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Single-dose dengue vaccine will benefit populations in hard-to-reach regions

A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon, say disease specialists.

4 Dec 2025

New analysis reveals fundamental flaws in widely used measures of biological aging

A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and conceptualizes biological aging.

3 Dec 2025

Settling the creatine safety debate

Research confirms creatine's safety, highlighting misinformation and low-quality supplements as primary concerns over cancer and kidney health risks.

3 Dec 2025

Insect flour could boost gut health and cut environmental impact

Chitin-rich insect flours show promise as functional foods, boosting beneficial gut bacteria while addressing allergenicity and consumer trust issues.

3 Dec 2025

Tai chi proves as effective as CBT for long-term insomnia relief

Researchers compare the efficacy of Tai chi with cognitive behavioral therapy for the treatment of chronic insomnia.

3 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

Automated EHR system triages cancer symptoms, improves care team efficiency

For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.

3 Dec 2025

Common water pill may be a useful add‑on to the standard HIV treatment

An FDA‑approved medication called spironolactone, often prescribed as a diuretic, or water pill, for heart and blood pressure conditions, may be a useful add‑on to the standard HIV treatment, according to new research from the Valente lab at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology.

2 Dec 2025

AI-assisted liquid biopsies show promise for early cancer detection

The prospect of diagnosing cancer through painless methods—such as a simple AI-assisted blood or urine test that detects tiny particles known as exosomes—is becoming increasingly realistic.

2 Dec 2025

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

WHO releases first guideline on the use of GLP-1 therapies for treating obesity

To address the growing global health challenge of obesity, which affects more than 1 billion people, the World Health Organization (WHO) has released its first guideline on the use of Glucagon-Like Peptide-1 (GLP-1) therapies for treating obesity as a chronic, relapsing disease.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Researchers receive NPB grant to develop online food allergy support tool

A team led by Aston University's Professor Rebecca Knibb in the School of Psychology has been awarded a grant by the US National Peanut Board (NPB) to develop an online food allergy support tool.

1 Dec 2025

Mapping SV2A drug binding offers a path to better epilepsy treatments

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

1 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Why calling your Instagram use an addiction can make the problem worse

The addiction label for Instagram use is often misleading, reducing users' control and increasing self-blame, despite rare clinical addiction symptoms.

1 Dec 2025

UTHealth Houston researchers receive NIH grant for fetoscopic spina bifida repair study

A five-year, $2.8 million grant was awarded to researchers at UTHealth Houston by the National Institutes of Health to evaluate the long-term effects on patients enrolled in the "Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair" trial.

1 Dec 2025

New AI tools offer hope for global TB elimination

Researchers have unveiled new AI tools, from smartphone cough analysis to child-friendly screening systems, which could transform how tuberculosis is detected, monitored and prevented.

1 Dec 2025

Designing better RNA delivery polymers with computational tools

A research team led by professor Olivia Merkel, Chair of Drug Delivery at LMU and co-spokesperson of the Cluster for Nucleic Acid Therapeutics Munich (CNATM) has developed the first integrated platform that combines molecular dynamics (MD) simulations and machine learning (ML) to identify new polymeric materials for therapeutic RNA delivery.

1 Dec 2025

Drug combination can bypass cellular defenses in neuroblastoma

A discovery from Australian researchers could lead to better treatment for children with neuroblastoma, a cancer that currently claims 9 out of 10 young patients who experience recurrence.

29 Nov 2025