Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Evaluating allogeneic transplant for TP53 mutated acute myeloid leukemia

A new editorial was published in Oncotarget's Volume 15 on October 1, 2024, entitled, "Transplant or no transplant for TP53 mutated AML."

12 Oct 2024

New computational pipeline revolutionizes personalized cancer vaccine design

Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses artificial intelligence algorithms to use its output to design personalized cancer vaccines for patients.

12 Oct 2024

Harnessing neural networks to forecast treatment outcomes in small cell lung cancer

As immunotherapy makes breakthrough progress in the treatment of small cell lung cancer (SCLC), predicting treatment outcomes has become a focal point in clinical practice. Immunotherapy combined with chemotherapy has been approved as first-line therapy for small cell lung cancer due to its survival benefit in randomized controlled trials.

12 Oct 2024

Innovative approaches to lymphatic pain relief in breast cancer patients

Among the 7.8 million women with breast cancer worldwide, at least 33% to 44% are affected by lymphatic pain. Breast cancer survivors usually suffer lymphatic pain in the ipsilateral body or upper limb, and pharmacological approaches are not effective for lymphatic pain.

12 Oct 2024

Breakthrough in mirror molecule synthesis opens doors for drug discovery

A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of "mirror molecules" found in nature and assess them for potential use against cancer, infection, depression, inflammation and a host of other conditions.

10 Oct 2024

Study reveals financial hardships in cancer fundraising campaigns

In a new, large comprehensive analysis led by the American Cancer Society (ACS), researchers, using a form of Artificial Intelligence (AI), found that more than one-third of fundraising stories on the GoFundMe crowdfunding platform in the United States explicitly shared experiences of medical financial hardships and health-related social needs (HRSNs).

10 Oct 2024

Older men’s connections often wither when they’re on their own

At age 66, South Carolina physician Paul Rousseau decided to retire after tending for decades to the suffering of people who were seriously ill or dying. It was a difficult and emotionally fraught transition.

10 Oct 2024

CRISPR-based rapid molecular diagnostic developed for two forms of leukemia

Researchers at Dana-Farber Cancer Institute have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions.

9 Oct 2024

Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Dual immunotherapy plus chemotherapy shows promise for specific lung cancer patients

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

9 Oct 2024

New review explores Zika virus as a potential treatment for brain cancer

A new review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review."

9 Oct 2024

Gene therapy offers hope for children with cerebral adrenoleukodystrophy

Cerebral adrenoleukodystrophy (CALD) is a rare progressive, genetic brain disease that primarily presents in young boys, causing loss of neurological function and ultimately leading to early death.

9 Oct 2024

Major studies reveal improved treatment for children with Group 3 medulloblastoma

Vital research findings pointing to improved treatment for children with Group 3 medulloblastoma brain tumors have been revealed in two major studies published in the journal Neuro-Oncology.

9 Oct 2024

NCCN and LACOG collaborate to enhance cancer care in South America

The National Comprehensive Cancer Network® (NCCN®) - an alliance of leading cancer centers in the United States - announces a renewed collaboration with the Latin American Cooperative Oncology Group (LACOG) to improve cancer outcomes in South America.

9 Oct 2024

Concerns rise over increased industry sponsorship in cancer clinical trials

A growing reliance on industry-sponsored cancer clinical trials in the United States is a reason for concern, say researchers from the UNC Lineberger Comprehensive Cancer Center.

8 Oct 2024

Mosaic Therapeutics appoints Dr Barry Davies as CSO

Dr. Barry Davies joins Mosaic Therapeutics as CSO, bringing 25 years of drug discovery expertise to advance targeted oncology therapies and precision medicine.

8 Oct 2024

AI and imaging tools to drive personalized cancer treatments in Europe

Developing new cancer treatment tools, using imaging techniques such as PET-CT and MRI, and new radiopharmaceuticals for next-generation personalized therapies ("Theranostics") to target cancer first at the "diagnosis" phase and then at the "therapy" phase, using the same biological targets ("see to treat").

8 Oct 2024