Gastrointestinal Tract News and Research

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Flavonols found in foods can block drug resistance protein and boost medication absorption

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

6 Aug 2025

New insights reveal how Candida albicans settle and persist in the gut

About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain.

30 Jul 2025

Probiotic bacteria found to reshape cell behavior in vitro

This study reveals how probiotic bacteria directly influence brain cell function, highlighting gut-brain communication and potential therapeutic applications.

23 Jul 2025

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC.

12 Jul 2025

Therapeutic potential of houttuynia cordata polysaccharide in H1N1 and MRSA-induced acute pneumonia

This new article publication from Acta Pharmaceutica Sinica B, discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.

12 Jul 2025

Advancing transdermal insulin delivery through innovative formulation strategies

Announcing a new publication for Acta Materia Medica journal. The prevalence of diabetes is increasing and expected to become a major global health burden.

27 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025

Scientists warn of rising threat as poultry disease shows signs of jumping to humans

Avian Intestinal Spirochaetosis (AIS) is a chronic, underreported poultry disease caused by Brachyspira spp., with rising concern over its zoonotic risk to humans. This review highlights key challenges in diagnosis, antibiotic resistance, transmission, and the urgent need for improved surveillance and new prevention strategies.

23 Jun 2025

Understanding the interconnected roles of microbial, metabolic, and immune biomarkers in IBD

Inflammatory Bowel Disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal tract with a rising global burden.

19 Jun 2025

Popular painkiller use linked to gut microbiome shifts

Upper gastrointestinal involvement is common in Egyptian patients with ulcerative colitis

This study investigates upper gastrointestinal tract (UGIT) involvement in patients with ulcerative colitis (UC), a condition traditionally considered limited to the colon.

30 May 2025

Understanding cow’s milk allergy in breastfed infants

Cow’s milk allergy (CMA) affects up to 2.2% of infants, with a complex interplay of immunological mechanisms, allergen transfer via breast milk, and variable responses to maternal elimination diets. Current evidence challenges the routine use of maternal dietary restrictions, highlighting the need for precise diagnosis and further research.

27 May 2025

Study reveals link between gut health and post-COVID syndrome fatigue

In a recent study, a research team from the Medical University of Vienna has gained new insights into post-COVID syndrome (PCS) and the relevance of a healthy gastrointestinal tract.

21 May 2025

This news might ruin your appetite — and summer

It's a marvel of food technology: ice cream that resists melting.

20 May 2025

Breakthrough microimager offers new possibilities for internal imaging

Researchers have developed an extremely thin, flexible imager that could be useful for noninvasively acquiring images from inside the body. The new technology could one day enable early and precise disease detection, providing critical insights to guide timely and effective treatment.

19 May 2025

Study reveals colonic inflammation as the trigger for beta cell growth in obesity

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway that leads to increased insulin production.

9 May 2025

Understanding the particle drifting effect with Dr. Na Li

Join Dr. Na Li as she explores the mysteries of the particle drifting effect and its practical applications in real-world scenarios.

From Pion Inc 5 May 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.