Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

Study suggests a complex metabolic basis between alcohol consumption and CVD

A new study identified 60 alcohol-associated circulating metabolites, which appear to produce counteractive effects on the risk of heart disease.

27 Nov 2023

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Research in 'Molecular Psychiatry' explores the role of long-chain polyunsaturated fatty acids (LC-PUFAs) in major depressive disorder (MDD) and suicide risk, showing mixed results in clinical trials for depression treatment. The study underscores the need for further investigation into LC-PUFAs' neurobiology to advance personalized medicine for mood disorders and suicide prevention.

26 Nov 2023

Statins may reduce breast cancer mortality rates

The relationship between serological cholesterol levels, statin usage, and breast cancer (BC) mortality.

21 Nov 2023

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

A review in Nature Reviews Neurology discusses the pathophysiological processes in vascular cognitive impairment and dementia (VCID), emphasizing the need for specific biomarkers to differentiate VCID from Alzheimer's disease and to improve diagnosis and treatment strategies, moving beyond reliance on neuroimaging and patient histories.

15 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Broccoli sprouts diet protects mice from Crohn's disease, study shows

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice.

9 Nov 2023

Avocado a day may keep diabetes at bay, suggests nutritional biomarker study

New research in The Journal of Nutrition links avocado consumption with lower diabetes risk, revealing specific metabolomic biomarkers that indicate potential for reduced fasting glucose and insulin levels.

5 Nov 2023

Advances in grain research illuminate potential for precision nutrition in clinical settings

Grains are a primary source of energy (calories) in the diet.

1 Nov 2023

Research reveals both protective and harmful gut microbiota associated with sleep apnea risk

The causal relationship between gut microbiota, associated metabolites, and obstructive sleep apnea (OSA).

30 Oct 2023

Can metabolic biomarkers help distinguish between depressive episodes of bipolar disorder and major depressive disorder?

Researchers identify metabolomic biomarkers from dried blood spots that can distinguish between depressive episodes in major depressive disorder and bipolar disorder. The study enhances diagnostic accuracy, particularly when traditional psychiatric assessments are inconclusive.

26 Oct 2023

Exploring the link between red meat intake and inflammation

Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest.

26 Oct 2023

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

A recent study in "Microorganisms" delves into the relationship between the microbiome and biliary tract cancer, revealing distinct microbial compositions in patients compared to healthy individuals. This research highlights potential diagnostic biomarkers and suggests that altering gut microbial composition might enhance responses to cancer immunotherapy.

24 Oct 2023

New insights into why obesity puts individuals at risk for severe influenza

The mechanisms underpinning severe cases of influenza among the obese population.

23 Oct 2023

Low serotonin levels observed in long COVID and other viral infections

Researchers identify a pathophysiological mechanism linking serotonin reduction to the multifaceted etiology of post-acute sequelae of COVID-19.

20 Oct 2023

How do different organ microbiomes influence neuropsychiatric disorders?

Scientists review existing literature to understand how the microbiome influences neuropsychiatric disorders.

19 Oct 2023

Supercharge your kale juice: Fermentation ramps up antioxidant and anti-inflammatory powers

Fermenting kale juice with Limosilactobacillus strains boosts its antioxidant and anti-inflammatory properties, according to a new study in the journal Antioxidants. The research suggests that this bacteria-enhanced juice could offer enhanced health benefits, including elevated levels of beneficial phytonutrients like quercetin and kaempferol.

15 Oct 2023

Diet drinks may affect blood sugar levels, insulin resistance and gut microbiome

‘Full fat’ sugary drinks such as colas increase the risk of obesity and are generally off-limits for diabetics.

14 Oct 2023

Common herbicide exposure linked to worse brain function in adolescents

Herbicides are the most used class of pesticides worldwide, with uses in agriculture, homes and industry. Exposures to two of the most popular herbicides were associated with worse brain function among adolescents, according to a study led by researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego.

12 Oct 2023

Study reveals a microbial metabolite's role in inducing Parkinson's-like symptoms

Researchers from the University of Vienna, University of Konstanz, and Albert Einstein College of Medicine uncover a potential environmental trigger for Parkinson's disease.

11 Oct 2023