Aging News and Research

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Increasing numbers of bariatric surgery patients turn to GLP-1 drugs

Bariatric surgery is usually effective on its own for weight loss, but an increasing proportion of patients who undergo bariatric surgery start taking one of the new glucagon-like 1 peptide receptor agonist (GLP-1) weight-loss drugs in the years after their surgery, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

27 Aug 2025

AUF1 protein shown to suppress cellular senescence and altered metabolism

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 24, 2025, titled "RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs."

27 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

Faster biological aging associated with lower cognitive performance in later life

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 21, 2025, titled "Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study."

26 Aug 2025

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

In a groundbreaking study, research scientists from the Indiana University School of Medicine and Regenstrief Institute found that individuals with a parent who died from liver disease face more than double the risk of developing alcohol-associated hepatitis, one of the deadliest forms of alcohol-related liver disease, compared with similar heavy drinkers without that family history.

26 Aug 2025

Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

In a revealing Genomic Press Interview published today in Brain Medicine, Professor Alexei Verkhratsky dismantles decades of neuroscience orthodoxy with discoveries that position neuroglia as active architects of brain function rather than passive cellular bystanders.

26 Aug 2025

Having a sense of purpose linked to lower dementia risk

Research into Blue Zones - regions of the world where people tend to live longer - shows that having a sense of purpose in life may help people live longer.

25 Aug 2025

Can diet alone slow brain aging? Scientists say evidence is still too weak

Researchers reviewing evidence in the Annual Review of Nutrition find that healthy dietary patterns may support brain aging, but caution that scientific enthusiasm currently outpaces solid proof. Multidomain strategies combining diet with exercise, cognitive training, and vascular health show greater promise.

25 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis - a serious complication of diabetes and a leading cause of kidney failure - according to a new study from researchers at the University of Illinois Urbana-Champaign and Mie University in Japan.

25 Aug 2025

Positive emotion bias in aging may signal cognitive decline

As people age, they display a bias in recognizing emotions as positive-to the point of improperly labeling neutral or negative emotions as positive.

25 Aug 2025

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

In rapidly aging societies like Japan, the simple act of swallowing meals can be challenging for many. This condition, known as dysphagia, affects millions of people worldwide and can significantly deteriorate a person's quality of life.

22 Aug 2025

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

22 Aug 2025

Excessive amounts of visceral fat tied to faster heart aging

Excessive amounts of visceral fat - the hidden fat surrounding organs - is linked with faster aging of the heart, a new study has found.

22 Aug 2025

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study finds.

22 Aug 2025

Research examines how cancer may invalidate forensic age-estimation tools

Patients with solid tumors, including breast and lung cancers, showed only slightly less accurate results. In contrast, individuals with blood cancers, particularly chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), sometimes had large errors, with ages overestimated by as much as 50 years.

22 Aug 2025

Hemoglobin emerges as a natural antioxidant defense in the brain

Did you know the same protein that gives blood its red color and carries oxygen throughout the body is also present inside brain cells? Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked - and potentially game-changing - antioxidant role in the brain.

22 Aug 2025

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025

Less education associated with faster aging and health inequality

A new study by USC Leonard Davis School of Gerontology researchers shows that Americans with less education are aging faster than their peers with more schooling, and the gap has grown over the last 30 years.

21 Aug 2025

Computational approach provides insight into neural progenitor cells and their role in brain disorders

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

21 Aug 2025

Aging News and Research

Increasing numbers of bariatric surgery patients turn to GLP-1 drugs

AUF1 protein shown to suppress cellular senescence and altered metabolism

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

Faster biological aging associated with lower cognitive performance in later life

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

Having a sense of purpose linked to lower dementia risk

Can diet alone slow brain aging? Scientists say evidence is still too weak

Fat location, not BMI, drives heart ageing risk in men and women

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

Positive emotion bias in aging may signal cognitive decline

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Excessive amounts of visceral fat tied to faster heart aging

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Research examines how cancer may invalidate forensic age-estimation tools

Hemoglobin emerges as a natural antioxidant defense in the brain

Research shows how lysosomes respond to stress

Less education associated with faster aging and health inequality

Computational approach provides insight into neural progenitor cells and their role in brain disorders

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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