immunity News and Research

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Engineered nanoparticles sensitize gliomas to radiotherapy

Gliomas are a major cause of cancer-related deaths in younger adults.

24 Sep 2026

Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases

Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated signal transduction.

23 Sep 2026

A hidden measles signal may reveal how large the next outbreak could be

Researchers used historical measles surveillance and demographic data from pre-vaccination England and Wales to reconstruct how the susceptible population changed between epidemics. Their model linked susceptibility at the start of an epidemic year with the magnitude of the following outbreak, pointing to a potential route for one-year-ahead forecasting that requires further development for modern surveillance settings.

22 Sep 2026

Sensory neurons remember past allergens to trigger future allergic reactions

Mass General Brigham researchers found that sensory neurons retain a 'memory' of allergens that may help explain why allergies develop over time.

22 Sep 2026

World Cup travel and low vaccination fuel Latin American measles outbreaks

Countries in Latin America are being urged to strengthen vaccination and surveillance to fight measles as the region records the highest number of cases in more than two decades, disease experts say.

21 Sep 2026

Measles outbreaks may reveal more than gaps in vaccination

A commentary in Human Vaccines & Immunotherapeutics argues that measles outbreaks can serve as a sensitive indicator of weaknesses in vaccination coverage, surveillance, health equity, community trust, and broader immunization systems. The authors contend that pursuing measles eradication could also strengthen routine immunization, laboratory capacity, outbreak preparedness, and health-system resilience.

21 Sep 2026

A 194-country analysis reveals gaps in how late childhood vaccinations are tracked

A global analysis of WHO/UNICEF data from 194 countries found wide variation in countries’ ability to record delayed childhood vaccinations, with 64% of reporting countries saying they could capture late doses in 2022. Following birth cohorts over time and adding delayed MCV1 doses raised median coverage estimates by 3.6 to 5.1 percentage points across available cohort years, though incomplete and inconsistent reporting limited confidence in some estimates.

21 Sep 2026

Global Virus Network monitors spreading avian influenza in Australian mammals

The Global Virus Network (GVN) is closely monitoring detections of highly pathogenic avian influenza A (H5N1), commonly known as bird flu, in several mammal species in Australia as the virus continues to spread among birds and mammals worldwide.

18 Sep 2026

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

17 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Innate immune system variations determine vaccine side effects

Redness and pain at the injection site, fever, fatigue or headaches: vaccines can cause side effects, but their frequency and severity vary considerably from person to person.

17 Sep 2026

Salk scientists demonstrate B cells directly enhance killer T cell function

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026

Lupus-linked genetic variants may boost antiviral immunity

Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?

11 Sep 2026

Study shows mRNA vaccines trigger more diverse flu antibody responses

Influenza remains a major global health challenge as continual antigenic drift can limit the breadth and durability of vaccine-induced antibody responses, requiring frequent vaccine updates.

11 Sep 2026

Avoiding antibody-dependent enhancement enables dengue prevention and treatment

Dengue virus is one of the most widespread vector-borne viral pathogens in the world. Nearly 400 million dengue virus infections occur each year, resulting in approximately 20,000 deaths.

10 Sep 2026

Refined starch activates immune pathways after low-carb weight loss

After substantial weight loss on a very-low-carbohydrate diet, participants who switched to a diet rich in refined starch showed greater activation of circulating immune and metabolic pathways than those who continued the low-carbohydrate diet or consumed a high-carbohydrate diet rich in added sugar. Mouse experiments suggested that activation of the complement immune pathway may help explain the inflammatory response associated with starch intake.

10 Sep 2026

Autistic people face a fourteen-year deficit in life expectancy

People with autism spectrum disorder (ASD) in the United States face a 14-year deficit in life expectancy, according to a new study by researchers at Columbia University Mailman School of Public Health and University of Colorado Anschutz.

10 Sep 2026

C. diff uses dual-threat sensing system to survive gut stress

The pathogen Clostridioides difficile (C. diff) - a leading cause of hospital-acquired infections - must contend with a variety of threats inside the harsh environment of the gut to survive and grow.

9 Sep 2026

Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

In mice, intestinal infections reshaped dural CD4+ T-cell populations and seeded the brain’s outer meningeal border with antigen-specific memory cells that persisted for months and mounted rapid recall responses to bloodborne antigens. Oral priming was associated with reduced Salmonella spread to the brain and modest cross-protection in an engineered shared-antigen Candida model, although the researchers could not definitively prove that dural CD4+ T cells alone caused the protection.

9 Sep 2026

New AI method tracks immune responses without known antibody databases

A research team comprising Associate Professor FUNAKOSHI Yohei, Associate Professor YAKUSHIJIN Kimikazu, Professor MINAMI Hironobu, and Associate Professor OHJI Goh of Kobe University, together with graduate student MASUDA Genki, then-graduate student IIZUMI Shunsuke, Associate Professor OHUE Masahito, and colleagues at the Institute of Science Tokyo, has developed a new analysis method, LM-QASAS.

9 Sep 2026