabolism paper published today, researchers from the University of Pittsburgh detail a potential new target and a small-molecule drug candidate for treating Barth syndrome, a rare, life-threatening and currently incurable genetic disease with devastating consequences.

23 Nov 2023

MRI scans reveal distinct brain changes in people with long COVID

People with long COVID exhibit patterns of changes in the brain that are different from fully recovered COVID-19 patients, according to research being presented next week at the annual meeting of the Radiological Society of North America.

22 Nov 2023

Study finds among outpatients with mild to moderate COVID-19, treatment with fluvoxamine does not reduce duration of symptoms

Researchers investigate the effects of high-dose fluvoxamine among patients with mild-to-moderate COVID-19.

22 Nov 2023

AI and synthetic patients could make early diagnosis of chronic fatigue syndrome more feasible

Between 17 and 24 million people worldwide suffer from chronic fatigue syndrome, a deeply debilitating and difficult-to-diagnose condition.

21 Nov 2023

Novel 3D-printed implant could revolutionize infection control in surgery

A novel surgical implant developed by Washington State University researchers was able to kill 87% of the bacteria that cause staph infections in laboratory tests, while remaining strong and compatible with surrounding tissue like current implants.

20 Nov 2023

Simple soap solution could be a game-changer in the fight against malaria

Could the solution to the decades-long battle against malaria be as simple as soap? In a new study published in PLOS Neglected Tropical Diseases, scientists at The University of Texas at El Paso have made a compelling case for it.

17 Nov 2023

AGA guideline recommends biomarkers for Crohn's disease management

The American Gastroenterological Association (AGA) released a new evidence-based guideline recommending the use of blood and stool-based biomarkers to help manage Crohn's disease, a type of inflammatory bowel disease (IBD).

17 Nov 2023

Circadian rest-activity patterns may signal frailty risk in older adults

Brigham researchers found an association between alterations in circadian rest-activity rhythms and risk of frailty incidence in older adults.

16 Nov 2023

Study reveals acupuncture and massage as effective pain management in advanced cancer

In a clinical trial, acupuncture and massage therapy significantly reduced pain, fatigue, and insomnia, enhancing quality of life in advanced cancer patients over 26 weeks.

16 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Self-perception of health influences physical activity levels in older adults with arthritis

People with arthritis who report more negative feelings about how they are aging tend to get less physical activity and perceive themselves as less healthy, according to a new study by researchers at Hospital for Special Surgery (HSS) and Weill Cornell Medicine.

14 Nov 2023

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

In a JAMA Network Open study, researchers found no evidence of neuroinflammation or blood-brain barrier dysfunction in cerebrospinal fluid markers of individuals with post-COVID-19 condition and neuropsychiatric symptoms compared to controls. The study, which assessed cytokines, chemokines, and neuroinflammation markers, suggests that persistent central nervous system immune activation may not be the primary driver of neurological long COVID symptoms.

13 Nov 2023

Allergies linked to heightened risk of long COVID, new review suggests

Systematic review indicates that pre-existing allergic conditions like asthma and allergic rhinitis may be linked to an increased risk of developing long COVID. Despite some evidence, the certainty remains low due to potential biases and confounding factors, highlighting the need for more rigorous research to determine the impact of these allergies on prolonged COVID-19 symptoms.

9 Nov 2023

People with multiple sclerosis could benefit from a low-fat diet

New research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, could benefit from a low-fat diet to improve the fatigue that's a debilitating, and often-underappreciated, symptom of the condition.

9 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023