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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University.

2 Aug 2024

Olympic athletes overcome health challenges to reach the pinnacle of their sport

The athletes have done the training and achieved their dreams, a trip to the Paris Olympics set to begin Friday July 26th.

2 Aug 2024

Researchers identify strategy to design safer opioids

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.

2 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

Vanderbilt to introduce focused ultrasound for treating essential tremor and Parkinson's disease

The movement disorder neurology and neurosurgery team at Vanderbilt University Medical Center is set to add focused ultrasound treatment (FUS) as a new tool in the treatment of essential tremor and Parkinson's disease.

1 Aug 2024

New lab technique captures aging effects in Alzheimer's disease development

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

1 Aug 2024

Fish oil may benefit older adults with genetic Alzheimer's risk

A clinical trial at Oregon Health & Science University suggests that a subset of older adults with a genetic predisposition to Alzheimer's disease may benefit from fish oil supplements.

1 Aug 2024

Single-cell RNA sequencing sheds light on stroke-induced brain damage

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death.

1 Aug 2024

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Researchers assessed cognitive function among rheumatoid arthritis patients with ongoing inflammatory activity.

1 Aug 2024

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, even as people around the world live longer and the number of people with dementia is set to rise dramatically in all countries, according to the third Lancet Commission on dementia prevention, intervention, and care, which is being presented at the Alzheimer's Association International Conference (AAIC 2024).

1 Aug 2024

Scientists capture NMDAR protein's 'twist' motion, key to brain signaling

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These bindings control NMDAR's dance steps. When their routine is over, the NMDAR opens. This open ion channel generates electrical signals critical for cognitive functions like memory.

1 Aug 2024

Anticancer drugs show promise in reducing Alzheimer's dementia risk

Study finds anticancer drugs, specifically antimetabolites and molecular targeted therapies, may reduce the risk of Alzheimer's type dementia but not vascular dementia.

1 Aug 2024

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them.

31 Jul 2024

Salk Institute receives CIRM funding for stem cell research on aging and neurodegeneration

The Salk Institute was awarded $3.6 million by the California Institute for Regenerative Medicine (CIRM), one of the world's largest institutions dedicated to regenerative medicine.

31 Jul 2024

High diastolic blood pressure linked to increased migraine risk in women

Having high blood pressure, specifically high diastolic blood pressure, was linked to a slightly higher odds of ever having migraine in female participants, according to a new study published in the July 31, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

31 Jul 2024

Brain News and Research

Further Reading

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

Olympic athletes overcome health challenges to reach the pinnacle of their sport

Researchers identify strategy to design safer opioids

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

Vanderbilt to introduce focused ultrasound for treating essential tremor and Parkinson's disease

New lab technique captures aging effects in Alzheimer's disease development

Fish oil may benefit older adults with genetic Alzheimer's risk

Single-cell RNA sequencing sheds light on stroke-induced brain damage

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Scientists capture NMDAR protein's 'twist' motion, key to brain signaling

Anticancer drugs show promise in reducing Alzheimer's dementia risk

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

Salk Institute receives CIRM funding for stem cell research on aging and neurodegeneration

High diastolic blood pressure linked to increased migraine risk in women

Study reveals serotonin's role in ependymoma tumor growth

Commonly used anesthetic drug can restore the function of ion channel linked to epilepsy

AI-enhanced EEG analysis paves way for early dementia detection

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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