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Why female athletes need injury prevention rules built for women, not men

This International Olympic Committee consensus synthesised evidence from over 600 studies to develop 56 injury prevention recommendations tailored to female, woman and girl athletes. It concludes that reducing injury risk requires a whole sports system approach that integrates training, policy, environment and culture, not exercise alone.

8 Dec 2025

Timing of genetic mutation dictates childhood leukemia aggressiveness

A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes: it depends on when in development the mutation first occurs.

8 Dec 2025

AI method could help clinicians accurately identify brain tumors and radiation necrosis

While targeted radiation can be an effective treatment for brain tumors, subsequent potential necrosis of the treated areas can be hard to distinguish from the tumors on a standard MRI.

8 Dec 2025

UCI MIND secures major funding for new Alzheimer's research facility

With a $50 million lead gift from the Quilter family and approximately $30 million in new commitments, the University of California, Irvine's Institute for Memory Impairments and Neurological Disorders will begin planning to build a state-of-the-art research and care facility to enhance its position as a global leader in Alzheimer's disease and related dementias research and patient care.

8 Dec 2025

Simple blood and urine tests could spare febrile infants from more invasive procedures

New evidence from a six-country study led by the Montreal Children's Hospital and Children's National Hospital shows simple blood and urine tests could spare many young infants with fevers from more invasive procedures.

8 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T cell therapy for multiple myeloma share a common immune root cause, are associated with high rates of death unrelated to cancer relapse-primarily infection-and may be avoidable.

8 Dec 2025

PTSD may be linked to accelerated brain aging among World Trade Center responders

Researchers from the Icahn School of Medicine at Mount Sinai have found that post-traumatic stress disorder (PTSD) may be linked to accelerated brain aging among World Trade Center (WTC) responders involved in rescue and recovery operations after the 9/11 terrorist attacks.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

High temperatures and heat waves may lead to delays in early childhood development

Climate change-including high temperatures and heat waves-has been shown to pose serious risks to the environment, food systems, and human health, but new research finds that it may also lead to delays in early childhood development.

8 Dec 2025

Standard UK road crossing times may be unrealistic for older people with limited mobility

Road crossings need to slow down to allow people with mobility issues and older pedestrians enough time to use them, research has indicated.

8 Dec 2025

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.

7 Dec 2025

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Pirtobrutinib, a non-covalent Bruton tyrosine kinase (BTK) inhibitor, met the primary endpoint for non-inferiority in terms of overall response rate in the first head-to-head comparison with ibrutinib, a covalent BTK inhibitor.

7 Dec 2025

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy.

7 Dec 2025

New trial shows major survival gains with epcoritamab added to standard R2 therapy

In a new trial, patients with follicular lymphoma had a significantly higher response to treatment and a nearly 80% reduction in the risk of death or disease progression if they received epcoritamab in addition to the standard second-line regimen versus the standard regimen alone.

7 Dec 2025

Human researchers still outperform AI when it comes to writing trustworthy systematic reviews

Human researchers outperformed large language models across all major stages of systematic review preparation, particularly in study selection, synthesis, and final manuscript drafting. While LLMs demonstrated speed and partial accuracy in early screening and data extraction, they could not independently produce high-quality, guideline-compliant systematic reviews.

7 Dec 2025

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.

7 Dec 2025

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation.

7 Dec 2025

Many families of children with leukemia face significant financial hardship during treatment

Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.

7 Dec 2025

Quality improvement project dramatically boosts iron deficiency screening in pregnancy

Within a year of initiation, a multidisciplinary project to improve screening and treatment for iron deficiency in pregnancy resulted in a sixfold rise in screening rates for iron deficiency in pregnant patients, a 20-fold rise in the number of intravenous (IV) iron infusions, and a significant improvement in median hemoglobin levels.

7 Dec 2025

Education News and Research

Why female athletes need injury prevention rules built for women, not men

Timing of genetic mutation dictates childhood leukemia aggressiveness

AI method could help clinicians accurately identify brain tumors and radiation necrosis

UCI MIND secures major funding for new Alzheimer's research facility

Simple blood and urine tests could spare febrile infants from more invasive procedures

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

PTSD may be linked to accelerated brain aging among World Trade Center responders

JAX wins $30 million contract to create computational "digital twins" of the human heart

High temperatures and heat waves may lead to delays in early childhood development

Standard UK road crossing times may be unrealistic for older people with limited mobility

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

New trial shows major survival gains with epcoritamab added to standard R2 therapy

Human researchers still outperform AI when it comes to writing trustworthy systematic reviews

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

Many families of children with leukemia face significant financial hardship during treatment

Quality improvement project dramatically boosts iron deficiency screening in pregnancy

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