Cell Proliferation News and Research

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Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Study reveals dual role of TEAD proteins in neural development

Scientists at St. Jude Children’s Research Hospital found that, in neural development, the same set of proteins involved in cellular self-renewal can also facilitate differentiation with the right binding partner.

20 May 2025

Diabetes drug shows potential in slowing prostate cancer progression

A drug used to treat type 2 diabetes may also be effective in slowing the progression of prostate cancer.

20 May 2025

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

18 May 2025

Clinical trial against breast cancer explores the potential anti-tumor role of denosumab

Science and society collaboration is essential for scientific progress, especially in the health and biomedical fields where basic researchers, clinicians and patients are involved, as shown by the initial results of D-BIOMARK.

16 May 2025

Exploring the role of RNA binding proteins and circular RNAs in cancer

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

12 May 2025

Review spotlights MYC as a multidimensional therapeutic target in cancer

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional therapeutic target.

12 May 2025

RANBP2 identified as key regulator in the progression of multiple solid tumors

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies.

12 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Study reveals colonic inflammation as the trigger for beta cell growth in obesity

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway that leads to increased insulin production.

9 May 2025

Diabetes drug shows promise for treating prostate cancer

An international team of scientists led by the Medical University of Vienna has identified similarities in the mechanisms of diabetes and cancer: as the researchers show, the protein PPARγ, which is central to the regulation of metabolic processes, can also influence the growth of prostate cancer cells.

6 May 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.

30 Apr 2025

New compounds identified as inhibitors of DNA topoisomerase 1

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA.

29 Apr 2025

lncRNAs shape the tumor microenvironment and drive cancer development

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

24 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor progression to help prevent colorectal cancer (CRC). Evidence suggests adequate vitamin D levels and supplementation reduce CRC risk and improve outcomes.

21 Apr 2025

New therapeutic frontiers in the management of achondroplasia

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular mechanisms and therapeutic interventions for achondroplasia, the most common form of genetic dwarfism.

20 Apr 2025

Molecular drivers and emerging treatments in anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.

20 Apr 2025

Cell Proliferation News and Research

Gut bacteria and diet found to affect cancer treatment outcomes

Study reveals dual role of TEAD proteins in neural development

Diabetes drug shows potential in slowing prostate cancer progression

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Clinical trial against breast cancer explores the potential anti-tumor role of denosumab

Exploring the role of RNA binding proteins and circular RNAs in cancer

Review spotlights MYC as a multidimensional therapeutic target in cancer

RANBP2 identified as key regulator in the progression of multiple solid tumors

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

HER3 reemerges as a key driver of cancer progression and therapy resistance

Targeting METTL3 may offer new hope for oral cancer treatment

Study reveals colonic inflammation as the trigger for beta cell growth in obesity

Diabetes drug shows promise for treating prostate cancer

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

New compounds identified as inhibitors of DNA topoisomerase 1

lncRNAs shape the tumor microenvironment and drive cancer development

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

New therapeutic frontiers in the management of achondroplasia

Molecular drivers and emerging treatments in anaplastic thyroid cancer

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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