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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

Investigational drug shows promise in treating rare blood disease in fetuses

Data from a new investigational drug that could alter the standard treatment for a rare blood disease suggests it has the potential to delay or prevent anemia and the need for intrauterine blood transfusions in babies who are at high risk for the condition, known as Hemolytic Disease of the Fetus and Newborn (HDFN).

7 Aug 2024

New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Breakthrough study highlights ATM activation by DNA single-strand breaks

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Yogurt with probiotics and honey boosts gut bacteria but no digestive or cognitive benefits

A study in The Journal of Nutrition found that yogurt with B. animalis and honey increases probiotic levels but doesn't affect digestion, cognition, or mood.

6 Aug 2024

Beckman Coulter Life Sciences and Illumina Accelerate Oncology Research with Launch of TruSight Oncology 500 DNA/RNA Application

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From Beckman Coulter Life Sciences - Flow Cytometry 6 Aug 2024

Reduced folate intake enhances metabolic plasticity in aged mice

Folate fortification of staple foods has long been practiced in many countries.

6 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Upper respiratory microbiome shows age, sex, and lifestyle impacts, study finds

A Dutch study analyzed the upper respiratory tract microbiome across various age groups, finding significant associations between microbial composition, age, sex, and lifestyle factors like smoking and antibiotic use.

5 Aug 2024

Rapid, noninvasive tool tracks neurons and biomolecules activated in the brain by psychedelic drugs

Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs.

5 Aug 2024

Breakthrough study identifies mechanisms behind glucocorticoid resistance in pediatric B-ALL

Josep Carreras Leukaemia Research Institute B-ALL is the most common paediatric cancer and, over the years and thanks to a very effective treatment based on glucocorticoids, its 5-year survival rates have reached 85% and beyond.

5 Aug 2024

Unraveling the role of neo-sex chromosomes in mitigating sexual conflict

Researchers from Tokyo Metropolitan University have taken a big step in solving the mystery around why animals evolve sex chromosomes.

4 Aug 2024

Study provides novel insights into the molecular mechanisms of melanoma progression

Cong Peng et al., at Department of Dermatology, Xiangya Hospital, Central South University, China, conducted a study titled "NETO2 promotes melanoma progression via activation of the Ca²⁺/CaMKII signaling pathway" that investigates the role of Neuropilin and tolloid-like 2 (NETO2) in melanoma, a deadly form of skin cancer.

2 Aug 2024

How machine learning is accelerating research in structural biology

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human.

2 Aug 2024

Decreasing folate intake can support healthier metabolisms in aging animal models

In a study published in Life Science Alliance, Texas A&M AgriLife Research scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

2 Aug 2024

Mast cells found to capture and employ neutrophils during allergic reactions

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system.

2 Aug 2024

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

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DNA News and Research

Further Reading

Review of fasting-mimicking diets in cancer treatment

Investigational drug shows promise in treating rare blood disease in fetuses

New treatment boosts pluripotent stem cell production in mice

Breakthrough study highlights ATM activation by DNA single-strand breaks

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

METRNL protein identified as key player in cancer progression

Study advances understanding of complex neurological disorder

Yogurt with probiotics and honey boosts gut bacteria but no digestive or cognitive benefits

Beckman Coulter Life Sciences and Illumina Accelerate Oncology Research with Launch of TruSight Oncology 500 DNA/RNA Application

Reduced folate intake enhances metabolic plasticity in aged mice

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Upper respiratory microbiome shows age, sex, and lifestyle impacts, study finds

Rapid, noninvasive tool tracks neurons and biomolecules activated in the brain by psychedelic drugs

Breakthrough study identifies mechanisms behind glucocorticoid resistance in pediatric B-ALL

Unraveling the role of neo-sex chromosomes in mitigating sexual conflict

Study provides novel insights into the molecular mechanisms of melanoma progression

How machine learning is accelerating research in structural biology

Decreasing folate intake can support healthier metabolisms in aging animal models

Mast cells found to capture and employ neutrophils during allergic reactions

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

Understanding the DNA Damage Response in Innate Immunity eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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