Fatty Acids News and Research

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Researchers develop mild mitochondrial uncouplers for obesity treatment

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health.

24 Dec 2025

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Plant-based omega-3s work better than expected in a year-long diet study

A year-long, diet-controlled intervention shows that flaxseed oil–derived alpha-linolenic acid significantly increases erythrocyte EPA, DPA, and DHA across omnivorous, vegetarian, and vegan diets. The magnitude of improvement is driven mainly by baseline omega-3 status, while absolute EPA and DHA levels in vegans remain lower than in omnivores.

17 Dec 2025

Lysophosphatidylcholines show gene-dependent effects in early Alzheimer’s disease

A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs-compounds that transport a variety of healthy fatty acids to the brain-either promote Alzheimer's or protect against it, depending on a person's genetics.

17 Dec 2025

High fructose intake increases fatty liver risk

Excessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.

16 Dec 2025

What Americans eat is driving global nutrition research

WWEIA data, a cornerstone of national dietary surveillance, drives nutrition research and policy, enhancing understanding of dietary trends and health outcomes.

16 Dec 2025

How ultra-processed foods shape Crohn’s disease risk and what dietary strategies can really help

This narrative review synthesizes evidence showing that higher intake of ultra-processed foods is consistently associated with increased Crohn’s disease risk, with mechanistic pathways implicating emulsifiers, carrageenan, maltodextrin, titanium dioxide, sweeteners and salt. It also highlights that minimally processed dietary strategies, including EEN and CDED, show therapeutic promise, particularly in pediatric Crohn’s disease.

11 Dec 2025

How much omega-3 do you need daily? New global review reveals DHA and EPA requirements

Global and national guidelines for long-chain omega-3 intake vary widely across life stages, with many countries lacking clear recommendations. Most authorities advise at least 250 mg/day of EPA and DHA, yet population intakes remain far below optimal levels.

10 Dec 2025

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025

Industrial and farm chemicals quietly alter the balance of gut microbes

This study systematically screened over 1,000 agricultural and industrial chemicals and found that many can inhibit human gut bacteria in vitro. Beyond antimicrobial effects, these chemicals act as selective pressures that can reshape microbial competition, tolerance mechanisms, and metabolic pathways.

8 Dec 2025

Why soybean oil may fuel weight gain

Researchers investigate how soybean oil may disrupt fat metabolism to potentially increase the risk of obesity.

4 Dec 2025

Insect flour could boost gut health and cut environmental impact

Chitin-rich insect flours show promise as functional foods, boosting beneficial gut bacteria while addressing allergenicity and consumer trust issues.

3 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

Most of the world falls short on omega-3 intake

More than three-quarters of the global population aren't getting enough Omega-3, according to new research from the University of East Anglia, the University of Southampton and Holland & Barrett.

1 Dec 2025

How the gut microbiome links obesity to colorectal cancer

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and colorectal cancer.

28 Nov 2025

Chronic drinking weakens the blood-brain barrier through the gut

Chronic alcohol consumption disrupts the blood-brain barrier, but Faecalibacterium prausnitzii shows promise in repairing this damage and improving cognition.

27 Nov 2025

Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

Diet swap alters breast milk composition within six days

Swapping beef for a plant-based meat substitute changed breast milk composition in just six days - even when the rest of the diet was made up of whole, unprocessed foods - according to a first-of-its-kind study from researchers at The University of Texas at Austin.

21 Nov 2025