Therapeutics News and Research

RSS

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Researchers determine atomic interactions that stabilize phase-changing proteins

Most of the well-studied proteins in our bodies are like metal; some can change shape easily, like aluminum foil, and others are rigid, like steel beams, but they typically have a solid, well-defined structure.

2 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

UK charity invests £1 million to develop potential therapeutic for Parkinson's

Charity Parkinson's UK is partnering with NRG Therapeutics Ltd to discover and develop a potential drug that could safeguard dopamine cells that are damaged by Parkinson's and slow down the progression of the condition.

1 Jul 2019

Scientists unravel how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in unraveling the spent proteins.

29 Jun 2019

New strategy may strengthen gut-brain communication

Scientists have developed a strategy that raises the volume of gut-body communication, paving the way for new interventions to improve human health.

28 Jun 2019

Fecal miRNAs could provide clues to early inflammation found in chronic gut conditions

Small molecules found in fecal matter could provide clues to the early inflammation found in chronic gut conditions, such as intestinal bowel disease, and serve as new biomarkers for diagnosis, according to a study led by the Institute for Biomedical Sciences at Georgia State University.

28 Jun 2019

High-fat, low-carbohydrate diet may improve brain function and memory in older adults

In a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins Medicine researchers report that a high-fat, low-carbohydrate diet may improve brain function and memory.

28 Jun 2019

Heat from nanoparticles zaps cancer cells from inside

Oregon State University researchers have come up with nanoclusters that are capable of reaching within tumours that are difficult to reach. The results of this breakthrough in cancer therapeutics were published in a study in the latest issue of the journal ACS Nano.

26 Jun 2019

Quanterix announces agreement to acquire UmanDiagnostics, world’s leading neurofilament light (Nf-l) antibody supplier

Quanterix announce agreement to acquire privately held UmanDiagnostics AB for $22.5 million.

From Quanterix 26 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019

Making Bacterial Infections a Thing of the Past for Chronic Respiratory Conditions

In this interview, Prof. Elborn and Dr. Dixon discuss the issues involving chronic lung conditions such as cystic fibrosis and bacterial respiratory infections.

From Neem Biotech 25 Jun 2019

PhoreMost and C4XD sign neurodegeneration drug discovery collaboration agreement

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, and C4X Discovery Holdings plc, a pioneering drug discovery company, today announced they have signed a neurodegeneration drug discovery collaboration agreement.

From PhoreMost 25 Jun 2019

New blood test could potentially diagnose Alzheimers even before symptoms appear

Doctors may one day be able to diagnose Alzheimer's disease, the most common cause of severe dementia, and monitor a patient's response to treatment by doing a simple blood test.

24 Jun 2019

Study identifies proteins that interact with processes regulating gene p53

Scientists at VCU Massey Cancer Center have discovered that the loss of a protein called DBC1 in breast cancer cells leads to the dysregulation of normal anti-cancer functions, contributing to cancer cell growth and resistance to therapies.

24 Jun 2019

MIT engineers devise new way to create nanoemulsions

MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within another liquid, known as nanoemulsions.

21 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

New chief medical officer appointed for Cancer Research UK’s Centre for Drug Development

Professor Peter Johnson will be the new chief medical officer for Cancer Research UK’s Centre for Drug Development, it was announced today (Tuesday).

19 Jun 2019

FACS-based CRISPR screening shows how Chlamydia bacterium invades host cells

Using FACS-based CRISPR screening, scientists have identified three candidate genes that may facilitate the invasion of Chlamydia trachomatis into host cells.

19 Jun 2019

Therapeutics News and Research

Using popular anticonvulsant drug to thwart inflammation

Researchers determine atomic interactions that stabilize phase-changing proteins

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

UK charity invests £1 million to develop potential therapeutic for Parkinson's

Scientists unravel how cells unfold proteins

New strategy may strengthen gut-brain communication

Fecal miRNAs could provide clues to early inflammation found in chronic gut conditions

High-fat, low-carbohydrate diet may improve brain function and memory in older adults

Heat from nanoparticles zaps cancer cells from inside

Quanterix announces agreement to acquire UmanDiagnostics, world’s leading neurofilament light (Nf-l) antibody supplier

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

Making Bacterial Infections a Thing of the Past for Chronic Respiratory Conditions

PhoreMost and C4XD sign neurodegeneration drug discovery collaboration agreement

New blood test could potentially diagnose Alzheimers even before symptoms appear

Study identifies proteins that interact with processes regulating gene p53

MIT engineers devise new way to create nanoemulsions

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

New chief medical officer appointed for Cancer Research UK’s Centre for Drug Development

FACS-based CRISPR screening shows how Chlamydia bacterium invades host cells

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News