Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Long sitting hours raise breast cancer odds for inactive obese women

Prolonged daily sitting is linked to a higher prevalence of breast cancer in obese women, but only among those who are physically inactive. Regular physical activity eliminates this association, highlighting the importance of movement for breast cancer prevention in high-risk groups.

15 Jul 2025

Teen obesity and diabetes may weaken lifelong bone strength

Obesity and type 2 diabetes in adolescence can interfere with bone development, potentially increasing the risk of fractures and osteoporosis later in life, according to a study being presented Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

15 Jul 2025

Popular sugar substitute could raise the risk of blood clots and stroke

From low-carb ice cream to keto protein bars to "sugar-free" soda, the decades-old sweetener erythritol is everywhere.

14 Jul 2025

Intermittent energy restriction shows strong benefits for people with obesity and type 2 diabetes

Intermittent energy restriction, time-restricted eating and continuous energy restriction can all improve blood sugar levels and body weight in people with obesity and type 2 diabetes, according to a study being presented Sunday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

13 Jul 2025

New guideline recommends proper preconception care for women with diabetes

A joint guideline released today from the Endocrine Society and the European Society of Endocrinology (ESE) recommends women with diabetes receive proper preconception care and access to emerging diabetes technology and therapeutics to manage their blood sugar before, during and after pregnancy.

13 Jul 2025

Is fruit juice good or bad for diabetes? New research reveals a genetic twist

Japanese adults with a high genetic risk for type 2 diabetes who consumed 100% fruit juice at least once per week had significantly lower odds of developing the disease. The inverse association was not seen in people with low or moderate genetic risk, highlighting gene-diet interactions.

13 Jul 2025

Higher protein intake may help prevent muscle loss in semaglutide users

Women and older adults taking the anti-obesity drug semaglutide may be at higher risk for muscle loss, but higher protein intake may help prevent muscle loss in these patients, according to a small study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Design strategies and therapeutic applications of smart materials in diabetes care

Announcing a new publication for Acta Materia Medica journal. Bioresponsive materials have gained prominence as innovative tools for advancing drug delivery systems, particularly in managing type 1 and type 2 diabetes mellitus.

12 Jul 2025

Weight loss wipes out senescent fat cells but leaves immune scars, study finds

Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

10 Jul 2025

Does pomegranate seed oil really help your heart? New research weighs the evidence

This review explores the potential of punicic acid in pomegranate seed oil as a nutraceutical for cardiovascular health. While preclinical evidence is promising, robust human trials are needed to confirm its benefits.

10 Jul 2025

Lower body temperature found to directly influence glucose metabolism in mice

Some mammals are capable of hibernating during periods of low food availability in an effort to conserve energy and survive.

10 Jul 2025

MIT develops implantable device to automatically release emergency glucagon

For people with Type 1 diabetes, developing hypoglycemia, or low blood sugar, is an ever-present threat. When glucose levels become extremely low, it creates a life-threatening situation for which the standard treatment of care is injecting a hormone called glucagon.

9 Jul 2025

Innovative genome editing approach could be the key to lifelong effective weight management

Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment.

9 Jul 2025

New Scientific Statement outlines future research directions for type 1 diabetes

A new Scientific Statement released today by the Endocrine Society highlights potential research directions related to the pathogenesis of type 1 diabetes (T1D) that should help with the development of new and improved treatment options.

9 Jul 2025

Study finds no metabolic danger from ultra-processed foods

Research shows ultra-processed foods contribute to poor diet quality without a significant association to metabolic syndrome among European children and adults.

9 Jul 2025

New study identifies factors linked to successful weight loss using GLP-1RAs

A study in Diabetes, Obesity and Metabolism has identified certain characteristics that might influence people's weight loss after taking prescription drugs called glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide (sold under the brand names Ozempic and Wegovy).

9 Jul 2025

Many Americans misunderstand the health impact of processed foods

Thirty-nine percent of respondents to an online poll incorrectly said all processed foods are unhealthy, according to new research by the Physicians Committee for Responsible Medicine published today, July 8, 2025, in JAMA Network Open.

9 Jul 2025

More fiber, fewer health risks: evidence for this easy diet fix

This study reveals that adequate dietary fiber intake is crucial for lowering obesity risk and mortality, supporting its role in effective weight management.

9 Jul 2025

Why vitamin B6 could raise the risk of hypoglycemia for people with diabetes

A large-scale Mendelian randomization study found no genetic evidence that vitamins A, C, or D reduce the risk of major diabetic complications. However, higher genetically predicted vitamin B6 levels were strongly associated with increased risk of diabetic hypoglycemia, warranting caution with supplementation.

8 Jul 2025