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Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain.

5 Dec 2025

Genetic variant linked to higher heart failure risk in children with myocarditis

A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure.

5 Dec 2025

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.

5 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.

5 Dec 2025

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel sublingual therapy Tonmya has received approval from the U.S. Food and Drug Administration (FDA) - marking the first new drug for Fibromyalgia in more than 15 years.

From Hanson Wade Group - Non-Opioid Pain Therapeutics Summit 5 Dec 2025

Ripple & Bausch’s licensing agreement: What it means in ocular delivery

Ripple Therapeutics, a clinical-stage company developing polymer-free sustained release drug delivery systems, has entered into an evaluation and licensing option agreement with an affiliate of Bausch + Lomb.

From Hanson Wade Group - 4th Ophthalmic Drug Delivery Summit 5 Dec 2025

TRIMTECH Therapeutics appoints Alison Lawton as Chair of the Board

TRIMTECH Therapeutics, a biotechnology company developing novel small molecule therapies that target and degrade protein aggregates associated with neurodegenerative diseases, today announced the appointment of Alison Lawton as Chair of its Board of Directors.

From TRIMTECH Therapeutics 4 Dec 2025

Research says global HIV efforts need renewed funding and focus

As the world marks World AIDS Day on Dec. 1, world-renowned infectious disease expert Anthony Fauci, MD, and his colleague Greg Folkers, MS, MPH, highlight advances made in the treatment and prevention of HIV that could finally end the pandemic, but caution, "History will judge us harshly should we squander this opportunity."

1 Dec 2025

Researchers uncover GFAP’s role in mitochondrial dysfunction

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

1 Dec 2025

Mapping SV2A drug binding offers a path to better epilepsy treatments

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

1 Dec 2025

Advances in screening and therapeutics make lung cancer treatable, survivable

For decades, lung cancer has been associated with stigma, anxiety, and loss. Advances in screening, therapeutics, and survivorship have created a new reality; lung cancer is treatable, survivable, and increasingly understood as a chronic disease for many.

1 Dec 2025

New consortium aims to fast-track breakthroughs against follicular lymphoma

Follicular lymphoma (FL) is the second most frequent subtype of non-Hodgkin lymphoma, a cancer of the immune system. Although the disease is typically incurable, many cases progress slowly and do not require immediate treatment.

1 Dec 2025

Automated production of lung organoids could revolutionize the development of treatments

A team of scientists have developed a simple method for automated manufacturing of lung organoids which could revolutionize the development of treatments for lung disease.

1 Dec 2025

Designing better RNA delivery polymers with computational tools

A research team led by professor Olivia Merkel, Chair of Drug Delivery at LMU and co-spokesperson of the Cluster for Nucleic Acid Therapeutics Munich (CNATM) has developed the first integrated platform that combines molecular dynamics (MD) simulations and machine learning (ML) to identify new polymeric materials for therapeutic RNA delivery.

1 Dec 2025

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

Chronic muscle tension is a common underlying factor in many pain disorders, causing reduced arterial blood flow, tissue hypoxia, and the release of inflammatory mediators.

28 Nov 2025

How the gut microbiome links obesity to colorectal cancer

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and colorectal cancer.

28 Nov 2025

Breakthrough platform reveals the choreography of mammalian transcription

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

27 Nov 2025

Global Virus Network outlines priorities as Marburg virus emerges in Ethiopia

The Global Virus Network (GVN), a coalition of leading human and animal virologists in more than 40 countries dedicated to advancing pandemic preparedness through research, education and training, and global health solutions, today issued a statement on the newly confirmed outbreak of Marburg virus disease (MVD) in southern Ethiopia.

27 Nov 2025

Researchers capture a ribozyme in motion for the first time

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure.

27 Nov 2025

Therapeutics News and Research

Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

Genetic variant linked to higher heart failure risk in children with myocarditis

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

Ripple & Bausch’s licensing agreement: What it means in ocular delivery

TRIMTECH Therapeutics appoints Alison Lawton as Chair of the Board

Research says global HIV efforts need renewed funding and focus

Researchers uncover GFAP’s role in mitochondrial dysfunction

Mapping SV2A drug binding offers a path to better epilepsy treatments

Advances in screening and therapeutics make lung cancer treatable, survivable

New consortium aims to fast-track breakthroughs against follicular lymphoma

Automated production of lung organoids could revolutionize the development of treatments

Designing better RNA delivery polymers with computational tools

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

How the gut microbiome links obesity to colorectal cancer

Breakthrough platform reveals the choreography of mammalian transcription

Global Virus Network outlines priorities as Marburg virus emerges in Ethiopia

Researchers capture a ribozyme in motion for the first time

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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