Neurodegenerative Diseases News and Research

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Study could pave the way for simple blood test to diagnose Alzheimer's disease

In a landmark study of Hispanic and Latino adults, researchers at University of California San Diego School of Medicine have identified a link between self-reported cognitive decline and blood-based biomarkers, which could pave the way for a simple blood test to help diagnose Alzheimer's disease and related dementias.

8 Sep 2025

Former New Zealand rugby players face higher risk of dementia and Alzheimer’s

Former male high-level rugby players in New Zealand have a 22 percent increased risk of developing Alzheimer's and other dementias later in life compared to men in the general population, according to new research from the University of Auckland.

4 Sep 2025

Study finds possible molecular connection between air pollution and Lewy body dementia risk

A team of researchers found there is a possible molecular connection between air pollution and an increased risk of developing Lewy body dementia.

4 Sep 2025

Understanding the role of paraventricular thalamic nucleus in bipolar disorder pathophysiology

Bipolar disorder (BD) is a chronic mental health condition characterized by recurrent episodes of depression and mania.

4 Sep 2025

New Mohn Research Center aims to protect the brain and prevent Parkinson’s disease

Backed by NOK 50 million (~USD 5 million) from the Mohn Foundation in partnership with the University of Bergen (UiB) and Haukeland University Hospital, the Center will unite clinicians, neuroscientists, and data experts to understand who is at risk, how disease begins, and how to protect the brain before irreversible damage occurs.

4 Sep 2025

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.

3 Sep 2025

TRIMTECH Therapeutics establishes Scientific Advisory Board

TRIMTECH Therapeutics, a biotech company creating novel, small molecule therapeutics that selectively degrade protein aggregates, to combat neurodegenerative diseases, today announced the formation of its Scientific Advisory Board (SAB).

From TRIMTECH Therapeutics 3 Sep 2025

Researchers reveal how diseases interact at the genetic level

2 Sep 2025

Visualizing lipid transport inside living cells with fluorescence microscopy

Lipid molecules, or fats, are crucial to all forms of life. Cells need lipids to build membranes, separate and organize biochemical reactions, store energy, and transmit information.

29 Aug 2025

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Within the next few years, doctors may be able to spot signs of Alzheimer's disease and other dementias using routine eye exams well before symptoms appear, a new study suggests.

27 Aug 2025

Can diet alone slow brain aging? Scientists say evidence is still too weak

Researchers reviewing evidence in the Annual Review of Nutrition find that healthy dietary patterns may support brain aging, but caution that scientific enthusiasm currently outpaces solid proof. Multidomain strategies combining diet with exercise, cognitive training, and vascular health show greater promise.

25 Aug 2025

Hemoglobin emerges as a natural antioxidant defense in the brain

Did you know the same protein that gives blood its red color and carries oxygen throughout the body is also present inside brain cells? Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked - and potentially game-changing - antioxidant role in the brain.

22 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Blocking brain damage may slow aggressive glioblastoma growth

Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers.

20 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

Discovering the brain’s internal compass through virtual reality

Zhengang Lu and Russell Epstein, from the University of Pennsylvania, led a study to explore how people maintain their sense of direction while navigating naturalistic, virtual reality cities.

18 Aug 2025

RNA quality control protein PELOTA found to slow aging and extend lifespan

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.

18 Aug 2025

New molecule shows promise in treating acetaminophen-induced liver injury

Acetaminophen is one of the most common painkillers and is found in hundreds of different medications. While safe at recommended doses, acetaminophen overdose is the leading cause of acute liver injury in the U.S.

18 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

New discovery in spinal cord neurons offers hope for breathing recovery

Today about 300,000 people nationally living with a spinal cord injury and with respiratory complications being the most common cause of illness and death, according to the Christopher & Dana Reeve Foundation.

13 Aug 2025