Infertility News and Research

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Infertility primarily refers to the biological inability of a person to contribute to conception. Infertility may also refer to the state of a woman who is unable to carry a pregnancy to full term.

Scientists discover on/off gene switches that could revolutionize personalized medicine

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. These findings could pave the way for more precise diagnostics and personalized therapies across cancers, immune, skin, and metabolic diseases.

22 Jun 2025

Histone modification involved in chromosome and spindle stabilization in mouse oocytes

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation.

20 Jun 2025

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of diseases, particularly cancers.

20 Jun 2025

Scientists find hundreds of genes that behave like light switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

AMA endorses resolution to expand access to anti-obesity medications

The American Medical Association (AMA) House of Delegates today passed the Endocrine Society's resolution to improve access to anti-obesity medications.

11 Jun 2025

Bipartisan obesity bill gains support from Endocrine Society

The Endocrine Society today endorsed the introduction of the bipartisan Treat and Reduce Obesity Act (TROA) in the Senate.

5 Jun 2025

Global female infertility rates surge, hitting women in their late 30s hardest

Researchers analyzed global data from 1990 to 2021 and found that over 110 million women worldwide were affected by infertility, with a significant rise in age-standardized rates. The study highlights shifting trends, with the greatest burden among women aged 35–39, and projections showing further increases in age-standardized rates by 2050.

22 May 2025

Blood filtration may offer new hope for removing microplastics from the body

Researchers report the first evidence that therapeutic apheresis, a blood-filtration technique, can remove microplastic- and nanoplastic-like particles from humans with ME/CFS. While promising, further studies are needed to quantify removal and assess clinical benefits.

21 May 2025

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired testicular function through oxidative stress and autophagy dysregulation. These findings raise concerns about the reproductive risks of high sucralose intake and its persistent presence in the environment.

19 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Infertility in women linked to higher risk of heart disease

Women who experience infertility are more likely to develop heart and blood vessel conditions later in life, with younger women and those who undergo fertility treatments at a greater risk.

11 May 2025

Study reveals phthalate exposure harms early sexual development in children

Maternal exposure to phthalates during pregnancy is linked to shorter anogenital distance in 3-year-old boys, a marker of impaired sexual development. Girls showed similar outcomes from their own postnatal exposure, highlighting the lasting hormonal risks of environmental pollutants.

10 May 2025

Low phosphate levels may help explain male infertility, study finds

Men with fertility problems were significantly more likely to have low blood phosphate levels, a mineral essential for energy and reproductive function. Researchers found lower phosphate was linked to poorer sperm motility, suggesting a possible pathway for new fertility treatments.

10 May 2025

New molecule offers hope for chlamydia treatment

Researchers at Umeå University, Sweden, and Michigan State University, USA, have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health.

8 May 2025

Can your diet affect fertility? Gut-linked dietary score reveals surprising risk pattern

A cross-sectional study of over 3,000 U.S. women found a non-linear link between a gut microbiota-based dietary index (DI-GM) and infertility. Risk decreased with healthier diets but unexpectedly rose beyond a certain threshold score.

4 May 2025

Heat triggers sperm activation for fertilization in mammals

In mammals - including us humans - sperm are surprisingly picky about temperature, thriving best in conditions a few degrees cooler than normal body temperature.

2 May 2025

Addressing the urgent health and environmental threat from endocrine disrupting chemicals

Taking place on 14 May 2025, in Copenhagen and online, the event will bring together leading European scientists, policymakers and civil society to address the urgent health and environmental threat from endocrine disrupting chemicals (EDCs).

2 May 2025

Better sleep, BMI, and glucose control lower female infertility odds

A new study using NHANES data found that higher Life’s Crucial 9 (LC9) scores, reflecting better cardiovascular and mental health, were linked to lower odds of female infertility. However, adding depression to the LE8 framework did not significantly improve its predictive value.

29 Apr 2025

Ferritin levels unrelated to infertility and metabolic health risks in women with PCOS

Women with polycystic ovary syndrome (PCOS) tend to have higher average ferritin levels compared to control subjects, but this does not seem to have a significant impact on their fertility or metabolic health.

28 Apr 2025

COVID-19 lowers sperm count and motility, new study confirms

SARS-CoV-2 infection is linked to significant declines in sperm quality, including reduced sperm count, motility, and increased DNA fragmentation, as shown in both cross-sectional and longitudinal observations.

24 Apr 2025