Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Nuclera and leadXpro partner to accelerate structure-based drug design for complex membrane proteins

Nuclera, the biotechnology company enabling rapid access to high-quality proteins and leadXpro, a specialist in structure-based drug discovery for membrane proteins, today announced a scientific partnership.

17 Feb 2026

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs.

13 Feb 2026

Parkinson's-related weight loss reflects a failure of the body's energy-producing pathways

Weight loss is a well-recognized but poorly understood non-motor feature of Parkinson's disease (PD). Many patients progressively lose weight as the disease advances, often alongside worsening motor symptoms and quality of life.

13 Feb 2026

Tahoe Therapeutics generates the largest single-cell atlas ever using INTEGRA Biosciences automated pipetting technologies

Tahoe Therapeutics - a biotech start-up based in San Francisco, California - is creating the largest ever atlas of cell-chemical interactions to inform drug discovery. Combining automated pipetting systems from INTEGRA Biosciences, Parse Biosciences' Evercode™ single-cell RNA sequencing (scRNA-seq) products, and its own proprietary AI algorithms, the company already has several drug discovery programs running in parallel across multiple cancer types, and is expanding into other therapeutic areas.

12 Feb 2026

Carterra launches industry’s first 48-channel HT-SPR platform for advanced label-free biomolecular screening and characterization

Carterra Inc., the leading provider of technologies enabling high-throughput biology, today announced the launch of the Carterra Vega™ High-Throughput Surface Plasmon Resonance (HT-SPR) instrument.

From Carterra Inc. 11 Feb 2026

Novel computational framework developed for real-time, personalized heart rate variability monitoring

Real-time and early detection of minute changes in the functioning of the cardiovascular system is crucial for managing critically ill patients, such as newborns and older adults, and can significantly affect their outcomes.

10 Feb 2026

SPT Labtech and Bellbrook Labs introduce high-throughput screening platform for cancer research

SPT Labtech, a global leader in the design and development of automated instrumentation and consumables for life sciences, and BellBrook Labs, a pioneer in high-throughput screening (HTS) assay tools, today announced a collaboration to advance cancer research.

9 Feb 2026

Synthace collaborates with Charles River to offer the global pharma industry more robust, faster and cost-effective assays

Synthace, the leader in software and services for assay development, today announced a collaboration with Charles River Laboratories International, Inc. (Charles River), a leading global drug discovery, development, testing, and manufacturing solutions provider.

9 Feb 2026

AI model accelerates antibody production and clone selection

As instigators of immunity, monoclonal antibodies are marvels of modern medicine, lab-made proteins that can treat cancers, autoimmune diseases, and many other conditions.

9 Feb 2026

Chronic brain compression triggers neuron death through multiple pathways

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord.

9 Feb 2026

Sustainable pharmacy initiatives needed to reduce environmental harm from medicines

The group of the EHU - University of the Basque Country is proposing various initiatives designed to reduce the presence of medicines in the environment and, consequently, their effects on human health.

6 Feb 2026

New DNA-based vaccine scaffolds boost targeted immune responses to HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Revvity unveils new high-impact discovery platforms and showcases recent innovations at SLAS2026

Revvity, Inc. announced the launch of multiple new discovery platforms and technologies at SLAS2026, which are designed to accelerate high-throughput drug discovery workflows.

5 Feb 2026

Study identifies genetic fingerprint of neuropathic pain neurons

Researchers from The University of Texas at Dallas and their international colleagues have determined the molecular signature of human sleeping - or silent - nociceptors: sensory neurons that are unresponsive to touch or pressure yet are key culprits in neuropathic pain.

4 Feb 2026

Drug Discovery News and Research

Further Reading

Nuclera and leadXpro partner to accelerate structure-based drug design for complex membrane proteins

Thermodynamic insights into histamine H1 receptor ligand binding

Parkinson's-related weight loss reflects a failure of the body's energy-producing pathways

Tahoe Therapeutics generates the largest single-cell atlas ever using INTEGRA Biosciences automated pipetting technologies

Carterra launches industry’s first 48-channel HT-SPR platform for advanced label-free biomolecular screening and characterization

Novel computational framework developed for real-time, personalized heart rate variability monitoring

SPT Labtech and Bellbrook Labs introduce high-throughput screening platform for cancer research

Synthace collaborates with Charles River to offer the global pharma industry more robust, faster and cost-effective assays

AI model accelerates antibody production and clone selection

Chronic brain compression triggers neuron death through multiple pathways

Sustainable pharmacy initiatives needed to reduce environmental harm from medicines

New DNA-based vaccine scaffolds boost targeted immune responses to HIV

Revvity unveils new high-impact discovery platforms and showcases recent innovations at SLAS2026

Study identifies genetic fingerprint of neuropathic pain neurons

Advancing brain microphysiological systems for in vitro neurotoxicity and cognitive function testing

Engineering-driven startups at ASU advance biomedical innovation

Evosep launches IQ/OQ protocols for the Evosep Eno System at WCBP 2026

CDD European Life Science Community Meeting

Study offers a practical strategy to enhance effectiveness of immune checkpoint inhibitors

Brain protein CUL5 protects neurons by clearing toxic tau clumps

ELRIG Drug Discovery: Poster Sessions eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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