Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Paradox suggests reasons why COX-2 inhibitors hurt and help

Laboratory studies at Johns Hopkins have revealed that certain products of the enzymes COX-1 and COX-2 can both protect and damage the brain. The findings, published in the February 2005 issue of the Journal of Neurochemistry, offer tantalizing clues to why drugs like Vioxx and Celebrex, which block COX-2, can ease arthritis but potentially harm the heart and brain.

14 Feb 2005

Key insight into the process of normal synapse development may lead to improved treatment of conditions such as drug addiction and epilepsy

Communication in the brain travels from one nerve cell to another through critical connections called synapses. These neuron-to-neuron junctions form early in brain development, and their construction was thought to be guided by the nerve cells themselves.

13 Feb 2005

Visual recognition begins with categorization

Take a moment and look at a picture near you. What did you see? How long did it take you to understand what was in the image, meaning how long did it take you to realize the green blob was a tree? Or that the orange circle was a piece of fruit? Most likely you assume that it took you no time at all, you just knew.

13 Feb 2005

New way of transporting medicines into the brain

Dutch researcher Corine Visser investigated a new way of transporting medicines into the brain. Her approach made use of an iron transport system located on the blood-brain barrier. The smaller the medicine, the more easily it penetrates the brain.

13 Feb 2005

Ingestion of afterbirth appears to promote maternal behavior in mammals

A behavioral neuroscientist at the University at Buffalo holds that the ingestion of afterbirth by a mother, a feature of pregnancy in nearly all non-human mammals, not only relieves postpartum pain, but optimizes the onset of maternal behavior by mediating the activity of specific opioid activity circuits in the brain.

13 Feb 2005

Researchers show how attention enhances visual perception

The researchers, from NYU's Department of Psychology and Center for Neural Science, found that attending to, or selectively processing information from a given location without directing our eyes to that location, enhances performance in visual tasks as well as the neural activity underlying the processing of ensuing images. The results are published in the latest issue of the journal Neuron.

10 Feb 2005

Sudden emotional stress can result in severe but reversible heart muscle weakness

Shocking news, such as learning of the unexpected death of a loved one, has been known to cause catastrophic events, such as a heart attack.

10 Feb 2005

Sex hormone progesterone metabolite allopregnanolone reduces stress

A steroid hormone released during the metabolism of progesterone, the female sex hormone, reduces the brain's response to stress, according to research in rats by scientists at Emory University School of Medicine, the Yerkes National Primate Research Center and Atlanta's Center for Behavioral Neuroscience.

9 Feb 2005

Chronic nicotine exposure worsens some Alzheimer’s-related brain abnormalities

UCI researchers have determined that chronic nicotine exposure worsens some Alzheimer’s-related brain abnormalities, contradicting the common belief that nicotine can actually be used to treat the disease.

9 Feb 2005

How polychlorinated biphenyls open brain cells to Parkinson's assault

University of Rochester scientists investigating the link between PCBs, pesticides and Parkinson's disease demonstrated new and intricate reactions that occur in certain brain cells, making them more vulnerable to injury after exposures.

9 Feb 2005

Screening for toxoplasmosis for all pregnant women and newborns is necessary

Physicians found that signs, symptoms and identifiable risk factors are absent in more than half of the mothers of infants with congenital toxoplasmosis in a national study of children with this disease.

9 Feb 2005

Inserting corrective genes into the brain to fight Parkinson's disease

An international team of scientists has used gene therapy in two separate studies to renew brain cells and restore normal movements in monkeys and rats with a drug-induced form of Parkinson's disease.

8 Feb 2005

Health risks increase in Guyana with leptospirosis

Leptospirosis has become a health concern in Guyana, as the number of cases continues to rise and 43 people were being treated for suspected cases of the bacterial disease, which is usually caused by exposure to water contaminated with the urine of infected animals.

8 Feb 2005

Research confirms how early-life events shape later physiology

Underscoring the value of good prenatal care, new research suggests that early infection may create a cognitive vulnerability that appears later during stress on the immune system.

8 Feb 2005

Clues to autism's neural basis

In a study that broadens our understanding of the neural basis of social interactions, researchers at Harvard Medical School and the University of Montreal have shown that individuals with autism display abnormal patterns of activity in brain circuits that underlie the understanding of other people's behavior.

7 Feb 2005

Marijuana changes blood flow in the brain

People who smoked marijuana had changes in the blood flow in their brains even after a month of not smoking, according to a study published in the February 8 issue of Neurology, the scientific journal of the American Academy of Neurology.

7 Feb 2005

People with autism may perform unusually well on some tests of visual processing

The researchers found that autistic people were less likely than others to have false memories about images they had seen earlier. The researchers had previously demonstrated this kind of effect with verbal material, but not with visual material.

7 Feb 2005

New way to assess the potentially damaging effects of prenatal drug exposure

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug exposure--a technique that could also be used to monitor a fetus's response to therapeutic drugs--using sophisticated, noninvasive medical imaging tools.

7 Feb 2005

Prions, previously thought to accumulate mainly in the brain can also infect other organs

Prions, infectious proteins associated with bovine spongiform encephalopathy (BSE) or Mad Cow Disease, were previously thought to accumulate mainly in the brain, but Yale and University of Zurich researchers report in Science that other organs can also become infected.

7 Feb 2005

Varicella vaccine is almost 90 percent effective against chickenpox

The varicella vaccine is almost 90 percent effective against chickenpox, but its impact on herpes zoster (shingles) is unknown and needs wider surveillance, Yale School of Medicine researchers write in today's New England Journal of Medicine (NEJM) perspective section.

7 Feb 2005