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Genetic keys to COVID-19 vaccine response unlocked

A genome-wide association study in the U.K. Biobank reveals genetic factors influencing IgG serostatus against SARS-CoV-2, highlighting the role of HLA class II genes in variable immune responses to COVID-19 vaccines.

7 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.

4 Jan 2024

Gut microbiome plays a role in immune response to mRNA COVID vaccines

Researchers from Karolinska Institutet in Sweden have discovered that the gut microbiome can influence how well people respond to mRNA COVID vaccines.

4 Jan 2024

Simple technique boosts antibody delivery for treating brain diseases

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

3 Jan 2024

Are pan-coronavirus vaccines an achievable goal in providing broad protection against human coronaviruses?

The current achievements in the development of a pan-coronavirus vaccine.

3 Jan 2024

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Study evaluates the impact of hybrid immunity on SARS-CoV-2 antibody levels in Canadian adults, revealing that hybrid immunity, combining vaccination and recovery from infection, significantly reduces COVID-19 morbidity and mortality.

2 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

Catenane magic: Boosting protein stability and resilience with interlocking rings

This study is led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University).

29 Dec 2023

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Researchers have identified a previously unrecognized class of antibodies-;immune system proteins that protect against disease-;that appear capable of neutralizing multiple forms of flu virus.

21 Dec 2023

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

UVA Alzheimer's study pinpoints how tau protein damages brain cells

University of Virginia Alzheimer's researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

20 Dec 2023

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Amidst a backdrop of industry-wide hurdles like inflation, talent scarcities, and stringent regulatory landscapes, Nona Biosciences is showing great promise as an emerging global leader in biotechnology.

From Nona BioSciences 19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

B cell deficiency is a common condition that can result either from immunosuppressant drugs used to treat autoimmune disease or certain cancers -; such as rituximab (RTX) -; or from natural immune deficiency.

18 Dec 2023

Maternal microbiome's pivotal role in shaping fetal and neonatal immune systems during pregnancy

Review in Nature Reviews Gastroenterology and Hepatology explores how the maternal microbiome during pregnancy influences the immune systems of the mother, fetus, and neonate, highlighting its impact on long-term health outcomes and the development of pregnancy complications.

18 Dec 2023

Two proteins in the blood could predict dengue severity

Scientists and clinicians at Nanyang Technological University, Singapore (NTU Singapore) and the National Centre for Infectious Diseases (NCID) have identified two compounds - sST2 and suPAR - in the blood of dengue patients that could determine if a patient is at risk of severe dengue in the early phases of the disease.

18 Dec 2023

Antibodies News and Research

Genetic keys to COVID-19 vaccine response unlocked

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Gut microbiome plays a role in immune response to mRNA COVID vaccines

Simple technique boosts antibody delivery for treating brain diseases

Are pan-coronavirus vaccines an achievable goal in providing broad protection against human coronaviruses?

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Exploring the global health challenge of hepatitis D

Catenane magic: Boosting protein stability and resilience with interlocking rings

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

Brain injury markers found in the blood months after COVID-19 infection

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Shedding new light on the hidden organization of the cytoplasm

UVA Alzheimer's study pinpoints how tau protein damages brain cells

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

Maternal microbiome's pivotal role in shaping fetal and neonatal immune systems during pregnancy

Two proteins in the blood could predict dengue severity

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