Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Short-term, calorie-restrictive diet improves Crohn’s disease symptoms

A Stanford Medicine-led study finds a short-term, calorie-restrictive diet significantly improved symptoms.

13 Jan 2026

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

Sinai Health researchers have shown a blood test that can predict Crohn's disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention.

12 Jan 2026

$AGA's new update urges caution before surgical treatment of refractory constipation$

AGA's new update urges caution before surgical treatment of refractory constipation

A new update from the American Gastroenterological Association (AGA) is calling for greater caution before surgery is considered for patients with refractory constipation, a severe, chronic form of constipation that does not respond to standard treatments.

7 Jan 2026

Children’s Hospital Colorado completes its first heart and liver dual transplant

Children's Hospital Colorado (Children's Colorado) successfully performed the hospital's first-ever heart and liver dual organ transplant, with support from dozens of team members across 25 different multidisciplinary care teams.

19 Dec 2025

$New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer$

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs.

5 Dec 2025

Asian IBD patients show lower PSC prevalence and better clinical outcomes

Primary sclerosing cholangitis (PSC) is a chronic, progressive inflammatory disease characterized by fibrosis and bile duct stricturing, which ultimately leads to cirrhosis and liver failure. PSC is strongly associated with both types of inflammatory bowel disease (IBD), namely, ulcerative colitis and Crohn's disease.

2 Dec 2025

Assessment of pre-procedure versus spray-as-you-go airway anesthesia protocols in bronchoscopy

Fiberoptic bronchoscopy involves various topical airway anesthesia protocols, which can impact patient comfort, procedural ease, and overall outcomes.

25 Nov 2025

Researchers uncover a new way to understand how children fare after liver transplantation

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a new way to understand how children fare after liver transplantation: by focusing not on medical test results, but on how differently parents and children perceive the child's well-being.

24 Nov 2025

New prognostic tool can predict transplant needs in drug-induced liver injury patients

A newly developed tool, called the DILI-Inpt prognostic score, can predict patients with drug-induced liver injury who are unlikely to survive without a liver transplant.

19 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to advance precision diagnostics and significantly improve chronic disease outcomes for at-risk patients, today announced a collaboration with a leading global pharmaceutical company recognized for its expertise in precision medicine and biomarker-guided drug development.

From Mursla Bio 13 Nov 2025

Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease

Chronic liver disease (CLD) and its advanced stage, cirrhosis, represent a significant global health burden, with portal hypertension (PH) being a primary driver of disease progression and decompensation.

12 Nov 2025

Study clarifies how biliary atresia overlaps with multiple congenital syndromes

Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or transplantation in early infancy.

12 Nov 2025

Assessing health system preparedness for MASLD in the Middle East and North Africa

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents an escalating healthcare burden across the Middle East and North Africa (MENA) region; however, system-level preparedness remains largely undefined.

11 Nov 2025

Genetic and cellular mechanisms underlying steatotic liver disease

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), has emerged as the dominant cause of chronic liver disease worldwide, displacing viral hepatitis as the primary aetiology.

10 Nov 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Liver transplants from MAiD donors show outcomes comparable to standard donations

Organ donation following medical assistance in dying (MAiD), also known as euthanasia, is a relatively new practice both in North America and worldwide.

27 Oct 2025

Ingestible capsule developed for the diagnosis of acute mesenteric ischemia

Researchers led by investigators at Mass General Brigham and Massachusetts Institute of Technology have validated an ingestible capsule in preclinical models for the diagnosis of acute mesenteric ischemia, a condition caused by blocked or reduced blood flow to the intestines.

22 Oct 2025

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

22 Oct 2025

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University of Technology, University of Queensland, and Nanjing Stomatological Hospital has introduced groundbreaking three-dimensional (3D) dynamic cell co-culture models to simulate metabolic dysfunction-associated steatotic liver disease (MASLD) progression stages.

22 Oct 2025

Hepatology News and Research

Further Reading

Short-term, calorie-restrictive diet improves Crohn’s disease symptoms

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

AGA's new update urges caution before surgical treatment of refractory constipation

Children’s Hospital Colorado completes its first heart and liver dual transplant

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

Asian IBD patients show lower PSC prevalence and better clinical outcomes

Assessment of pre-procedure versus spray-as-you-go airway anesthesia protocols in bronchoscopy

Researchers uncover a new way to understand how children fare after liver transplantation

New prognostic tool can predict transplant needs in drug-induced liver injury patients

Understanding leptin's dual function in MAFLD pathogenesis

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease

Study clarifies how biliary atresia overlaps with multiple congenital syndromes

Assessing health system preparedness for MASLD in the Middle East and North Africa

Genetic and cellular mechanisms underlying steatotic liver disease

Lab-grown organoid offers a platform to study how liver scarring develops

Liver transplants from MAiD donors show outcomes comparable to standard donations

Ingestible capsule developed for the diagnosis of acute mesenteric ischemia

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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