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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

New open access tool could accelerate drug discovery

Scientists at Northwestern University have developed the largest open-access resource of its kind to help researchers shave off months of early-stage drug development time by allowing them to better understand diseases and find potential treatments.

12 Jun 2025

Prenatal air pollution exposure related to subtle fetal brain changes

Fetuses more exposed to certain air pollutants show changes in the size of specific brain structures, particularly during the second and third trimesters of pregnancy.

11 Jun 2025

Healthy lifestyle habits may shield aging cells from brain disorders

Stroke and dementia as well as late-life depression are more common in people who have a biomarker of aging called short leukocyte telomere length, according to a study published on June 11, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

11 Jun 2025

Tufts researchers develop dental implant that mimics real tooth function

Each year, millions of people in the U.S. get dental implants as a long-term, natural-looking fix for missing teeth. But traditional implants don't fully mimic real teeth.

11 Jun 2025

Extending imaging uncovers hidden stroke-related blood clots

A groundbreaking clinical trial led by London Health Sciences Centre Research Institute (LHSCRI) and Western University's Schulich School of Medicine & Dentistry may enhance how medical professionals detect hidden blood clots responsible for strokes.

11 Jun 2025

Brain interface restores real-time speech for man with ALS

Researchers at the University of California, Davis, have developed an investigational brain-computer interface that holds promise for restoring the voices of people who have lost the ability to speak due to neurological conditions.

11 Jun 2025

New pilot project shows early success in helping cancer survivors return to work

A new pilot project led by McGill University researchers is showing early success in helping cancer survivors return to work, addressing an aspect of recovery they say is often overlooked.

11 Jun 2025

Memory neurons in rats may explain why forgetting meals leads to overeating

Researchers identify "meal memory" neurons in laboratory rats that could explain why forgetting lunch leads to overeating.

11 Jun 2025

Smelling food triggers fullness through newly found brain pathway

No more hunger after cooking? A newly identified network of nerve cells is responsible, a research group at the Max Planck Institute for Metabolism Research has discovered in mice.

11 Jun 2025

How Parkinson’s disease affects emotion recognition of voices

A new study in Neurodegenerative Diseases looks closely at how Parkinson’s disease can affect something as everyday and essential as recognizing emotion in someone’s voice.

From S. Karger AG 11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

John Oldham redefines the landscape of personality disorders

In a comprehensive Genomic Press Interview published today in Brain Medicine, John M. Oldham, MD, MS, one of psychiatry's most influential architects of personality disorder theory, traces his remarkable journey from frontier medicine roots in Oklahoma to revolutionizing how mental health professionals understand and diagnose personality pathology.

11 Jun 2025

Uncovering the genetic link between type 2 diabetes and brain structure

Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic disorder worldwide. Beyond glucose dysregulation, it exerts significant effects on the central nervous system.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025

Psilocybin rewires the brain for weeks, study finds

Psilocybin induces consistent and sustained changes in brain network connectivity, particularly between the hippocampus and default mode network, as shown using high-resolution fMRI in healthy adults. These neural effects, distinct from those produced by methylphenidate, may underlie the drug’s psychological benefits and were reproducible within individuals over time.

10 Jun 2025