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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

New discovery could overcome immune therapy failure in ovarian cancer

University of Virginia Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

12 Feb 2025

Vascular changes in brain trauma could trigger Alzheimer’s development

An increased risk of dementia among individuals exposed to brain trauma, traumatic brain injury, has been known for almost a century.

12 Feb 2025

Why generative AI is widening the gender gap in academic research

The productivity gap in research widens as male researchers utilize AI more effectively. Targeted interventions are needed to support female counterparts.

12 Feb 2025

Scientists discover brain mechanism behind nicotine withdrawal

According to the World Health Organization (WHO), over 22% of the global population smokes, with more than 9 million smoking-related deaths reported annually.

12 Feb 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

Study shows a clear causal relationship between gut microbiota and vagal nerve activity

A new study in an animal model provides direct evidence for the role of the vagus nerve in gut microbiome-brain communication, addressing a critical gap in the field.

11 Feb 2025

Air pollution harms cognition just hours after exposure, study finds

New research shows that inhaling polluted air for just an hour can impair cognitive abilities like attention and emotional recognition within four hours, highlighting the urgent need for cleaner air policies.

11 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

Innovative brain tumor model offers hope for personalized cancer treatments

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.

11 Feb 2025

Breakthrough discovery on tau protein opens new paths for Alzheimer’s drug development

A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau.

11 Feb 2025

New method provides accurate measurement of drug permeability across the blood-brain barrier

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from potentially dangerous substances and microbes.

11 Feb 2025

Working after 50 improves health and well-being for older adults

Having a job – whether it's working for someone else or being their own boss – gives older Americans more than just a way to earn money or get health insurance, a new poll finds.

11 Feb 2025

Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment

Researchers develop targeted polymersomes loaded with methotrexate for the treatment of gestational choriocarcinoma,

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Study uncovers a significant presence of manic symptoms in schizophrenia patients

In a notable Genomic Press research report, researchers at the Aristotle University of Thessaloniki have uncovered a significant presence of manic symptoms in patients with schizophrenia spectrum disorders (SSDs), offering valuable insights that could reshape treatment approaches.

11 Feb 2025