Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Study connects vascular health to early Alzheimer’s brain changes

Subtle changes in how blood flows through the brain and how brain tissue uses oxygen may be closely linked to Alzheimer's disease risk, according to new research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC.

23 Feb 2026

New maps of mouse brains reveal patterns of myelin formation

Johns Hopkins scientists say they have used 3D imaging, special microscopes and artificial intelligence (AI) programs to construct new maps of mouse brains showing a precise location of more than 10 million cells called oligodendrocytes.

22 Feb 2026

Low-fiber diets quickly impair emotional memory in aging brains

Past studies in animals have shown that a highly processed diet is linked to memory problems and inflammation in the aged brain – and the effect can happen fast, after just three days of poor eating.

19 Feb 2026

New technology maps protein production across individual brain cells

The brain's ability to carry out everything from forming memories to coordinating movement depends on its cells producing the right proteins at the right time.

18 Feb 2026

Brain circuit links past experiences to appetite control

Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified brain cells that translate contextual information into appetite control.

12 Feb 2026

Early cognitive stimulation preserves memory in Alzheimer’s

A team from the Institute of Neurosciences of the University of Barcelona (UBneuro) has discovered that early and sustained cognitive stimulation can help preserve brain connectivity and memory in Alzheimer's disease, even in advanced stages of the pathology.

12 Feb 2026

Defective ASTN1 gene linked to developmental delay and neurological disorders

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development.

10 Feb 2026

'Partial reprogramming' of engram neurons restores memory performance in mice

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible.

10 Feb 2026

Brain immune cells regulate new neuron formation in adults

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

9 Feb 2026

Needle-thin brain implant enables recording and targeted drug delivery

A new type of brain implant may have implications for both brain research and future treatments of neurological diseases such as epilepsy.

6 Feb 2026

Estrogen levels in the brain may play a role in women’s risk of stress-related memory problems

Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting memory scars.

3 Feb 2026

MRI scans reveal human brain growth from pregnancy through birth

Analyzing brain growth across pregnancy and early life, this study offers new insights into sex-specific development and its implications for neurodevelopment.

3 Feb 2026

Hippocampus reorganizes memories to anticipate future outcomes, study finds

A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes memories to anticipate future outcomes.

30 Jan 2026

Study uncovers how the brain's 'memory replay' process is impaired in Alzheimer's disease

Memory dysfunction in Alzheimer's disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice by University College London (UCL) scientists.

29 Jan 2026

KAIST proposes novel strategy for multifactorial Alzheimer's treatment

Conventional treatments of Alzheimer's disease, one of the most common forms of dementia, have been largely focused on targeting individual pathological features.

27 Jan 2026

Menopause associated with reduced brain volume and increased anxiety symptoms

Menopause is linked to reductions in grey matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep, according to new research from the University of Cambridge.

27 Jan 2026

Ageing slows brain protein clearance and shifts synaptic waste to microglia

Ageing slows neuronal protein degradation in mice, leading to widespread accumulation and aggregation of long-lived proteins, particularly at synapses. As neuronal clearance declines, microglia selectively accumulate synaptic proteins, suggesting a compensatory but potentially strained proteostasis pathway in the ageing brain.

22 Jan 2026

The neuroscience of motivation-driven memory retention

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and Duke University have proposed a neuroscience framework explaining how different types of motivation fundamentally reshape what and how the brain remembers.

21 Jan 2026

Suppressing brain immune cells enhances memory recall in young mice

Babies of every species from mouse to human rapidly forget things that happen to them-an effect called infantile amnesia.

20 Jan 2026

Blocking microglia can prevent infantile amnesia

Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting ("infantile amnesia") and improves memory in mice, suggesting that microglia may actively manage memory formation and dictate what, and when, we forget.

20 Jan 2026