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New Canadian guidelines streamline screening for high-risk drinking

An update to Canadian guidance on screening for high-risk drinking and alcohol use provides streamlined recommendations in CMAJ (Canadian Medical Association Journal) that authors hope will make it easier for health care professionals to talk to patients about alcohol use.

4 May 2026

Semaglutide as a promising new treatment for alcohol use disorder

Research indicates semaglutide can significantly decrease alcohol consumption and cravings in individuals with comorbid obesity and alcohol use disorder.

4 May 2026

Study debunks steroid myths, framing creatine as an essential energy-providing molecule

Creatine, a compound often associated with gym-goers and athletes, has long been touted as a performance-enhancing supplement. But beyond the hype, what does science actually reveal about its effects on the body and mind?

4 May 2026

Manuka honey eye drops outperform artificial tears for dry eye relief

A clinical study reveals Manuka honey eye drops significantly improve dry eye symptoms after cataract surgery, outperforming traditional treatments.

1 May 2026

Five-target drug beats GLP-1/GIP therapy in obese diabetic mice

A Nature study reports a single-molecule GLP-1–GIP–lanifibranor quintuple agonist that targets incretin receptor-expressing cells while activating PPARα/γ/δ pathways. In obese and insulin-resistant mice, the compound reduced body weight, food intake, and hyperglycaemia more effectively than semaglutide or GLP-1R–GIPR co-agonism, while remaining a preclinical finding.

30 Apr 2026

GLP-1 drugs reduce risk of major adverse cardiovascular events

New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes and premature death over a sustained period of time.

30 Apr 2026

New CAR T cell design boosts persistence and reduces toxicity

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

30 Apr 2026

New review questions whether vaping consistently helps smokers quit

A new review paper in Nicotine and Tobacco Research, published by Oxford University Press, finds that while research has previously found that vaping is associated with subsequently quitting smoking, that may not always be true.

30 Apr 2026

New research shows weight loss is possible without GLP-1

Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.

30 Apr 2026

From killers to strategists: CAR T cells enter their multifunctional era

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

30 Apr 2026

Metabolic rewiring could help CAR-T cells fight solid tumors

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function.

29 Apr 2026

New hybrid molecule uses Trojan horse approach to treat obesity

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a "door opener" and delivers an additional metabolic modulator specifically into the target cells.

29 Apr 2026

New bioelectronic interface enables long-term vagus nerve stimulation for inflammation

Electrical stimulation of vagus nerve via implantable stimulators can effectively suppress inflammatory responses, offering a novel strategy for treating autoimmune diseases.

29 Apr 2026

UIC researchers develop anti-cancer therapy inspired by bacteria in tumors

Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer tumors.

28 Apr 2026

Why H2N2 flu is back on the pandemic preparedness radar

A historical review in Vaccine warns that global H2N2 immunity has sharply declined since the 1957 Asian influenza pandemic, leaving most people without H2-specific protection if the virus re-emerges. The authors highlight animal reservoirs, waning birth-cohort immunity, and modern H2 vaccine platforms as key priorities for pandemic preparedness.

28 Apr 2026