Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Long-term calorie restriction can slow cellular markers of brain aging

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage.

25 Nov 2025

How immune signals activate brain circuits to drive sickness-induced social withdrawal

MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection.

25 Nov 2025

Prefrontal cortex modulates visual and motor regions based on internal feelings

Vision shapes behavior and, a new study by MIT neuroscientists finds, behavior and internal states shape vision.

25 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline.

25 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Gut nervous system controls intestinal barrier and allergy risk

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.

25 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Diesel exhaust particles can impair microglial functions

Diesel exhaust particles can disturb the function of human brain immune cells, known as microglia, according to a recent study led by the University of Eastern Finland.

25 Nov 2025

Using a prebiotic after traumatic brain injury may help reduce impulsive behavior

Using a prebiotic to influence bacterial activity in the gut after a traumatic brain injury may help reduce impulsive behavior, one of the common symptoms to follow a moderate blow to the head, a new study in rats suggests.

25 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

In a new JNeurosci paper, Tian-Ming Gao and colleagues, from Southern Medical University, explored how adenosine triphosphate (ATP) signaling relates to depression and anxiety using male mice. ATP is a molecule that not only provides energy but also supports communication between neurons.

25 Nov 2025

Neuroscientists detect five broad phases of brain structure in the average human life

Neuroscientists at the University of Cambridge have identified five "major epochs" of brain structure over the course of a human life, as our brains rewire to support different ways of thinking while we grow, mature, and ultimately decline.

25 Nov 2025

Focused ultrasound combined with chemotherapy improves survival in glioblastoma patients

Patients with the deadliest form of brain cancer, glioblastoma, who received MRI-guided focused ultrasound with standard-of-care chemotherapy had a nearly 40 percent increase in overall survival in a landmark trial of 34 patients led by University of Maryland School of Medicine (UMSOM) researchers.

24 Nov 2025

Genetic factors behind impulsive choices tied to metabolic and mental health

Researchers from University of California San Diego have identified 11 genetic regions linked to delay discounting - the tendency to prefer smaller, immediate rewards over larger, delayed ones - shedding new light on how impulsive decision-making relates to both mental and physical health.

24 Nov 2025

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Swallowing difficulties, or dysphagia, affect up to 80% of people with Parkinson's disease and can lead to serious complications, including malnutrition, aspiration and reduced quality of life.

24 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Arginine reduced amyloid beta aggregation in vitro and in both Drosophila and AppNL-G-F mouse models of Alzheimer’s disease, leading to fewer dense-core plaques and improved behavior. The study provides preclinical evidence that oral arginine may modulate amyloid pathology, although high dosing requirements and model limitations constrain human translation.

24 Nov 2025

Can diet calm early memory problems? Anti-inflammatory Mediterranean eating shows promise

Older women who follow a strongly anti-inflammatory Mediterranean diet report far fewer subjective memory complaints than those who do not. The AnMED pattern outperforms both traditional Mediterranean and MIND diets, showing a clear advantage for protecting early cognitive symptoms.

24 Nov 2025

Gut neurons control immunity attack or repair

Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the immune system should go into attack mode or start repairing tissue.

24 Nov 2025

Brain News and Research

Further Reading

Long-term calorie restriction can slow cellular markers of brain aging

How immune signals activate brain circuits to drive sickness-induced social withdrawal

Prefrontal cortex modulates visual and motor regions based on internal feelings

Genetic signals reveal why erectile dysfunction develops and who is most at risk

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Infection-related hospital stays linked to higher risk of developing dementia

Gut nervous system controls intestinal barrier and allergy risk

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Diesel exhaust particles can impair microglial functions

Using a prebiotic after traumatic brain injury may help reduce impulsive behavior

Scientists uncover how brain enzyme OTULIN controls tau expression

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

Neuroscientists detect five broad phases of brain structure in the average human life

Focused ultrasound combined with chemotherapy improves survival in glioblastoma patients

Genetic factors behind impulsive choices tied to metabolic and mental health

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

New analysis shows one in two people in the U.S. live with neurological conditions

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Can diet calm early memory problems? Anti-inflammatory Mediterranean eating shows promise

Gut neurons control immunity attack or repair

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

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