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Curcumin shows promise in preventing and treating oral submucosal fibrosis

Researchers explore the mechanisms, therapeutic potential, and clinical applications of curcumin in preventing and treating oral submucosal fibrosis.

30 Oct 2024

Toddler’s backyard snakebite bills totaled more than a quarter million dollars

This spring, a few days after his 2nd birthday, Brigland Pfeffer was playing with his siblings in their San Diego backyard.

30 Oct 2024

For people with opioid addiction, Medicaid ‘unwinding’ raises the stakes

It was hard enough for Stephanie to get methadone treatment when she moved to Florida from Indiana last year. The nearest clinic was almost an hour's drive away and she couldn't drive herself. But at least she didn't have to worry about the cost of care.

30 Oct 2024

Drug repurposing offers hope for SYNGAP1 patients

The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor in the Department of Human Genetics at the University of Utah. These grants are crucial steps in advancing therapeutic development for SYNGAP1-Related Disorders (SRD).

30 Oct 2024

New device enables real-time monitoring of stem cell growth

Unlike most cells in the human body, stem cells have the unique ability to divide indefinitely. This unique property makes them especially appealing to scientists exploring ways to extend human lifespans or develop new methods for repairing damaged tissues.

30 Oct 2024

Short bursts of exercise can lower dementia risk

Just one or two sessions of physical activity at the weekend - a pattern of exercise dubbed 'weekend warrior'---may be just as likely to lower the risk of cognitive decline, which can often precede dementia, as more frequent sessions, concludes research published online in the British Journal of Sports Medicine.

30 Oct 2024

Exercise linked to lower mortality risk in dementia patients

Physical activity of any intensity after a diagnosis of dementia is associated with around a 30% lower risk of death, finds research published online in the British Journal of Sports Medicine.

30 Oct 2024

Study challenges early intervention for asymptomatic aortic stenosis

The EVOLVED trial found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis (AS) and mid-wall myocardial fibrosis on magnetic resonance imaging did not reduce the incidence of the composite primary endpoint of all-cause death or unplanned aortic stenosis hospitalization compared with guideline-directed conservative management.

30 Oct 2024

Machine learning reveals secrets of aging in flies and humans

Discoveries that impact lifespan and healthspan in fruit flies are usually tested in mice before being considered potentially relevant in humans, a process that is expensive and time intensive. A pioneering approach taken at the Buck Institute leapfrogs over that standard methodology.

30 Oct 2024

Researchers uncover link between smell and inflammation

Researchers from the Charlie Dunlop School of Biological Sciences, in collaboration with The Oxford Research Centre in the Humanities, reveal a powerful link between olfactory loss and inflammation in a staggering 139 medical conditions. This research – led by professor emeritus Michael Leon, and researchers Cynthia Woo and Emily Troscianko – emphasizes a little-known but potentially life-altering connection: the role our sense of smell plays in maintaining our physical and mental health.

30 Oct 2024

New funding boosts efforts to revitalize flint communities

The Prevention Research Center of Michigan has spent decades researching ways to create safer, more inviting, and accessible neighborhood spaces to improve physical and mental health. Now, $5 million in renewed funding from the U.S. Centers for Disease Control and Prevention will enable the center to continue its community-based participatory research projects through at least 2029.

30 Oct 2024

Researchers identify genetic markers for cardiovascular disease

A team of researchers from Girona Biomedical Research Institute Dr. Josep Trueta (IDIBGI), Bellvitge Biomedical Research Institute (IDIBELL), IRB Barcelona, Institut Català d'Oncologia (ICO), Germans Trias i Pujol Research Institute (IGTP) has worked together to identify possible genes associated with certain metabolites - molecules involved in the body's biochemical processes - and cardiovascular risk.

30 Oct 2024

Scientists develop color-coded X-rays to detect early disease

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white diagnostic images of X-rays and traditional CT scans into technicolor. The researchers developed novel contrast agents that target two proteins implicated in osteoarthritis, a degenerative joint disease commonly characterized as wear-and-tear arthritis.

30 Oct 2024

New test promises to end malaria

Almost half of the world's population is at risk of malaria infection, with children and pregnant women at the highest risk of getting sick and dying from the disease. Current methods to detect this potentially deadly infection rely on obtaining an invasive blood sample, and each test has significant limitations that restrict its utility.

29 Oct 2024

Non-invasive ultrasound therapy targets brain disorders, offers hope

Ultrasound, once used almost exclusively to take images of the body, is quickly developing into a targeted therapy that can have a potentially life-changing impact on our brains, according to the authors of a new article.

29 Oct 2024

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

29 Oct 2024

Radioprotective effects of Licochalcone B against radiation-induced cell damage

Radiation injury poses a serious threat to human health, causing complex and multifaceted damage to cells and tissues. Such injury can be caused by various factors, including nuclear accidents, medical radiation therapy, and space travel.

29 Oct 2024

Ratiometric fluorescent probes for measuring active albumin in liver disease patients

Albumin is a major prognostic factor for patients with advanced liver disease, dependent on its concentration and biological activity.

29 Oct 2024

Unraveling the mechanism of Shufeng Jiedu Capsules in influenza treatment

Shufeng Jiedu Capsules (SFJD), a traditional Chinese medicine preparation, are widely used in the clinical treatment of influenza, yet their mechanism of action remains unclear.

29 Oct 2024

Researchers develop new approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.

29 Oct 2024