Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

New and updated clinical practice guidelines released for treatment of pediatric venous thromboembolism

The American Society of Hematology (ASH) and the International Society on Thrombosis and Haemostasis (ISTH) released new and updated clinical practice guidelines for the treatment of pediatric venous thromboembolism (VTE).

27 May 2025

Single antiplatelet therapy after TAVR linked to lower mortality and bleeding

Findings from the Transfusion Requirements in Transcatheter Aortic Valve Implantation (TRITAVI) registry demonstrate that single antiplatelet therapy (SAPT) after transcatheter aortic valve replacement (TAVR) is associated with a significantly lower incidence of six-month mortality and major bleeding risk compared to dual antiplatelet therapy (DAPT).

2 May 2025

CAD/CAM techniques improve outcomes in jaw reconstruction after cancer surgery

For patients undergoing jaw reconstruction after surgery for head and neck cancer, computer-aided design and manufacturing (CAD/CAM) techniques can improve some key clinical outcomes, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

30 Apr 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

New thromboinflammation-on-a-chip model may revolutionize treatment of harmful blood clots

Blood clots are associated with life-threatening conditions such as sepsis, sickle cell disease, heart attack, and stroke.

3 Apr 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Reduced-dose apixaban proves effective in preventing blood clot recurrence in cancer patients

Patients with active cancer who developed a blood clot, or venous thromboembolism (VTE), and were treated with blood-thinning medication for at least six months, followed by an additional 12 months of low-dose apixaban, experienced similar VTE recurrences and less bleeding as similar patients who received a full dose of the oral blood-thinning medication over the same extended period.

29 Mar 2025

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

At three months of follow-up, patients hospitalized for a serious heart attack who were treated with the oral blood thinner rivaroxaban for a blood clot in the left ventricle did as well as similar patients who received standard treatment with warfarin, an older blood-thinning drug.

29 Mar 2025

Understanding how JAK inhibitors may increase blood clot risk

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?

17 Mar 2025

Study shows potential of uric acid as add-on therapy for stroke

In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work as an add-on therapy to standard stroke treatments in humans.

17 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

RCSI study finds immune cell ‘memories’ can increase the risk for blood clots long after inflammation

New research from RCSI University of Medicine and Health Sciences has found that white blood cells which ‘remember’ past inflammation events are quick to overreact, raising the risk of blood clots.

10 Mar 2025

Aspirin may help prevent cancer spread by stimulating the immune system

Scientists have uncovered the mechanism behind how aspirin could reduce the metastasis of some cancers by stimulating the immune system.

5 Mar 2025

Study reveals best treatment strategy for high-risk pulmonary embolism

A current study involving the University Hospital Bonn (UKB) has investigated which treatment strategy offers the best chances of survival in high-risk acute pulmonary embolism.

4 Mar 2025

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

Scientists use Zwitterions to prevent blood clotting in medical devices

Zwitterions sound likes a distant cousin of Twitter (X), but in fact they are a common macromolecule found in human cells. Scientists at the University of Sydney are also now using Zwitterions to create materials that could stop blood clots from forming in medical devices and implants.

19 Feb 2025

Risk of bleeding with blood thinners reduces over time

Blood thinners prescribed after blood clots in leg or lung initially increase the risk of bleeding, especially in women and elderly.

14 Feb 2025

Lung signals trigger blood clot formation in cancer patients

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.

11 Feb 2025

Tenecteplase injection after clot removal improves stroke recovery

Removing a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in stroke survivors being more likely to have better function 90 days after their stroke than those receiving standard clot removal, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

8 Feb 2025

Blood Clot News and Research

Further Reading

New and updated clinical practice guidelines released for treatment of pediatric venous thromboembolism

Single antiplatelet therapy after TAVR linked to lower mortality and bleeding

CAD/CAM techniques improve outcomes in jaw reconstruction after cancer surgery

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

New thromboinflammation-on-a-chip model may revolutionize treatment of harmful blood clots

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

Reduced-dose apixaban proves effective in preventing blood clot recurrence in cancer patients

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

Understanding how JAK inhibitors may increase blood clot risk

Study shows potential of uric acid as add-on therapy for stroke

New stem cell-based vascular grafts could revolutionize cardiac surgery

RCSI study finds immune cell ‘memories’ can increase the risk for blood clots long after inflammation

Aspirin may help prevent cancer spread by stimulating the immune system

Study reveals best treatment strategy for high-risk pulmonary embolism

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Scientists use Zwitterions to prevent blood clotting in medical devices

Risk of bleeding with blood thinners reduces over time

Lung signals trigger blood clot formation in cancer patients

Tenecteplase injection after clot removal improves stroke recovery

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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