Fatigue News and Research

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Squid™ Full Range Pipette: Reduce pipette changes, bench clutter, and calibration burden

The Squid Full Range Pipette covers 1–1000 µL in one device, reducing pipette changes, bench clutter, calibration burden, and workflow fatigue.

From DeNovix Inc. 22 May 2026

How screen time, stress, and nicotine trap young adults in poor sleep

Among the younger part of the population, sleep problems, anxiety, and depression are widespread and growing issues.

22 May 2026

Could blocking inflammation help treat difficult-to-treat depression?

A small proof-of-concept RCT found that tocilizumab, an IL-6 receptor blocker, showed a non-significant but clinically suggestive pattern of improvement in difficult-to-treat depression linked to low-grade inflammation. The study found that baseline hs-CRP, rather than IL-6, may help identify patients most likely to respond, supporting larger trials of immune-targeted depression care.

22 May 2026

Study supports routine childhood screening for type 1 diabetes

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care.

21 May 2026

Researchers discover how overpopulation reduces fertility

Scientists have reported it for decades: Overpopulation can impair reproduction.

21 May 2026

Phase two clinical trial demonstrates dramatic mobility gains in children with severe fibrous dysplasia

Fibrous dysplasia is a rare skeletal disorder in which normal bone is gradually replaced by weak fibro-osseous tissue, leading to fractures, pain, deformities, and severe mobility impairment. In many patients, diseased bone tissue produces excessive amounts of fibroblast growth factor-23 (FGF23), a hormone that causes phosphate loss through the kidneys.

21 May 2026

Oral AD109 improves sleep apnea severity but tolerability remains a challenge

AD109, an investigational once-daily oral combination of aroxybutynin and atomoxetine, significantly improved airway obstruction and oxygenation in adults with mild-to-severe obstructive sleep apnea who could not use PAP therapy. However, symptom improvements did not clearly differ from placebo, and about one in five AD109 recipients discontinued treatment due to adverse events.

21 May 2026

Anti-inflammatory drug tocilizumab shows promise for difficult-to-treat depression

Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomised controlled clinical trial, published in JAMA Psychiatry today [20 May].

20 May 2026

Higher ferritin threshold could detect childhood iron deficiency much earlier

Many cases of iron deficiency in school-aged children could be diagnosed earlier, according to a new study published in Blood Red Cells & Iron, a journal of the American Society of Hematology (ASH).

20 May 2026

Stem cell infusions improve symptoms in butterfly skin disease

The intravenous infusion of mesenchymal stem cells from family donors is safe and improves symptoms such as pruritus (itching), sleep disturbances, and fatigue associated with Recessive Dystrophic Epidermolysis Bullosa (RDEB), popularly known as "butterfly skin".

18 May 2026

Health experts outline symptoms and risks of shipboard hantavirus

It's one of the cruisegoer's biggest fears: a contagious disease outbreak at sea.

18 May 2026

Preclinical models map genetic changes behind multiple sclerosis nerve damage

More than 1 million people across the United States live with multiple sclerosis (MS), a disease that affects the brain, optic nerves and spine.

18 May 2026

Perimenopause nearly doubles women’s odds of poor heart health

Perimenopause is linked to worsening cardiovascular health, with significant declines in lipid and glucose scores, emphasizing the need for early assessment.

15 May 2026

Identifying the methodology gap that prevents treatment of infection-triggered chronic diseases

Thousands of Americans develop chronic persistent symptoms-such as fatigue, cognitive difficulties ("brain fog"), and other debilitating issues-each year following acute infections from Lyme disease, COVID-19, and other pathogens. Efforts to identify causes and produce treatments have failed. However, 16 leading researchers think they know part of the problem: study design.

14 May 2026

Scientists identify methylphenidate as an effective tool for combating chronic cancer-related fatigue

A new meta-analysis in the May 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants-a class of medication that increases dopamine and norepinephrine availability in the brain-can provide meaningful relief for cancer-related fatigue.

14 May 2026

New research identifies the hidden stressors of modern digital classrooms

An international research team, led by the University of Warwick and the Universitat Autònoma de Barcelona (UAB), in collaboration with Friedrich-Alexander-Universität, recently published a scoping review in the journal Cogent Education.

14 May 2026

Colbopasvir plus sofosbuvir achieves high cure rates in chronic hepatitis C

In this real‑world multicenter study (Wenzhou, China), 113 chronic hepatitis C patients received colbopasvir (60 mg) + sofosbuvir (400 mg) daily for 12 weeks. Overall SVR12 was 99.1% (112/113). SVR12 was 100% for genotypes 3a, 3b, 6a, and compensated cirrhosis, 93.3% for genotype 1b, and 90% for HBV co‑infection.

14 May 2026

Study challenges structural explanation for gut symptoms in hEDS patients

A study, led by experts at the University of Nottingham, has found that persistent and distressing upper gut symptoms experienced by people with hypermobile Ehlers-Danlos syndrome (hEDS), are not due to structural problems with the gullet (esophagus), as previously assumed.

13 May 2026

Maternal workplace exposures may increase autism risk in children

Mothers who work in jobs where they are frequently exposed to toxic chemicals or experience high stress have higher odds of having a child with autism spectrum disorder (ASD), suggest the findings of original research published online in the journal Occupational & Environmental Medicine.

12 May 2026

Researchers map the brain histamine system to understand mental health

New research, from King's College London and the University of Porto, has mapped the histamine system in the brain. Histamine, a molecule more commonly associated with allergies, plays a separate but poorly understood role in brain function.

12 May 2026