Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

A study led by researchers at the Garvan Institute of Medical Research shows for the first time how a gene called RELA, known to regulate inflammation, also plays an essential role in maintaining normal blood-sugar levels.

14 Jun 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Study provides a treasure trove of information on molecular biology of the immune system

Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system to help treat autoimmune diseases.

5 Jun 2023

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Lupus Therapeutics announced the start of a collaboration to conduct three Phase 3 clinical trials testing an investigational therapeutic ianalumab for systemic lupus erythematosus and lupus nephritis.

2 Jun 2023

Long-term consequences of COVID-19 in patients with inflammatory rheumatic diseases

Studies on the long-term consequences of COVID-19 (long-COVID) in patients with inflammatory rheumatic diseases (iRD) are scarce.

31 May 2023

Burden of autoimmune disease continues to increase over time, research suggests

EULAR – the European Alliance of Associations for Rheumatology – works on a broad spectrum of autoimmune and auto-inflammatory diseases.

31 May 2023

Gene expression signature associated with rapid progression of type 1 diabetes

Researchers from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland, have identified a gene expression signature that can predict the progression of type 1 diabetes.

29 May 2023

Study shows how IgA acts as a "tuner" to keep the immune system in check

IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers.

26 May 2023

The first thousand days of development

Study provides a bird's-eye view of the significant moments of the first thousand days of life.

25 May 2023

Lupus Landmark Study launched to accelerate the development of personalized treatments for lupus patients

The Lupus Research Alliance and its clinical research affiliate Lupus Therapeutics today announced the launch of the Lupus Landmark Study, a groundbreaking observational research study to accelerate the development of personalized treatments for people living with lupus.

24 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Understanding Lupus: an interview with the Garvan Institute

To commemorate World Lupus Day, we spoke to Elissa Deenick, co-lead of the Precision Immunology Program at the Garvan Institute, about the current state of lupus understanding and what needs to happen to make lupus visible.

9 May 2023

Clinicians must broaden their duty of care while treating people with deep-seated trauma

Child protection experts are imploring clinicians to broaden their duty of care to ensure that patients’ hidden trauma is not overlooked by more obvious physical symptoms and illnesses.

8 May 2023

NIH researchers gain new insights on rare immune deficiency

In an 11-year study, researchers at the National Institutes of Health have further characterized idiopathic CD4 lymphocytopenia (ICL), a rare immune deficiency that leaves people vulnerable to infectious diseases, autoimmune diseases and cancers.

4 May 2023

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

24 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin.